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Anti-CCP Antibody

Anti-CCP Antibody near me in Cuttack

Also referred as

Cyclic citrullinated peptide antibody

Anti-citrullinated peptide antibody

Citrulline antibody

Anti-cyclic citrullinated peptide

For men & women

Earliest reports in

48 hours

Contains

1 test

Know more about this test

Available at an affordable price in Cuttack with Tata 1mg labs, an Anti-CCP Antibody test helps detect the presence of anti-cyclic citrullinated peptide (Anti-CCP) antibodies in the blood, which are associated with autoimmune diseases, particularly rheumatoid arthritis (RA) and are often present in the early stages of the disease. This test detects antibodies that target proteins containing citrulline, a modified amino acid found in inflamed tissues. It helps differentiate RA from other types of arthritis.

Your doctor may suggest an Anti-CCP Antibody test if you exhibit symptoms such as joint pain, warmth, swelling, morning stiffness, or nodules under the skin suggestive of RA. Upon progression, symptoms often extend to the wrists, knees, ankles, elbows, hips, and shoulders, varying in severity and sometimes occurring intermittently. No fasting is required for this test; you may continue your regular eating and drinking routine.

Samples required

Blood

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Why is this test booked?

Preparations

No special preparation is required.

Sample Collection

Who will collect your samples?

Understanding Anti-CCP Antibody

Rheumatoid arthritis, also known as RA, is an autoimmune (a condition in which the body's natural defense system mistakenly attacks normal/healthy cells) and an inflammatory condition that causes inflammation (painful swelling) of the joints. In addition to the joints, RA sometimes also affects other body parts, including skin, eyes, lungs, or heart.

An Anti-CCP Antibody test helps in the early detection of RA by measuring the presence and levels of antibodies called anti-CCP (anti-cyclic citrullinated peptide) in the blood. The immune system produces these antibodies in response to the citrullinated peptides present in the joints of individuals with RA. Anti-CCP antibodies are particular to RA, and their presence can be detected even before the symptoms manifest.

According to some studies, more than 75% of people with rheumatoid arthritis test positive for CCP antibodies. Hence, this test can distinguish rheumatoid arthritis from other types of arthritis or conditions with similar symptoms, such as psoriatic arthritis and juvenile idiopathic arthritis, and is more specific than other traditional tests, such as the Rheumatoid Factor-Quantitative test.

Your doctor may recommend an Anti-CCP Antibody test if you show signs and symptoms of rheumatoid arthritis, such as pain, warmth, swelling, morning stiffness in the joints, nodules under the skin, etc. A positive result indicates the presence of anti-CCP antibodies, suggesting a higher likelihood of rheumatoid arthritis. In contrast, a negative result doesn't completely rule out RA; it may indicate a lower probability, especially when combined with clinical and other laboratory findings.

Usually, no special preparation is required for this test; you can eat and drink as per your daily routine. The test results may vary depending on age, gender, health history, and other risk factors. Narrate your complete medical history to help the doctor correlate your clinical and laboratory findings. This will help them determine your medical condition, make recommendations for diet, physical activity, and medication if needed, and manage your condition by formulating your overall treatment plan.

What does Anti-CCP Antibody measure?

An Anti-CCP Antibody test measures the presence of antibodies against cyclic citrullinated peptides (CCP) in the blood. These antibodies are collectively referred to as anti-CCP antibodies. Citrullination is a process where the amino acid arginine is converted to citrulline. In autoimmune diseases, such as rheumatoid arthritis (RA), the immune system may mistakenly identify citrullinated peptides as foreign invaders and produce antibodies against them.

Anti-CCP antibodies are considered one of the early markers of rheumatoid arthritis. They contribute to the chronic inflammation and joint damage characteristic of RA. Their presence in the blood can aid in the early diagnosis of RA, establish a prognosis for disease progression, and allow timely intervention and management.

FAQs related to Anti-CCP Antibody in Cuttack

Is there any preparation required before an Anti-CCP Antibody test?

Inform the doctor about the medications you may be taking. No other specific preparations are usually required before this test.

Is there any risk associated with an Anti-CCP Antibody test?

No, there is no risk associated with an Anti-CCP Antibody test. However, since this test involves a needle prick to withdraw the blood sample, in very rare cases, a patient may experience increased bleeding, hematoma formation (blood collection under the skin), bruising or infection at the site of needle prick.

What is citrulline?

During inflammation, arginine amino acid residues can be enzymatically converted into citrulline residues in proteins, such as vimentin, by a process called citrullination. Its production occurs during the metabolism of the amino acid arginine. It will change the structure of the protein which can trigger an immune response that produces autoantibodies against proteins in the joints.

What is rheumatoid arthritis?

Rheumatoid arthritis is a systemic autoimmune disease which is chronic (from a long time). It causes inflammation, stiffness, pain and disastrous changes in joints of the body. It can occur at any age but the usual age is after 40 years. As compared to men, women are more affected. It can progress slow or fast. But, if untreated can cause disability of the joints.

What are other tests advised for rheumatoid arthritis?

Apart from anti CCP antibody test, rheumatoid factor (RF) test, joint X rays, and blood tests are advised. If a patient has positive anti CCP antibody test as well as RF test it indicates that the patient has rheumatoid arthritis. If the patient has a positive anti CCP antibody test but negative RF test it means that the patient is likely to develop rheumatoid arthritis in the future. If anti CCP antibody test is negative but RF test is positive, it can indicate that the patient should be analyzed for other inflammatory conditions as well.

Is an Anti-CCP Antibody test screening test for rheumatoid arthritis?

No, the screening test for rheumatoid arthritis is the rheumatoid factor. But, once the RF is positive, an Anti-CCP Antibody test should be done to differentiate rheumatoid arthritis from other arthritis.

Can I book an Anti-CCP Antibody test in Cuttack near me?

Yes, you can book an Anti-CCP Antibody test in Cuttack near you with Tata 1mg Labs. The test can be booked easily, is affordable, and comes with an easy-to-understand report.

Is home sample collection possible for an Anti-CCP Antibody test in Cuttack?

Yes, home sample collection is possible for an Anti-CCP Antibody test in Cuttack with Tata 1mg Labs. You can also choose a date and time that suits your schedule for sample collection.

How can I book an Anti-CCP Antibody test with Tata 1mg Labs in Cuttack?

The booking process for an Anti-CCP Antibody test with Tata 1mg Labs in Cuttack is straightforward and hassle-free. Follow these steps to schedule a test online: 1). Go to the Lab Tests section on the Tata 1mg website. 2). Add your preferred test to the shopping cart. 3). Choose a time and day that works for you as long as you also take the essential prerequisites into account. 4). A confirmation notification will be sent to you with all the details once the booking is complete.

What is the cost of an Anti-CCP Antibody test in Cuttack?

Tata 1mg Labs allows you to book tests at an affordable price in Cuttack. An Anti-CCP Antibody test can be booked at a pocket-friendly budget of Rs. 1299.

How long does it take Tata 1mg Labs to provide the reports of an Anti-CCP Antibody test in Cuttack?

We at Tata 1mg Labs recognize the value of prompt results. We strive to deliver test results with quick turnaround times so you can receive the information promptly. The reports of an Anti-CCP Antibody test in Cuttack are often provided in 48 hours.

Content created by

Dr. Swati Gupta (Anand)

MBBS, MD Lab Medicine

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Last Updated

11th Nov 2024