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Chloride

Chloride

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This test measures the amount of chloride in the blood. It is an electrolyte that helps to control the amount of fluids and maintains the pH of the body. This test is recommended in case of symptoms such as prolonged vomiting, diarrhea, fatigue, weakness, dehydration, constricted breathing. It is also advised as a part of routine investigation in case of heart, kidney, liver or hypertension patients.

High levels of chloride indicate dehydration, kidney disease, acidosis and alkalosis. While low levels of chloride may be due to heart faliure, lung faliure and addison's disease.

Abnormal chloride level does not necessarily indicate a medical condition. Sometimes it can be the consequence of excessive fluid intake or excessive fluid loss due to vomiting or diarrhea. A physician should be consulted for the accurate interpretation of the results.

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What does Chloride measure?

Chloride is an essential mineral which acts as an electrolyte along with potassium, sodium, bicarbonate, etc. It helps to maintain the normal fluid and electrolyte balance of the body. It also acts as a buffer to help maintain the pH balance of the body. It also plays essential roles in metabolism. Chloride is used by the stomach to produce hydrochloric acid (HCl) for digestion. Chloride is present in all body fluids and is found in highest concentration in the blood and extracellular fluid (fluid present outside the cells).

Most of the chloride intake is through dietary salt (sodium chloride or NaCl), and a small portion through other food items. The body absorbs the required amount and the kidneys excrete the remaining through urine. The concentration of chloride in blood is maintained within a very narrow range by the body and usually increases or decreases in direct correlation with sodium levels.



FAQs related to Chloride

Hypochloremia is a condition where the blood chloride levels are below the normal range. This may occur due to: · Kidney diseases · Congestive heart failure · Body fluid loss due to vomiting or diarrhea · Lung diseases like Chronic Obstructive Pulmonary Disease (COPD) · Diseases of adrenal gland like Addison’s disease, Cushing's syndrome, etc. · Metabolic alkalosis (high blood pH) · Drugs like diuretics, corticosteroids, or laxatives · Alcoholism
Symptoms of Hypochloremia include: · Rapid fluid loss · Dehydration · Fatigue and weakness · Breathing difficulty · Vomiting and diarrhea
Hyperchloremia is the condition where blood chloride levels rise higher than the normal range. This may occur due to: · Kidney diseases · Excess saline in blood, as during intravenous saline administration in hospital · Excess consumption of salt in diet · Severe diarrhea · Dehydration · Hyperparathyroidism (over-secretion of parathyroid gland hormones) · Acute or Chronic Kidney Disease · Bromide poisoning · Metabolic acidosis (low blood pH) · Respiratory alkalosis · Certain medications like carbonic anhydrase inhibitors, laxatives, etc.
Symptoms of Hyperchloremia include: · Fatigue · Muscular weakness · Excessive thirst · Dry mucous membranes like the mouth · Hypertension (high blood pressure)
There is no risk associated with the test. However, since this test involves a needle prick to withdraw the blood sample, in very rare cases, a patient may experience increased bleeding, hematoma formation (blood collection under the skin), bruising or infection at the site of needle prick.
Inform the doctor of any medications you may be taking as medicines like corticosteroids, diuretics, laxatives, etc. can affect blood chloride levels. No other specific preparations are usually required before the Chloride Test.
Additional tests that may be prescribed in case of abnormal Chloride test result are: · Electrolyte Panel Test · Urine Chloride Test · Urinalysis · Kidney Function Test · Blood Sugar Tests
Content created by
Written by:
Dr. Lipika Khurana
BDS, PGDHHM
Reviewed by:
Dr. Swati Gupta (Anand)
MBBS, MD Lab Medicine
Want to know moreRead our editorial policy
Last Updated16th Mar 2026

Chloride test price for other cities

Price inAhmedabadRs. 136
Price inAllahabadRs. 136
Price inAmritsarRs. 136
Price inBangaloreRs. 90
Price inBhopalRs. 130

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Chloride