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Abcixirel 10mg Injection

Written By Dr. Anuj Saini, MMST, MBBS
Reviewed By Dr. Varun Gupta, MD Pharmacology, MBBS
Last updated on 12 Nov 2024 | 01:07 AM (IST)
Abcixirel 10mg Injection belongs to a group of medicines called antiplatelet medicines or blood thinners. It prevents the clotting of blood in the heart during, before, or after an angioplasty (procedure to improve blood flow to the heart).
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General Information

Contains

Abciximab (10mg)

Marketer

Reliance Life Sciences

Storage

Store in a refrigerator (2 - 8°C). Do not freeze.
The content is shown in English
Abcixirel 10mg Injection image

Product introduction

Abcixirel 10mg Injection is administered under the supervision of a doctor. Your doctor will decide the dose and duration of the medicine for you. You should continue all your other medicines that are advised by the doctor for your long-term treatment even after this injection.

Use of this medicine may cause low blood platelets and increase your risk of bleeding. Let your doctor know immediately if you see pinpoint rash or blood in your vomits, urine, or stool. Your doctor will explain the benefits and risks associated with this medicine before it is administered.

This medicine is used with caution for some people. Thus, you must inform the doctor if you are suffering from any bleeding disorder, kidney or liver disease. Also, let your doctor know if you are pregnant or breastfeeding and about all the other medications that you are taking regularly.

Uses of Abcixirel Injection

  • Unstable angina
  • Prevention of Blood clots

Benefits of Abcixirel Injection

Prevention of Blood clots
Abcixirel 10mg Injection prevents new blood clots from forming and prevents the existing ones from getting bigger. It works by blocking a substance in the body which is involved in blood clotting. Thus it helps your blood flow smoothly throughout the body. This can help reduce damage caused by clots in your lungs (pulmonary embolism), brain (stroke), heart (heart attack), or other blood vessels (thrombosis).

It can also be used to prevent clots from forming after surgery, for example, to replace a knee or hip joint. Although it does not “dissolve” blood clots, it can prevent them from getting bigger so your body can dissolve them over time. It can also make it less likely that parts of a clot will break off and travel to other parts of the body.

Side effects of Abcixirel Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Abcixirel
  • Bleeding
  • Low blood platelets

How to use Abcixirel Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Abcixirel Injection works

Abcixirel 10mg Injection is an antiplatelet medication. It works by preventing the platelets from sticking together, thereby decreasing the formation of harmful blood clots.

All substitutes for Abcixirel 10mg Injection

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

  • It is usually given by your nurse or doctor as an infusion (drip) into a vein.
  • It increases your risk of bleeding. Be careful while shaving, cutting fingernails or toenails or using sharp objects.
  • Notify your doctor if you see blood in your vomit, urine or stool (black, tarry stools or bright red blood).

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Abcixirel 10mg Injection. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Abcixirel 10mg Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding

Breast feeding

SAFE IF PRESCRIBED
Abcixirel 10mg Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving

Driving

NOT RELEVANT
Not relevant, as Abcixirel 10mg Injection is intended for use in hospitalised patients.
Kidney

Kidney

CAUTION
Abcixirel 10mg Injection should be used with caution in patients with kidney disease. Dose adjustment of Abcixirel 10mg Injection may be needed. Please consult your doctor.
Use of Abcixirel 10mg Injection is not recommended in patients with severe kidney disease.
Liver

Liver

CAUTION
Abcixirel 10mg Injection should be used with caution in patients with liver disease. Dose adjustment of Abcixirel 10mg Injection may be needed. Please consult your doctor.
Use of Abcixirel 10mg Injection is not recommended in patients with severe liver disease.

Frequently asked questions

Yes, Abcixirel 10mg Injection increases the risk of bleeding. Always be careful while doing activities that may cause an injury or bleeding. Tell your doctor immediately if you notice any abnormal bruising or bleeding.
Abcixirel 10mg Injection can interact with several medicines. Do not take any medicine without talking to your doctor.
Abcixirel 10mg Injection reduces your risk of developing blood clots in the blood vessels of your leg, lungs, heart and brain. You may not feel any difference after taking Abcixirel 10mg Injection. However, keep taking this medicine as prescribed by your doctor because you will still be getting its full benefits.

Fact Box

Chemical Class

Amino acids, Peptides analogues

Habit Forming

No

Therapeutic Class

BLOOD RELATED

Action Class

Glycoprotein IIb/IIIa Inhibitors

References

  1. Weitz JI. Blood Coagulation and Anticoagulant, Fibrinolytic, and Antiplatelet Drugs. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 870-71
  2. Zehnder JL. Drugs Used in Disorders of Coagulation. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 599.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 3-4.
  4. Fox KA, White HD, Gersh BJ, et al. Antithrombotic Agents: Platelete Inhibitors, Acute Anticoagulants, Fibrinolytics, and Chronic Anticoagulants. In: Opie LH, Gersh BJ, editors. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. pp. 354-355.
  5. Abciximab. Leiden, The Netherlands: Centocor B.V.; 1997. [Accessed 14 Mar. 2019] (online) Available from:
  6. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Abciximab. [Updated 2019 Jun 3]. [Accessed 19 Feb. 2020] (online) Available from:
  7. Central Drugs Standard Control Organisation (CDSCO). Abciximab. [Accessed 14 Mar. 2019] (online) Available from:
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Patient concerns

I have a unstable angina diognaised in 2002 through angiography now having hypertension and sometimes palpitations

Dr. Nabajit Talukdar
Dr. Nabajit Talukdar
Interventional Cardiology
see me at medanta opd.call 9XXXXXX

My father in law is being admitted in hospital due to blood clot in brain. His right leg and arm seems to be paralysed. Doctors in the hospital not briefing us on the problem exactly. Need your second opinion. His age is 67. Having Smoking habit.

Dr. Sunil Sekhri
Dr. Sunil Sekhri
Diabetology
There are blood clots in the brain arteries
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Reliance Life Sciences
Address: Dhirubhai Ambani Life Sciences Centre, R-282, TTC Area of MIDC, Thane-Belapur Road, Rabale, Navi Mumbai 400 701

Vendor Details

Country of origin: India
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