Acotrexed 100 Injection

Written By Dr. Anuj Saini, MMST, MBBS

Reviewed By Dr. Lalit Kanodia, MBA, MD Pharmacology

Last updated on 10 Sep 2024 | 01:05 AM (IST)

Acotrexed 100 Injection is used in the treatment of non-small cell lung cancer and malignant pleural mesothelioma.

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1/2

1 Injection

Genuine

Authenticity Assured

Prescription

required

Cold stored

Stored between 2-8°C

General Information

Contains

Pemetrexed (100mg)

Marketer

Accord Pharmaceuticals

Storage

Store in a refrigerator (2 - 8°C). Do not freeze.

The content is shown in English

Product introduction

Acotrexed 100 Injection is given as an injection by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

The most common side effects of this medicine include nausea, vomiting, loss of appetite, and hair loss. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with heart, liver and blood uric acid levels.

Before taking it, tell your doctor if have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using.This medicine is not recommended during pregnancy or while breastfeeding. Use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Uses of Acotrexed Injection

Non-small cell lung cancer
Malignant pleural mesothelioma

Benefits of Acotrexed Injection

Non-small cell lung cancer
Non-small cell lung cancer is one of the major kinds of lung cancer and it affects both smokers as well as non-smokers. Acotrexed 100 Injection helps treat non-small cell lung cancer and may be given alone or in combination with other medicines. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.

Malignant pleural mesothelioma
Malignant pleural mesothelioma is a form of cancer that develops in the lungs and the inner side of the ribs. It is a very aggressive form of lung cancer. Acotrexed 100 Injection is used along with some other medicines to treat this cancer. It kills the cancer cells, and prevents the further multiplication of cancer cells. This restricts the spread of cancer to other unaffected areas. Follow your doctor’s instructions carefully and consult your doctor if you have any doubts.

Side effects of Acotrexed Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Acotrexed

Nausea
Vomiting
Sore throat
Loss of appetite
Stomatitis (Inflammation of the mouth)
Hair loss
Low blood platelets
Rash
Fatigue
Anemia (low number of red blood cells)
Diarrhea
Decreased white blood cell count (neutrophils)
Neuropathy

How to use Acotrexed Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Acotrexed Injection works

Acotrexed 100 Injection interferes with the growth of DNA and RNA of the cancer cells by substituting their building blocks. It prevents the cancer cells from growing and multiplying.

All substitutes for Acotrexed 100 Injection

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine.
Inform your doctor immediately if you notice any signs of infection such as fever, sore throat, rash or severe diarrhea.

Safety advice

Alcohol

SAFE

Consuming alcohol with Acotrexed 100 Injection does not cause any harmful side effects.

Pregnancy

CONSULT YOUR DOCTOR

Acotrexed 100 Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding

CAUTION

Acotrexed 100 Injection should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.

Driving

UNSAFE

Acotrexed 100 Injection may cause side effects which could affect your ability to drive.
Acotrexed 100 Injection may make you feel tired and this may affect your ability to drive.

Kidney

CAUTION

Acotrexed 100 Injection should be used with caution in patients with kidney disease. Dose adjustment of Acotrexed 100 Injection may be needed. Please consult your doctor.
Use of Acotrexed 100 Injection is not recommended in patients with moderate to severe kidney disease.

Liver

SAFE IF PRESCRIBED

Acotrexed 100 Injection is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Acotrexed 100 Injection may not be needed in these patients. Please consult your doctor.

Frequently asked questions

Is Acotrexed 100 Injection a vesicant?

No. Acotrexed 100 Injection is not a vesicant.

Is Acotrexed 100 Injection safe?

Acotrexed 100 Injection is safe if used at prescribed doses for the prescribed duration as advised by your doctor.

Does Acotrexed 100 Injection cause hair loss?

Yes. Acotrexed 100 Injection is a prescription chemotherapy medication and hair loss is one of the possible side effects.

Fact Box

Chemical Class

Glutamic Aacid Derivatives

Habit Forming

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Antimetabolites

References

Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 946.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 1077.
Pemetrexed disodium. Basingstoke, Hampshire: Eli Lilly and Company Limited; 2004 [revised 10 Jan. 2019]. [Accessed 28 Jan. 2019] (online) Available from:
Pemetrexed. Indianapolis, Indiana: Lilly USA; 2004 [revised Sep. 2013]. [Accessed 26 Mar. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 26 Mar. 2019] (online) Available from:

Patient concerns

What is the purpose of Chemotherepy given at the time of radiotherapy in ca lung small cell carcinoma

Dr. Vijay Sharnangat

Medical Oncology and Hematology

This is given to enhance the therapeutic effect of radiation therapy which is curative for small cell lung cancer.

Good evening, my father is suffering from lung cancer naming malignant mesothelioma. The same type of cancer my grandmother have. They both died due to this cancer disease. I want to know that is this a heridatory type of cancer? Is there is any probability in future that I will suffer from this type of cancer. Actually is their any preventive type of measures that I can follow that will help me prevent in future from suffering from cancer. Is their any tests available to keep regular updates about the trace of the cancer,

Dr. Vijay Sharnangat

Medical Oncology and Hematology

Restrain from any addiction, have regular exercise, eat healthy food.It's not hereditary, please don't get afraid.

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Accord Pharmaceuticals
Address: 9B, 1st Floor, Chanayak Complex, Opp Murlidhar Society, Odhav, Ahmedabad.

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Acotrexed 100 Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

Lab tests offered by us

Why we need a prescription?

Provide right medicines

Prescriptions are complex documents. We proof read and recheck at various steps to provide you the right medication in the correct form and dose

In accordance with the law

Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945