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Actrapid 100IU/ml Solution for Injection

Written By Dr. Betina Chandolia, MDS, BDS
Reviewed By Dr. Varun Gupta, MD Pharmacology, MBBS
Last updated on 12 Nov 2024 | 01:02 AM (IST)
Actrapid 100IU/ml Solution for Injection is a short-acting insulin used to treat type 1 and type 2 diabetes mellitus. It is used together with a healthy diet and regular exercise to control blood sugar levels after meals. This helps to prevent serious complications of diabetes like kidney damage and blindness.
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General Information

Contains

Human insulin (100IU)

Marketer

Novo Nordisk India Pvt Ltd

Storage

Store in a refrigerator (2 - 8°C). Do not freeze.
The content is shown in English
Actrapid 100IU/ml Solution for Injection image

Product introduction

Actrapid 100IU/ml Solution for Injection is normally prescribed along with a long-acting type of insulin or other diabetes medicines. Your doctor or nurse will teach you the correct way of injecting it under the skin. It should be taken 20-30 minutes before a meal. Do not stop taking it unless your doctor tells you to. It is only a part of the treatment program that should also include a healthy diet, regular exercise, and weight reduction as advised by your doctor. 

Check your blood sugar levels regularly, keep track of your results and share them with your doctor. This is very important to work out the correct dose of the medicine for you. 

The most common side effect of this medicine include low blood sugar levels (hypoglycemia), injection site reactions, cold sweats, anxiety, shakiness, hunger, rapid heartbeat, headache, and nervousness. It may be seen if you do not eat right after a dose of this fast-acting insulin. To prevent this, it is important to always inject only the correct dose of medicine, have regular meals, and monitor your blood sugar levels regularly. Drinking excessive alcohol can also lead to a fall in your blood sugar levels. Other side effects include reactions at the injection site like redness or swelling. Some people gain weight while taking insulin. 

Do not use this medicine when you have low blood sugar levels (hypoglycemia). Tell your doctor if you have ever had kidney, liver, or heart problems before starting treatment. Pregnant or breastfeeding women should also consult their doctor as the dose may need to be changed.

Uses of Actrapid Solution for Injection

Benefits of Actrapid Solution for Injection

Diabetes
Actrapid 100IU/ml Solution for Injection is a short-acting type of insulin that is usually used along with other diabetes medication for controlling blood sugar levels. It replaces the insulin that is normally produced in the body. This helps the glucose get into your muscle and fat cells so your body can use it for energy. It also decreases glucose production in the liver.

Lowering of blood sugar level helps reduce the risk of getting any of the serious complications of diabetes such as kidney damage, eye damage, nerve problems, and loss of limbs. Learn exactly how, where, and when to inject this insulin for it to be most effective. Take it regularly along with proper diet and exercise for a normal, healthy life.

Side effects of Actrapid Solution for Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Actrapid
  • Hypoglycemia (low blood glucose level)
  • Weight gain
  • Injection site reactions (pain, swelling, redness)
  • Cold sweat
  • Anxiety
  • Shakiness
  • Hunger pangs
  • Fast heart rate
  • Headache
  • Nervousness

How to use Actrapid Solution for Injection

Your doctor or nurse will guide you how to use this medicine.

How Actrapid Solution for Injection works

Actrapid 100IU/ml Solution for Injection is a short-acting insulin, which starts working within 30 minutes after injection. It works similar to the insulin produced by the body. Insulin facilitates reuptake of sugar in muscle and fat cells and also suppresses the production of sugar in the liver.

All substitutes for Actrapid 100IU/ml Solution for Injection

For information purposes only. Consult a doctor before taking any medicine.

Actrapid HM Penfill (3ml Each)

by Novo Nordisk India Pvt Ltd
₹350.9/solution for injection
10% cheaper
<h3 class=bodySemiBold>Actrapid HM Penfill (3ml Each)</h3>

Actrapid 100IU/ml Flexpen (3ml Each)

by Novo Nordisk India Pvt Ltd
₹569.8/solution for injection
46% costlier
<h3 class=bodySemiBold>Actrapid 100IU/ml Flexpen (3ml Each)</h3>

Wosulin-R DispoPen

by Wockhardt Ltd
₹318.5/solution for injection
18% cheaper
<h3 class=bodySemiBold>Wosulin-R DispoPen</h3>

Xsulin R Solution for Injection

by Eris Lifesciences Ltd
₹341/solution for injection
13% cheaper
<h3 class=bodySemiBold>Xsulin R Solution for Injection</h3>

Xsulin R 100IU Solution for Injection

by Eris Lifesciences Ltd
₹341/solution for injection
13% cheaper
<h3 class=bodySemiBold>Xsulin R 100IU Solution for Injection</h3>

Quick tips

  • Take it 20 to 30 minutes before a meal.
  • Hypoglycemia (low blood sugar level) is a common side-effect. Learn how to identify and manage its symptoms (sweating, rapid heartbeat, weakness, blurry vision, headache) and teach your family as well.
  • Injection below the skin of the abdomen results in faster absorption than other injection sites.
  • Injection sites must be rotated to prevent hard lumps from developing at one site.
  • Opened vials/cartridges are good at room temperature for up to 4 weeks, while unopened vials must be placed in the refrigerator  (2°C–8°C).

Safety advice

Alcohol

Alcohol

UNSAFE
It is unsafe to consume alcohol with Actrapid 100IU/ml Solution for Injection.
Pregnancy

Pregnancy

SAFE IF PRESCRIBED
Actrapid 100IU/ml Solution for Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Breast feeding

Breast feeding

SAFE IF PRESCRIBED
Actrapid 100IU/ml Solution for Injection is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Driving

Driving

CAUTION
Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.
Kidney

Kidney

CAUTION
Actrapid 100IU/ml Solution for Injection should be used with caution in patients with kidney disease. Dose adjustment of Actrapid 100IU/ml Solution for Injection may be needed. Please consult your doctor.
Regular monitoring of blood glucose levels is recommended for dose adjustment.
Liver

Liver

CAUTION
Actrapid 100IU/ml Solution for Injection should be used with caution in patients with liver disease. Dose adjustment of Actrapid 100IU/ml Solution for Injection may be needed. Please consult your doctor.
Regular monitoring of glucose levels is recommended for dose adjustment.
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Frequently asked questions

If you are a type 1 diabetes patient, then yes, you have to take Actrapid 100IU/ml Solution for Injection for the rest of your life because your body is unable to produce sufficient insulin. Therefore, you would need Actrapid 100IU/ml Solution for Injection as an external source of insulin. However, if you are a type 2 diabetes patient, sometimes your doctor may ask you to stop Actrapid 100IU/ml Solution for Injection if you are able to manage your diabetes with proper exercise, diet and oral medicines.
Yes, Actrapid 100IU/ml Solution for Injection can be used alone or in combination with other diabetes medicines like long-acting insulin or oral diabetes medicines, along with proper diet and exercise. Follow your doctor’s advice and treatment plan to get the maximum benefit.
Actrapid 100IU/ml Solution for Injection is injected under the skin (subcutaneously). Your doctor will show you the area of your skin where you should inject it. Try not to inject on the same spot every time. Rotate between the typical injection sites, such as abdomen, buttocks, upper legs or upper arms. Never inject Humalog into a muscle or vein. Move to a new injection site every week or two. Inject in the same area of the body, making sure to move around within that area with each injection, for one or two weeks. You can then move to another area of your body and repeat the process. Use the same area for at least a week to avoid extreme blood sugar variations.
Yes. Actrapid 100IU/ml Solution for Injection is safe to use in pregnancy if prescribed by a doctor. However, please inform your doctor if you are pregnant, planning pregnancy or breastfeeding before using Actrapid 100IU/ml Solution for Injection. You may require dose modifications and your doctor will advise you to monitor your blood sugar levels regularly. You must follow the instructions of your doctor to get maximum benefits.
Yes, insulin is safe to use in type 2 diabetes if used according to your doctor's advice. Keep monitoring your blood sugar levels regularly as advised. Your dosage may need to be adjusted as per your needs. Follow the lifestyle changes as advised by your doctor. Talk to your doctor about the side effects and ways to prevent and manage them.
The side effects of Actrapid 100IU/ml Solution for Injection are injection site reactions such as redness, itching, pain and swelling. However, these are temporary and usually resolve on their own. Rarely, it can also cause lipodystrophy, which means abnormal changes in the fat tissues due to repeated insulin injections in the same area of the skin. It includes lipohypertrophy (thickening of adipose tissue) and lipoatrophy (thinning of adipose tissue), and may affect insulin absorption. Rotate insulin injection or infusion sites within the same region to reduce the risk of lipodystrophy.
Yes, the most common side effect of Actrapid 100IU/ml Solution for Injection is hypoglycemia. It happens more often if you miss or delay your food, drink alcohol, over-exercise or take other antidiabetic medicine along with it. So, do not skip meals and be consistent in the timing and amount of your meals. Take some snacks as per your requirement if you over exercise. Regular monitoring of the blood sugar level is important. Always carry some sugary candies, glucose/glucon-D or fruit juice with you. Take all the medicines prescribed by the doctor on time and consult your doctor if you notice any fluctuations in your blood sugar levels.
Yes, sometimes, in specific situations like diabetic ketoacidosis, severe hyperglycemia etc, Actrapid 100IU/ml Solution for Injection may be given as an injection into a vein (intravenous). However, in such cases, it is only given by a doctor, under continuous monitoring of blood sugar levels in a hospital setting.
You should consult your doctor for dose adjustment if you experience weight gain or loss, increased stress, illness, changes in diet such as missed meals or if you are taking alcohol. Your dose may also change if you have recently changed your exercise regime or are taking any medicines. Also, you must be vigilant for certain side effects that you may experience while using Actrapid 100IU/ml Solution for Injection. Your doctor will tell you ways to prevent them. These side effects are usually temporary but if they are very severe, you may need dose modifications.
Actrapid 100IU/ml Solution for Injection needs to be refrigerated before its first use. Unopened cartridges and unused pre-filled pens of Humalog must be stored in a refrigerator where the temperature is between 2°C to 8°C. Do not freeze and do not use Actrapid 100IU/ml Solution for Injection if it has been frozen. When the cartridge has been inserted into the injection pen, it should not be refrigerated and should be kept at room temperature, below 86°F (30°C) and must be used within 28 days or be discarded, even if they still contain Actrapid 100IU/ml Solution for Injection.
Actrapid 100IU/ml Solution for Injection is a man-made version of human insulin, produced by the process of biotechnology called recombinant DNA technology. It is sold as a sterile, aqueous, clear, and colorless solution that contains insulin aspart along with other constituents like glycerin, phenol, metacresol, zinc, sodium chloride etc.

Fact Box

Chemical Class

Insulin analogue

Habit Forming

No

Therapeutic Class

ANTI DIABETIC

Action Class

Human insulin- short acting

References

  1. Nolte MS. Pancreatic hormones and antidiabetic drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 728-37.
  2. Human Insulin. Bagsvaerd, Denmark: Novo Nordisk A/S; 2012. [Accessed 12 Mar. 2019] (online) Available from:
  3. Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-98. [Accessed 12 Mar. 2019] (online) Available from:
  4. Actrapid [Summary of Product Characteristics]. Bagsværd, Denmark; Novo Nordisk A/S, Novo Allé; 2007. [Accessed 13 October Sept. 2021] (online) Available from:
  5. Humulin [Product monograph]. Toronto, Ontario; Eli Lilly Canada Inc.; 2011. [Accessed 13 October Sept. 2021] (online) Available from:
  6. American Diabetes Association (ADA). Insulin administration (Position statement). Diabetes Care. 2004;27(Suppl 1): S106-S109. [Accessed 13 October 2021] (online) Available from:
  7. Insulin [Package Insert]. Bengaluru, India: Biocon Biologics India Limited; 2019. [Accessed 03 Jul. 2023]. (online) Available from:
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User feedback

Once A Day
43%
Thrice A Day
40%
Twice A Day
14%
Alternate Day
3%
Type 1 diabetes
100%

Patient concerns

IDDM, 13U actrapid morning, 10U actrapid Afternoon, 13U actrapid+12U insulatard night Need diet chart

Dr. Sanjay Bhatt
Dr. Sanjay Bhatt
Physician
You need to adopt 6 times meal pattern 3 major and 3 minor means snacksA person can control his or her sugar levels by regular exercise and walk or regular aerobic exercises at least 30 to 45 minutes per day.MEDICAL NUTRITIONAL THERAPY THAT IS TO MAINTAIN CALORIES INTAKE AS PER BMI .TAKE HELP OF DIABETIC EDUCATOR. VISIT YOU DOCTOR AND LOW ALL WHAT DOCTOR SUGGESTED.IN TIME ALL ROUTINE INVESTIGATIONS SHOULD BE DONE.you souls not treat it as disease but start of a healthy life.Uncontrolled sugar levels for long time leads to lower limb weakness which is neuropathy and which is followed by foot ulcers and other complications.online prescription is not allowed without seeing pt.so contact doctor nearby for any change or dose adjustment or visit my clinic at gurgaon sector 52 RdCity snergy multi speciality clinic near SRS MARKET

Gm sir my self v.k tiwari mbbs i feel the patient information above he is my regular patient he is suffering from serious diabetes with asthma(copd) need corticosteroids is there any safe corticosteroids for diabetic patient

Dr. Pushkar Mani
Dr. Pushkar Mani
Physician
no when u give steroid, in Inpatient , admit it or home treatment, manage with RBS charting , and H actrapid sliding scale mechanism
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Novo Nordisk India Pvt Ltd
Address: Plot No.32, 47-50, EPIP Area, Whitefield, Bangalore - 560 066

Vendor Details

Country of origin: Brazil

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