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Apidra 100IU/ml Solution for Injection

Written By Dr. Anuj Saini, MMST, MBBS
Reviewed By Dr. Ashish Ranjan, MD (Pharmacology), MBBS
Last updated on 12 Nov 2024 | 01:09 AM (IST)
Apidra 100IU/ml Solution for Injection is used to improve blood sugar control in people with type 1 and type 2 diabetes mellitus. It is a fast-acting type of insulin that helps to lower blood sugar levels after meals and reduce the chances of developing serious complications of diabetes.
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General Information

Contains

Insulin Glulisine (100IU)

Marketer

Sanofi India Ltd

Storage

Store in a refrigerator (2 - 8°C). Do not freeze.
The content is shown in English
Apidra 100IU/ml Solution for Injection image
Apidra 100IU/ml Solution for Injection image
Apidra 100IU/ml Solution for Injection image

Product introduction

Apidra 100IU/ml Solution for Injection is normally prescribed along with a long-acting type of insulin or other diabetes medicines. Your doctor or nurse will teach you the correct way of injecting it under the skin. It should be taken 15 minutes before a meal or within 20 minutes after starting a meal. Do not stop taking it unless your doctor tells you to. It is only part of a treatment program that should also include a healthy diet, regular exercise, and weight reduction as advised by your doctor.

Check your blood sugar levels regularly, keep track of your results and share them with your doctor. This is very important to work out the correct dose of the medicine for you.

The most common side effects of this medicine include hypoglycemia, allergic reactions, injection site reactions, lipodystrophy, itching, rash, and upper respiratory tract infections. To prevent these, it is important to always inject the correct dose of medicine, have regular meals (do not skip), and monitor your blood sugar levels regularly.

Do not use this medicine when you have low blood sugar levels (hypoglycemia). Tell your doctor if you have ever had kidney, liver, or heart problems before starting treatment. Pregnant or breastfeeding women should consult their doctor before using it.

Uses of Apidra Solution for Injection

Benefits of Apidra Solution for Injection

Diabetes
Apidra 100IU/ml Solution for Injection is a modern, rapid-acting form of insulin that helps to control high blood glucose (sugar) levels. It replaces the insulin that is normally produced in the body. This helps the glucose get into your cells so your body can use it for energy. It begins to lower your blood glucose level within 10-20 minutes of injecting it and the effect can last for 3-5 hours. You will need to learn exactly how, where, and when to inject this medicine for it to be most effective.

Lowering blood glucose levels helps reduce the risk of getting any of the serious complications of diabetes such as kidney damage, eye damage, nerve problems, and loss of limbs. Taking this medicine regularly along with proper diet and exercise will help you live a normal, healthy life.

Side effects of Apidra Solution for Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Apidra
  • Hypoglycemia (low blood glucose level)
  • Allergic reaction
  • Injection site reactions (pain, swelling, redness)
  • Lipodystrophy (skin thickening or pits at the injection site)
  • Itching
  • Rash
  • Upper respiratory tract infection

How to use Apidra Solution for Injection

Your doctor or nurse will guide you how to use this medicine.

How Apidra Solution for Injection works

Apidra 100IU/ml Solution for Injection is fast-acting insulin which starts working within 10-20 minutes after injecting. It works similar to the insulin produced by the body. Insulin facilitates reuptake of glucose in muscle and fat cells and also blocks the release of glucose from the liver.

Quick tips

  • Apidra 100IU/ml Solution for Injection helps to control blood sugar level and avoid long-term complications.
  • You should continue to exercise regularly, eat a healthy diet and take your other diabetes medicines along with Apidra 100IU/ml Solution for Injection.
  • Take it 15 minutes before a meal or within 20 minutes after starting a meal.
  • Injection sites must be rotated to prevent hard lumps from developing at one site.
  • Injection below the skin of the abdomen results in faster absorption than other injection sites.
  • Do not use it if the preparation is no longer clear and colorless or if it contains particles.
  • Hypoglycemia (low blood sugar level) is a common side effect. Monitor your blood sugar level regularly. 
  • Always carry some sugary food or fruit juice with you in case you experience hypoglycemia symptoms such as cold sweats, cool pale skin, tremors, weakness, and anxiety.
  • Opened vials/cartridges stay good at room temperature for up to 4 weeks, while unopened vials must be placed in the refrigerator (2°C–8°C).

Safety advice

Alcohol

Alcohol

UNSAFE
It is unsafe to consume alcohol with Apidra 100IU/ml Solution for Injection.
Pregnancy

Pregnancy

SAFE IF PRESCRIBED
Apidra 100IU/ml Solution for Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Information regarding the use of Apidra 100IU/ml Solution for Injection during breastfeeding is not available. Please consult your doctor.
Driving

Driving

CAUTION
Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.
Kidney

Kidney

CAUTION
Apidra 100IU/ml Solution for Injection should be used with caution in patients with kidney disease. Dose adjustment of Apidra 100IU/ml Solution for Injection may be needed. Please consult your doctor.
Regular monitoring of blood glucose levels is recommended for dose adjustment.
Liver

Liver

CAUTION
Apidra 100IU/ml Solution for Injection should be used with caution in patients with liver disease. Dose adjustment of Apidra 100IU/ml Solution for Injection may be needed. Please consult your doctor.
Frequent and regular monitoring of blood glucose levels is advised.
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Frequently asked questions

You have to be extra careful if you are planning to take both pioglitazone and Apidra 100IU/ml Solution for Injection. Consult your doctor first before taking any other medicine. The doctor will suggest if you can safely take Apidra with pioglitazone and if you would need regular follow-up. This is because Pioglitazone can cause fluid retention in your body, especially when used in combination with insulin. You may develop symptoms of heart failure like edema, swelling of hands and feet, weight gain, breathlessness, etc. Also if you already have heart failure, it may get aggravated.
It is correct that you should not use the same spot again, as it can cause changes in the fatty tissue just under the skin. It can either cause lipodystrophy or lipohypertrophy. Lipodystrophy means abnormal changes in the distribution of body fat. It includes lipohypertrophy (thickening of adipose tissue) and lipoatrophy (thinning of adipose tissue), and may affect insulin absorption. Rotate insulin injection or infusion sites within the same region to reduce the risk of lipodystrophy.
Apidra 100IU/ml Solution for Injection contains a fast-acting insulin. Injecting Apidra into a muscle would make its absorption even more rapid. As a result, the chance of having a serious episode of hypoglycemia or low blood sugar would increase. Therefore, you should inject the insulin just beneath the skin by pinching up some skin and fat.<br>
Yes, you need to be careful because symptoms of low blood sugar (hypoglycemia) like increased heart rate may not be noticed by you. Keep a regular check on your blood sugar and consult your doctor if the problem persists.
It depends on whether you have type I diabetes mellitus (body does not produce insulin) or type II (body does not respond to insulin). For patients with type I external source of insulin is the only treatment available which cannot be stopped, as your body does not produce sufficient insulin. But for patients with type II diabetes mellitus, the doctor may stop Apidra if your blood sugar levels are well controlled with exercise, healthy diet and other diabetes pills. However, do not stop taking it on your own without consulting your doctor as it may worsen your condition.
Yes, Apidra 100IU/ml Solution for Injection can cause hypoglycemia (low blood sugar levels). Symptoms of hypoglycemia include nausea, headache, irritability, hunger, sweating, dizziness, fast heart rate and feeling anxious or shaky. It happens more often if you miss or delay your food, drink alcohol, over-exercise or take other antidiabetic medicine along with it. So, regular monitoring of the blood sugar level is important. Always carry some sugary candies, glucose, glucon-D or fruit juice with you.
Apidra 100IU/ml Solution for Injection belongs to the class of antidiabetic medications. It is a man-made version of insulin which is prescribed in diabetic adults and children of age 1 year and above. This medicine is used to help improve blood sugar levels and glycemic control.

Fact Box

Chemical Class

Insulin analogue

Habit Forming

No

Therapeutic Class

ANTI DIABETIC

Action Class

Insulin analogues- rapid acting

References

  1. Powers AC, D’Alessio D. Endocrine Pancreas and Pharmacotherapy of Diabetes Mellitus and Hypoglycemia. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1251.
  2. Nolte MS. Pancreatic hormones and antidiabetic drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 733.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 721.
  4. Insulin glulisine. Bridgewater, New Jersey: Sanofi-Aventis U.S. LLC.; 2004 [revised Aug. 2008]. [Accessed 12 Mar. 2019] (online) Available from:
  5. Apidra [Summary of Product Characteristics]. Frankfurt, Germany: Sanofi-Aventis Deutschland GmbH; 2009. [Accessed 08 Oct. 2021] (online) Available from:
  6. Insulin glulisine [Product Monograph]. Quebec, Canada: Sanofi-Aventis Canada Inc.; 2017. [Accessed 08 Oct. 2021] (online) Available from:
  7. Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-98. [Accessed 12 Mar. 2019] (online) Available from:
  8. Insulin glulisine [Summary of Product Characteristics]. Frankfurt am Main, Germany: Sanofi-Aventis Deutschland GmbH; 2017. [Accessed 05 Jul. 2023]. (online) Available from:
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User feedback

Thrice A Day
46%
Once A Day
29%
Twice A Day
12%
Alternate Day
7%
Thrice A week
1%
Twice A Week
1%
Once A Week
1%
Four Times A Day
1%
Type 1 diabetes
50%
Type 2 diabetes
50%

Patient concerns

Taking insulin (apidra)since 4 years. Before breakfast-17mg Before lunch-17mg(with1000mg cetapine and 20mg ziten) Before dinner-22mg(lantus 30 mg) Still diabetes not under control Todays fasting-164 Pp-275

Dr. Sanjay Bhatt
Dr. Sanjay Bhatt
Physician
A person can control his or her sugar levels by regular exercise and walk or regular aerobic exercises at least 30 to 45 minutes per day.MEDICAL NUTRITIONAL THERAPY THAT IS TO MAINTAIN CALORIES INTAKE AS PER BMI .TAKE HELP OF DIABETIC EDUCATOR. VISIT YOU DOCTOR AND LOW ALL WHAT DOCTOR SUGGESTED.IN TIME ALL ROUTINE INVESTIGATIONS SHOULD BE DONE.you souls not treat it as disease but start of a healthy life.Uncontrolled sugar levels for long time leads to lower limb weakness which is neuropathy and which is followed by foot ulcers and other complications.online prescription is not allowed without seeing pt.so contact doctor nearby for any change or dose adjustment or visit my clinic at gurgaon sector 52 RdCity snergy multi speciality clinic near SRS MARKET

taking linagliptin 5mg,insuline apidra 20units b/lunch,dimicrone 60mg,glycomat25omg b/lunch my ppbs is high170mg, hb1ac is 7.2 pl comment

Dr. Sanjay Bhatt
Dr. Sanjay Bhatt
Physician
Try to do regularly basis exercise and brisk walkA person can control his or her sugar levels by regular exercise and walk or regular aerobic exercises at least 30 to 45 minutes per day.MEDICAL NUTRITIONAL THERAPY THAT IS TO MAINTAIN CALORIES INTAKE AS PER BMI .TAKE HELP OF DIABETIC EDUCATOR. VISIT YOU DOCTOR AND FOLLOW ALL WHAT DOCTOR SUGGESTED. ALWAYS IN TIME ALL ROUTINE INVESTIGATIONS SHOULD BE DONE.you SHOULD not treat it as disease but start of a healthy life.Uncontrolled sugar levels for long time leads to lower limb weakness which is neuropathy and which is followed by foot ulcers and other complications.online prescription is not allowed without seeing pt.so contact doctor nearby for any change or dose adjustment or visit my clinic at gurgaon sector 52 RdCity snergy multi speciality clinic near SRS MARKET
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Sanofi India Ltd
Address: Sanofi House, CTS No.117-B, L&T Business Park, Saki Vihar Road, Powai, Mumbai 400072

Vendor Details

Country of origin: India

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