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Apixadax 5mg Tablet

Written By Dr. Anuj Saini, MMST, MBBS
Reviewed By Dr. Varun Gupta, MD Pharmacology, MBBS
Last updated on 12 Nov 2024 | 01:09 AM (IST)
Apixadax 5mg Tablet is a medicine known as an anticoagulant or blood thinner. It helps prevent and treat blood clots. It prevents and treats clot formation in the veins of your legs, lungs, brain, and heart. It is used to reduce the risk of stroke and heart attack.
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General Information

Contains

Apixaban (5mg)

Marketer

Daxia Healthcare
The content is shown in English
Apixadax 5mg Tablet image

Product introduction

Apixadax 5mg Tablet is commonly used in patients with irregular heart rhythm (atrial fibrillation) to prevent clot formation. It also reduces the risk of getting clots in people who have undergone elective knee or hip replacement surgeries. It can be taken with or without food and it is best to take them at the same time each day. You may need to take this medicine for many years, even for life in some cases.

Do not stop taking it or change the dose without guidance from your doctor. It could quickly put you more at risk of having a heart attack, stroke, or thrombosis (formation of a blood clot within a blood vessel). You can reduce your risk of having a blood clot by making changes to your lifestyle, such as not smoking, eating a healthy diet, getting regular exercise, and losing weight if you need to.

The most common side effect of Apixadax 5mg Tablet is bleeding more easily than normal, for example, having nosebleeds or bruising. If you experience any symptoms, tell your doctor immediately. Other side effects include hematoma, anemia, and nausea.

Do not take this medicine if you have severe kidney or liver problems, if you are currently bleeding, or if you are taking other medicines to reduce blood clotting. You should not breastfeed while using this medicine. Unlike other anticoagulants, a regular blood test (PT-INR) is not required while taking this medicine.

Uses of Apixadax Tablet

  • Treatment and prevention of Blood clots

Benefits of Apixadax Tablet

Treatment and prevention of Blood clots
Formation of blood clots blocks one or more veins, usually in your legs. Apixadax 5mg Tablet is used to prevent formation of blood clots near the surface of your skin. It dissolves the clots and also relieves pain and inflammation by increasing the blood flow. This improves the overall healing process. Take it as prescribed by the doctor. The condition usually improves on its own in some time. Additionally, the doctor might recommend applying heat to the painful area, elevating the affected leg, using an over-the-counter painkiller and possibly wearing compression stockings.

Side effects of Apixadax Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Apixadax
  • Hemorrhage
  • Hematoma
  • Anemia (low number of red blood cells)
  • Bruise
  • Nausea

How to use Apixadax Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Apixadax 5mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Apixadax Tablet works

Apixadax 5mg Tablet is a novel oral anticoagulant (NOAC). It works by preventing the formation of blood clots in the body.

All substitutes for Apixadax 5mg Tablet

For information purposes only. Consult a doctor before taking any medicine.

Apigat 5 Tablet

by Natco Pharma Ltd
₹27.63/tablet
50% cheaper
<h3 class=bodySemiBold>Apigat 5 Tablet</h3>

Apixapil 5 Tablet

by Alkem Laboratories Ltd
₹10.8/tablet
80% cheaper
<h3 class=bodySemiBold>Apixapil 5 Tablet</h3>

Apigy 5 Tablet

by Cipla Ltd
₹20.9/tablet
62% cheaper
<h3 class=bodySemiBold>Apigy 5 Tablet</h3>

Apixator 5 Tablet

by Torrent Pharmaceuticals Ltd
₹16.45/tablet
70% cheaper
<h3 class=bodySemiBold>Apixator 5 Tablet</h3>

Abaxis 5 Tablet

by Intas Pharmaceuticals Ltd
₹20.9/tablet
62% cheaper
<h3 class=bodySemiBold>Abaxis 5 Tablet</h3>

Quick tips

  • Apixadax 5mg Tablet can be taken with or without food. Night time administration is not preferable.
  • It interacts less with food or other medicines. Hence, frequent dose changes are not required.
  • It increases your risk of bleeding. Be careful while shaving, cutting fingernails or toenails, using sharp objects or engaging in contact sports (e.g. football, wrestling).
  • Inform your doctor if you see blood in your vomit, urine or stool (black, tarry stools or bright red blood).
  • If you are going to have a surgery or dental treatment, you may be asked to stop taking Apixadax 5mg Tablet temporarily.
  • Notify your doctor if you have any kidney problem.
  • Do not stop taking medication without talking to your doctor. 

Safety advice

Alcohol

Alcohol

CAUTION
Caution is advised when consuming alcohol with Apixadax 5mg Tablet. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Apixadax 5mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Use of Apixadax 5mg Tablet during pregnancy may increase the risk of bleeding during pregnancy and delivery.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Apixadax 5mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving

Driving

SAFE
Apixadax 5mg Tablet does not usually affect your ability to drive.
Kidney

Kidney

CAUTION
Apixadax 5mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Apixadax 5mg Tablet may be needed. Please consult your doctor.
Liver

Liver

CAUTION
Apixadax 5mg Tablet should be used with caution in patients with severe liver disease. Dose adjustment of Apixadax 5mg Tablet may be needed. Please consult your doctor.
However, Apixadax 5mg Tablet dose adjustment may not be needed in patients with the mild liver disease.
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Frequently asked questions

If you have difficulty swallowing the whole tablet, the tablet may be crushed and mixed with water, or 5% dextrose in water, or apple juice or apple puree. Remember to crush the medicine just before you take it.
If a dose is missed, the patient should take Apixadax 5mg Tablet immediately and then continue with twice daily intake as before.
Apixadax 5mg Tablet may cause bleeding in eyes, stomach, nose, etc and anemia which may cause tiredness or paleness. It may also lower your blood pressure which may make you faint or have a quickened heartbeat and nausea. Blood tests may show an increase in gamma glutamyltransferase (GGT), which may be due to liver problems.
Apixadax 5mg Tablet is used to reduce the risk of stroke and blood clots in people who have atrial fibrillation. In atrial fibrillation, the heart beats irregularly, increasing the chance of clots forming in the body and possibly causing strokes. Apixadax 5mg Tablet also helps to reduce the risk of forming a blood clot in the legs and lungs of people who have just had hip or knee replacement surgery and treat blood clots in the veins of your legs (deep vein thrombosis) or lungs (pulmonary embolism), and reduce the risk of them occurring again.
While using Apixadax 5mg Tablet you should be aware of the risks involved such as it can cause excessive bleeding being a blood thinner. Hence, do not stop taking the medication without speaking to your doctor. If you have epidural or spinal anesthesia or a spinal puncture while taking Apixadax 5mg Tablet then you may be at risk of developing a blood clot in or around your spine which can result in paralysis in some patients. Hence, inform the doctor beforehand if you have had any such procedure.
Consult your doctor who will tell you whether you have to stop it or not. It will depend on the type of procedure involved. For instance, if there is moderate to high risk of bleeding during the procedure you will have to stop taking Apixadax 5mg Tablet 48 hours before surgery.
Yes, Apixadax 5mg Tablet belongs to a class of medicines known as anticoagulant or blood thinner. It prevents your blood from clotting by preventing formation of an important component of blood clotting (factor Xa).
Apixadax 5mg Tablet, when taken more than the recommended dose, may cause unusual bleeding or bruising, red, brown, or pink urine, red or black, tarry stools and coughing up or vomiting blood or material that looks like coffee grounds. Consult your doctor immediately or seek emergency medical attention in a nearby hospital.

Fact Box

Chemical Class

Phenylpiperidines

Habit Forming

No

Therapeutic Class

BLOOD RELATED

Action Class

Oral Factor Xa Inhibitors

References

  1. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 79-80
  2. Fox KA, White HD, Gersh BJ, et al. Antithrombotic Agents: Platelete Inhibitors, Acute Anticoagulants, Fibrinolytics, and Chronic Anticoagulants. In: Opie LH, Gersh BJ, editors. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. pp. 366-67.
  3. Apixaban. Princeton, New Jersey: Bristol-Myers Squibb Company; 2012. [Accessed 24 Jan. 2019] (online) Available from:
  4. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Apixaban. [Updated 2018 Dec 3]. [Accessed 19 Feb. 2020] (online) Available from:
  5. Central Drugs Standard Control Organisation (CDSCO). Apixaban. [Accessed 14 Mar. 2019] (online) Available from:
  6. Apixaban [Prescribing Information]. Verna, Goa, Indoco Remedies Ltd.; 2021. [Accessed 09 Jun, 2023] (online) Available from:
  7. Northwestern Memorial Hospital. patient Education: Apixaban. [Accessed 09 Jun, 2023] (online) Available from:
  8. Drugs.com. Apixaban Pregnancy and Breastfeeding Warnings. [Accessed 14 Mar. 2019] (online) Available from:
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Patient concerns

My father in law is being admitted in hospital due to blood clot in brain. His right leg and arm seems to be paralysed. Doctors in the hospital not briefing us on the problem exactly. Need your second opinion. His age is 67. Having Smoking habit.

Dr. Sunil Sekhri
Dr. Sunil Sekhri
Diabetology
There are blood clots in the brain arteries

In 3 months pregnancy some blood clots have came

Dr. Dharna Gupta
Dr. Dharna Gupta
Obstetrics and Gynaecology
Get an USG done urgently
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Daxia Healthcare
Address: A,B,C-111, SAKAR COMPLEX, SANSTHA VASAHAT, RAOPURA, Vadodara-390001, Gujarat, India

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Apixadax 5mg Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's â„ž and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945
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