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Aplex 30mg Tablet

Written By Dr. Radhika Dua, MDS, BDS
Reviewed By Dr. Shilpa Garcha, MD (Pharmacology), MBBS
Last updated on 12 Nov 2024 | 01:02 AM (IST)
Aplex 30mg Tablet is used in the treatment of moderate to severe plaque psoriasis which is a type of skin condition. This medicine is used when other conventional treatments cannot be used or if the patient is not responsive or intolerant to any of these treatments.
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General Information

Contains

Apremilast (30mg)

Marketer

Ajanta Pharma Ltd

Storage

Store below 30°C
The content is shown in English
Aplex 30mg Tablet image

Product introduction

Aplex 30mg Tablet can be taken with or without food. Take it regularly and do not stop taking the medicine even if you get better until that doctor tells you it is alright to stop. You may need to monitor your weight regularly while taking the medicine as it may cause weight loss.

Using this medicine may cause few common side effects such as nausea, diarrhea, vomiting, headache, and upper respiratory tract infection. If these side effects persist or get worse, let your doctor know. Your doctor may help with ways to reduce or prevent these symptoms by prescribing you an alternative medicine or by adjusting the dose.

To make sure the medicine is safe for you, before taking this medicine, let your doctor know all the other medicines you are taking. If you are pregnant or breastfeeding, consult your doctor first before taking this medicine.

Uses of Aplex Tablet

  • Plaque psoriasis

Benefits of Aplex Tablet

Plaque psoriasis
Plaque psoriasis is the most common form of psoriasis, a condition where the skin cells in the body grow too quickly and form scales and dry patches. They can grow anywhere, but most appear on the scalp, elbows, knees, and lower back. Aplex 30mg Tablet reduces the scaly, itchy patches which may develop on the different parts of the body. It may take several months to become fully effective. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.

Side effects of Aplex Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Aplex
  • Diarrhea
  • Nausea
  • Vomiting
  • Headache
  • Upper respiratory tract infection

How to use Aplex Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Aplex 30mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Aplex Tablet works

Aplex 30mg Tablet is a phosphodiesterase 4 (PDE4) inhibitors. It works by blocking the action of certain chemical messengers that are responsible for inflammation associated with psoriatic arthritis and psoriasis, and thereby reduces the signs and symptoms of these conditions.

Quick tips

  • Aplex 30mg Tablet is a well-tolerated medicine. Mild stomach upset may occur early during the treatment.
  • Monitor your weight regularly as Aplex 30mg Tablet may cause weight loss.
  • Your doctor will gradually increase the dose from day 1 to day 6 of treatment, after which it may be kept constant.
  • Tell your doctor immediately if you experience new or worsened depression, suicidal thoughts, other mood changes or unexplained weight loss.
     

Safety advice

Alcohol

Alcohol

CAUTION
Caution is advised when consuming alcohol with Aplex 30mg Tablet. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Aplex 30mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Information regarding the use of Aplex 30mg Tablet during breastfeeding is not available. Please consult your doctor.
Driving

Driving

CONSULT YOUR DOCTOR
It is not known whether Aplex 30mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney

Kidney

CAUTION
Aplex 30mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Aplex 30mg Tablet may be needed. Please consult your doctor.
Liver

Liver

SAFE IF PRESCRIBED
Aplex 30mg Tablet is safe to use in patients with liver disease. No dose adjustment of Aplex 30mg Tablet is recommended.
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Frequently asked questions

No, Aplex 30mg Tablet is not an immunosuppressant. It belongs to a class of medicines known as phosphodiesterase 4 inhibitors (PDE4) which work by blocking the activity of PDE4. PDE4 is found in inflammatory cells and blocking it helps in reducing the molecules responsible for inflammation.
Aplex 30mg Tablet is used to treat plaque psoriasis (red, scaly, thick, itchy, painful patches on skin) and psoriatic arthritis (a condition that causes joint pain and swelling). It is a long-term treatment and may take about 16 weeks to show an improvement.
Yes, Aplex 30mg Tablet may cause depression as a side effect. The patient may also develop suicidal thoughts. It should be avoided in patients with a history of depression. In case you develop any of these symptoms, consult your doctor immediately or ask your friends or relatives to help seek medical advice.
Yes, Aplex 30mg Tablet may cause a decrease in appetite which may further cause weight loss. You should monitor your weight regularly while on treatment with Aplex 30mg Tablet. In case of significant weight loss, consult your doctor and consider stopping Aplex 30mg Tablet.
Be sure to take Aplex 30mg Tablet exactly as directed by your doctor. Your doctor will prescribe a low dose initially. This dose will be increased gradually after 6 days. Swallow the tablets whole with water. You can take it with or without food.
You should not take rifampicin if you are taking Aplex 30mg Tablet. Rifampicin interferes with the working of Aplex 30mg Tablet by decreasing its levels, making it less effective. As a result, you may not see any improvement after taking Aplex 30mg Tablet.
In case you get pregnant while taking Aplex 30mg Tablet, you should inform your doctor immediately. In fact, pregnancy should be avoided during treatment with this medicine. The reason being, according to animal studies, with Aplex 30mg Tablet there may be a risk of baby loss or defects in unborn baby.

Fact Box

Chemical Class

Isoindole Derivative

Habit Forming

No

Therapeutic Class

PAIN ANALGESICS

Action Class

Phosphodiesterase-IV inhibitors (PsA & PSO)

References

  1. Medscape. Apremilast. [Accessed 02 Apr. 2019] (online) Available from:
  2. National Drug Monograph. Apermilast; 2015. [Accessed 02 Apr. 2019] (online) Available from:
  3. Apremilast [Prescribing Information]. Thousand Oaks, CA: Amgen Inc.; 2021. [Accessed 20 Feb. 2024] (online) Available from:
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Patient concerns

I have plaque psoriasis. and suddenly I got pustular psoriasis in other areas where skin was normal. now it pains a lot at the affected area

Dr. Souvik Sardar
Dr. Souvik Sardar
Dermatology
See these are diseases wch can't be treated by online consultation U need to visit a dermatologist for a face to face consultation and examination Many things are to be considered before prescribing medicines in these cases

How to remove plaque any medicine or plaque removal suggest me

Dr. Rohan Bhatt
Dr. Rohan Bhatt
Dental Surgery
go for teeth scaling once
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Ajanta Pharma Ltd
Address: Ajanta House, Charkop, Kandivli West, Mumbai 400 067, India

Vendor Details

Country of origin: India

Lab tests offered by us

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