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Avangio Injection

Bevacizumab (400mg)
Genuine
Authenticity Assured
Prescription
required
Cold stored
Stored between 2-8°C
Avangio Injection is an anticancer medication. It is used in the treatment of cancer of colon and rectum, non-small cell lung cancer, kidney cancer, brain tumor, ovarian and cervical cancer. It helps to prevent the growth of new blood vessels that feed tumors and stops tumors from growing.

Written By Dr. Lipika Khurana, PGDHHM, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 11 Nov 2024 | 01:00 AM (IST)
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16 ml Injection
 
 
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General Information

Contains

Bevacizumab (400mg)

Marketer

PlasmaGen Biosciences Pvt Ltd

Storage

Store in a refrigerator (2 - 8°C). Do not freeze.
The content is shown in English
Avangio Injection image
Avangio Injection image

Product introduction

Avangio Injection is an effective medicine, first-line option when used together with other cancer medicines. It is given as an infusion. That means you get it through a small needle in your vein or through a port, which is a device placed under your skin. The doctor will decide your dose and duration and will check you for signs of an infusion reaction such as high blood pressure and trouble breathing. You keep taking Avangio Injection as long as your disease is controlled and your side effects are manageable. Your doctor will determine whether you should stop taking it or not. You may be advised to check blood pressure and levels of protein in urine while you are taking this medication.

The most common side effects of this medicine include nosebleeds, headache, high blood pressure, rhinitis, protein in urine, change in taste, dry skin, bleeding, lacrimation disorder, back pain, and exfoliative dermatitis. Inform your doctor that you are taking this medication before undergoing any surgical procedure, as the drug has ability to lower the ability of wound healing. Other than this, it also enhances your risk of bleeding thus if you notice any unusual bleeding or bleeding consult with your doctor immediately.

Inform your doctor if you are pregnant, planning pregnancy or breastfeeding. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using.

Side effects of Avangio Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Avangio
  • Nosebleeds
  • Headache
  • High blood pressure
  • Inflammation of the nose
  • Protein in urine
  • Taste change
  • Dry skin
  • Hemorrhage
  • Increased lacrimation
  • Back pain
  • Exfoliative dermatitis

How to use Avangio Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Avangio Injection works

Avangio Injection is a anti-angiogenic medication. It works by blocking a protein called vascular endothelial growth factor (VEGF). This stops the formation of blood vessels that bring oxygen and nutrients to cancerous cells.

Quick tips

  • Avangio Injection is an effective, first-line option when used together with other medicines for certain types of cancers such as colorectal, lung, cervical, and kidney cancers.
  • Avangio Injection is given as an infusion. Your doctor or nurse will monitor you for signs of an infusion reaction such as high blood pressure and trouble breathing.
  • It can lower your wound healing ability. Inform your doctor that you are taking this medication before undergoing any surgical procedure.
  • It can increase the risk of bleeding. Inform your doctor if you notice any unusual bleeding or bleeding that doesn't stop easily.
  • Your doctor may regularly check your blood pressure and levels of protein in your urine while you are on Avangio Injection.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Avangio Injection. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Avangio Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Avangio Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving

Driving

UNSAFE
Avangio Injection may cause side effects which could affect your ability to drive.
Sleepiness and fainting have been reported with Avangio Injection and this may impair your ability to drive.
Kidney

Kidney

SAFE IF PRESCRIBED
Avangio Injection is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Avangio Injection may not be needed in these patients. Please consult your doctor.
Liver

Liver

SAFE IF PRESCRIBED
Avangio Injection is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Avangio Injection may not be needed in these patients. Please consult your doctor.

Frequently asked questions

Avangio Injection is approved for the treatment of cancer of the colon or rectum that has spread to other parts of the body. It must be given along with chemotherapy. Other types of cancers that it helps with includes certain types of lung cancer, kidney cancer, ovarian cancer, cervical cancer, and glioblastoma (a type of brain tumor).
Avangio Injection is given as an infusion. That means you get it through a small needle in your vein or through a port, which is a device placed under your skin. Your doctor will decide your dose and duration and will monitor you for signs of an infusion reaction.
You keep taking Avangio Injection as long as your disease is controlled and your side effects are manageable. Your doctor will determine whether you should stop taking Avangio Injection. If your cancer progresses during this initial treatment, talk to your doctor if a different chemotherapy may be an option.
Chemotherapy attacks fast-growing cells, like cancer cells. In contrast, the purpose of Avangio Injection is to prevent the growth of new blood vessels that feed tumors. This causes the tumour to shrink, or to stop growing.
Chemotherapy is still needed along with taking Avangio Injection. It makes chemotherapy work better.

Fact Box

Chemical Class

Monoclonal antibody (mAb)

Habit Forming

No

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Vascular endothelial growth factor (VEGF) inhibitor

References

  1. Avastin (Bevacizumab) [Product Information]. [Accessed 07 Oct. 2024] (online) Available from:
  2. Avastin (Bevacizumab) [Prescribing Information]. South San Francisco, CA: Genentech, Inc.; 2022. [Accessed 07 Oct. 2024] (online) Available from:
  3. Chabner BA, Barnes J, Neal J, et al. Targeted Therapies: Tyrosine Kinase Inhibitors, Monoclonal Antibodies, and Cytokines. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1739-40.
  4. Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 955.
  5. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 142-43.
  6. Bevacizumab. South San Francisco, California: Genentech, Inc.; 2004 [revised Sep. 2011]. [Accessed 26 Mar. 2019] (online) Available from:
  7. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Bevacizumab. [Updated 2019 Jul 20]. [Accessed 18 Feb. 2020] (online) Available from:
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: PlasmaGen Biosciences Pvt Ltd
Address: no.160, kci chambers, 2nd floor, 5th main rd, chamrajpet, bengaluru, karnataka 560018

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Avangio Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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