Aveva Combipack Injection
Written By Dr. Anuj Saini, MMST, MBBS
Reviewed By Dr. Ashish Ranjan, MD (Pharmacology), MBBS
Last updated on 12 Nov 2024 | 01:02 AM (IST)
Aveva Combipack Injection is an estrogen blocker. It is used in the treatment of breast cancer in women who have gone through menopause. It works by adjusting the level of estrogen and slow down the growth of cancer cells.
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1/2
2 injections
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General Information
Contains
Fulvestrant (250mg/5ml)
Marketer
Zydus Cadila
Storage
Store in a refrigerator (2 - 8°C). Do not freeze.
The content is shown in English


Product introduction
Aveva Combipack Injection is given as an injection into the muscles under the supervision of a doctor. It should be taken as doctor your doctor's advice. The dose and how often you take it depends on what you are taking it for. Your doctor will decide how much you need to improve your symptoms. You should take this medicine for as long as it is prescribed for you.
The most common side effects of this medicine include injection site reaction, headache, vomiting, allergic reaction, and nausea. If these bother you, or appear serious, let your doctor know. There may be ways of reducing or preventing them.
Before taking this medicine, tell your doctor if you ever had kidney or liver disease or had bleeding disorder or had any blood clotting medicine. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Tell your doctor if you are pregnant, planning pregnancy or breastfeeding.
The most common side effects of this medicine include injection site reaction, headache, vomiting, allergic reaction, and nausea. If these bother you, or appear serious, let your doctor know. There may be ways of reducing or preventing them.
Before taking this medicine, tell your doctor if you ever had kidney or liver disease or had bleeding disorder or had any blood clotting medicine. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Tell your doctor if you are pregnant, planning pregnancy or breastfeeding.
Uses of Aveva Injection
Side effects of Aveva Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Aveva
- Nausea
- Vomiting
- Back pain
- Fatigue
- Hot flashes
- Decreased appetite
- Constipation
- Bone pain
- Joint pain
- Cough
- Injection site pain
- Headache
- Pain in extremity
- Musculoskeletal (bone, muscle or joint) pain
- Breathlessness
- Increased alanine aminotransferase
- Increased aspartate aminotransferase
- Weakness
How to use Aveva Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Aveva Injection works
Aveva Combipack Injection blocks the action of estrogen on breast cancer cells. This can lower or stop the growth of some breast cancer cells that need estrogen to grow.
All substitutes for Aveva Combipack Injection
For information purposes only. Consult a doctor before taking any medicine.
Quick tips
- Aveva Combipack Injection is used for the treatment of hormone dependent breast cancer.
- It should only be taken by women who have undergone menopause and cannot become pregnant.
- It is given as a slow injection into the muscles (intramuscular)Â of your buttock.
- Inform your doctor if you have any bleeding disorder, kidney or liver disease or if you are receiving any medicines to prevent blood clots.
- Do not take Aveva Combipack Injection if you are pregnant or breastfeeding.
- Aveva Combipack Injection is used for the treatment of hormone dependent breast cancer.
- It should only be taken by women who have undergone menopause and cannot become pregnant.
- It is given as a slow injection into the muscles (intramuscular)Â of your buttock.
- Inform your doctor if you have any bleeding disorder, kidney or liver disease or if you are receiving any medicines to prevent blood clots.
- Do not take Aveva Combipack Injection if you are pregnant or breastfeeding.
Safety advice

Alcohol
CAUTION
Caution is advised when consuming alcohol with Aveva Combipack Injection. Please consult your doctor.

Pregnancy
CONSULT YOUR DOCTOR
Aveva Combipack Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding
UNSAFE
Aveva Combipack Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving
SAFE
Aveva Combipack Injection does not usually affect your ability to drive.

Kidney
CAUTION
Aveva Combipack Injection should be used with caution in patients with severe kidney disease. Dose adjustment of Aveva Combipack Injection may be needed. Please consult your doctor.
Limited information is available on the use of Aveva Combipack Injection in these patients. No dose adjustment is recommended in patients with mild to moderate kidney disease.
Limited information is available on the use of Aveva Combipack Injection in these patients. No dose adjustment is recommended in patients with mild to moderate kidney disease.

Liver
CAUTION
Aveva Combipack Injection should be used with caution in patients with liver disease. Dose adjustment of Aveva Combipack Injection may be needed. Please consult your doctor.

Frequently asked questions
Aveva Combipack Injection contains a medicine, Fulvestrant which is used to treat breast cancer in women who have gone through menopause.
Your doctor would advise you the exact dose of this medicine. It is given as a slow (1 to 2 minutes) intramuscular (deep into the muscle) injection in your buttocks. It is administered by a medical healthcare professional only.
The common side effects associated with this medicine are headache, vomiting, urinary tract infection, diarrhea, vaginal bleeding, low platelets count and back pain. If any of these side effects bother you, consult with your doctor.
Aveva Combipack Injection is a medicine, which is used to treat breast cancer in women who have gone through menopause.
Your doctor would advise you the exact dose of this medicine. It is given as a slow (1 to 2 minutes) intramuscular (deep into the muscle) injection into your buttocks. It is administered by a medical healthcare professional only.
The common side effects associated with this medicine are headache, vomiting, urinary tract infection, diarrhea, vaginal bleeding, low platelets count and back pain. If any of these side effects bother you, consult with your doctor.
Fact Box
Chemical Class
Estrogens Derivatives
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Estrogen receptor antagonist
Related lab tests
References
- Masters SB. Hypothalmic & Pituitary Hormones. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 718.
- Moy B, Lee RJ, Smith M. Natural Products in Cancer Chemotherapy: Hormones and Related Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. pp. 1759-60.
- Drugs.com. Fulvestrant. [Accessed 03 Apr. 2019] (online) Available from:
- Fulvestrant. Luton, Bedfordshire: AstraZeneca UK Limited; 2004 [revised 6 Sep 2018]. [Accessed 03 Apr. 2019] (online) Available from:
- Fulvestrant. Cheshire, England: AstraZeneca UK Limited; 2002 [revised Jul. 2011]. [Accessed 03 Apr. 2019] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 04 Apr. 2019] (online) Available from:

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Patient concerns
If any symtom of brest cancer if have whats the cure
Dr. Sanjay Singh Rai
Medical Oncology and Hematology
First is confirmation of breast cancerChance of cure depends on stage of cancer
BREAST CANCER , PET REPORT SAYS INFECTION IN SKELETON.
Dr. Sanjay Singh Rai
Medical Oncology and Hematology
Metastatic breast cancer, send me previous treatment details
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
Marketer details
Name: Zydus Cadila
Address: Zydus Tower, Satellite Cross Roads,Ahmedabad – 380015 Gujarat, India.
Address: Zydus Tower, Satellite Cross Roads,Ahmedabad – 380015 Gujarat, India.
Vendor Details
Country of origin: India
A licensed vendor partner from your nearest location will deliver Aveva Combipack Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
A licensed vendor partner from your nearest location will deliver Aveva Combipack Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
In case of any issues, contact us
Email ID: [email protected]Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
Lab tests offered by us
- CBC (Complete Blood Count)
- FBS (Fasting Blood Sugar)
- Thyroid Profile Total (T3, T4 & TSH)
- HbA1c (Glycosylated Hemoglobin)
- Glucose - Postprandial
- Lipid Profile
- Vitamin D (25-Hydroxy)
- Urine R/M (Urine Routine & Microscopy)
- Coronavirus Covid-19 Test (RT-PCR technique)
- LFT (Liver Function Test)
- Kidney Function Test
- TSH (Thyroid Stimulating Hormone) Ultrasensitive
- ESR (Erythrocyte Sedimentation Rate)
- Uric Acid
- Vitamin B12
- C- Reactive Protein Quantitative
- Urine Culture and Sensitivity
- Serum Electrolyte
- Serum Calcium
- Creatinine
- Diabetes Screening
- KFT with Electrolytes (Kidney Function Test with Electrolytes)
- Cholesterol - Total
- Hemoglobin
- Complete Haemogram
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