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Barbinol 100mg Injection

Written By Dr. Swati Mishra, BDS
Reviewed By Dr. Khushbu Goel, DM, MD
Last updated on 15 Oct 2024 | 01:01 AM (IST)
Barbinol 100mg Injection belongs to a class of medicines called barbiturates. It is used to treat and prevent epilepsy (seizures). They also have hypnotic properties. This means, they slow down the activity of the brain and can make you feel sleepy or dizzy.
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Product introduction

Barbinol 100mg Injection is administered at a hospital or a clinical setting under the supervision of a doctor or a nurse. Get the injection regularly to maintain a consistent level of medicine in the body. Continue getting the injection, and do not stop it until the doctor says it is okay to stop.

Some common side effects of this medicine include nausea, diarrhea, hyperactivity, depression, confusion, decreased blood pressure, and fatigue. It may also cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Remember to consult your doctor if you notice severe rashes, especially accompanied by fever after taking this medicine. It should be noted that long-term use of this medicine can cause pain in joints.

Uses of Barbinol Injection

Benefits of Barbinol Injection

Epilepsy/Seizures
Barbinol 100mg Injection slows down electrical signals in the brain which cause seizures (fits). It can also help reduce symptoms such as confusion, uncontrollable jerking movements, loss of awareness, and fear or anxiety. The medicine can allow you to do some activities that you would otherwise be forbidden or scared to do (such as swimming and driving). It is given as an injection by a doctor or nurse and should not be self-administered. Follow your doctor’s instructions carefully to get the maximum benefit.

Side effects of Barbinol Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Barbinol
  • Drowsiness
  • Nausea
  • Diarrhea
  • Hyperactivity
  • Depression
  • Confusion
  • Decreased blood pressure
  • Fatigue
  • Headache
  • Dizziness
  • Constipation
  • Excitement
  • Hangover

How to use Barbinol Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Barbinol Injection works

Barbinol 100mg Injection controls seizures or fits by increasing the action of GABA, a chemical messenger which suppresses the abnormal and excessive activity of the nerve cells in the brain.

Quick tips

  • Barbinol 100mg Injection helps in treatment and prevention of seizures.
  • It may be habit-forming with long-term use.
  • Talk with your doctor if it stops working well. Do not take more than prescribed.
  • It may make you very sleepy. Don't drive or do anything that requires mental focus until you know how it affects you.
  • Inform your doctor if you notice pain in your joints or if you have a history of bone disease.
  • Get regular blood tests done to monitor the amount of medication in your body.
  • Talk to your doctor immediately if you notice skin rash accompanied with fever.
  • Do not stop taking the medication suddenly without talking to your doctor.

Safety advice

Alcohol

Alcohol

UNSAFE
It is unsafe to consume alcohol with Barbinol 100mg Injection.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Barbinol 100mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Barbinol 100mg Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Monitor the baby for sleepiness, skin rash, and feeding issues.
Driving

Driving

UNSAFE
Barbinol 100mg Injection may cause side effects which could affect your ability to drive.
Kidney

Kidney

CAUTION
Barbinol 100mg Injection should be used with caution in patients with kidney disease. Dose adjustment of Barbinol 100mg Injection may be needed. Please consult your doctor.
Use of Barbinol 100mg Injection is not recommended in patients with severe kidney disease.
Liver

Liver

CAUTION
Barbinol 100mg Injection should be used with caution in patients with liver disease. Dose adjustment of Barbinol 100mg Injection may be needed. Please consult your doctor.
Use of Barbinol 100mg Injection is not recommended in patients with severe liver disease.
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Frequently asked questions

Barbinol 100mg Injection is prescribed to control seizures or fits. Barbinol 100mg Injection belongs to barbiturate group of medicines. In exceptional circumstances, it is also used to treat seizures that sometimes accompany a high fever in children.
If you forget to take a dose, take it as soon as you remember. However, if it is time for the next dose, skip the forgotten dose and take the next dose. Do not double the dose to make up for the forgotten dose.
Yes, Barbinol 100mg Injection may cause addiction in patients with a history of alcoholism and drug abuse if they take it for a prolonged time. Therefore, Barbinol 100mg Injection should be avoided in such patients.
Long-term use of phenobarbital can lead to changes in the soft tissues of the body. Symptoms include pain in the joints or thickening in areas such as the palm or the bottom of the foot. If you notice any changes of this kind, tell the doctor.
No, you should not stop taking Barbinol 100mg Injection without consulting your doctor. Sudden withdrawal can cause sleeplessness, anxiety, tremor, dizziness, feeling sick, fits and delirium. The dose of Barbinol 100mg Injection should be reduced gradually.
Barbinol 100mg Injection causes folic acid deficiency which is responsible for certain types of anemia (megaloblastic anemia) in some patients. But if you take folic acid, then it may decrease the levels of Barbinol 100mg Injection in your body. This may lead to seizures. Therefore, folic acid should be avoided.
You should take Barbinol 100mg Injection for the duration advised by your doctor. This drug has a habit-forming effect, therefore, its long-term use is not recommended.
Yes, laboratory tests are available. If you feel excessively sleepy and experience tremor or balance issues or double vision, inform your doctor and get the levels checked.
Yes, suddenly stopping Barbinol 100mg Injection can cause withdrawal symptoms which include sleeplessness, anxiety, tremor, dizziness, nausea, fits, and delirium.

Fact Box

Chemical Class

Barbituric Acid Derivative

Habit Forming

Yes

Therapeutic Class

NEURO CNS

Action Class

Barbiturate

References

  1. McNamara JO. Pharmacotherapy of the Epilepsies. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 593-94.
  2. Porters RJ, Meldrum BS. Antiseizure Drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 407.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1101-104.
  4. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Phenobarbital. [Updated 2018 Oct 31]. [Accessed 20 Feb. 2020] (online) Available from:
  5. Phrnobarbitone. Romford, Essex: Martindale Pharma; 2008 [revised 19 Jan. 2018]. [Accessed 22 Mar. 2019] (online) Available from:
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Patient concerns

She has problem of epilepsy from last two years

Dr. Rahul Yadav
Dr. Rahul Yadav
Paediatrics
Hello, epilepsy and seizures cannot be treated online without physically examining the child and detailed history.

I m taking 1.5gm sodium valporate,1.5 levectram, 1gm clobezam then also seizure r their at period of weekly is there alternate treatment in Ayurveda as every time at multiplying the doses at every visit As MRI eeg every tests r normal

Dr. M. K. Ansari
Dr. M. K. Ansari
Neurology
not aware of any ayurvedic medications for epilepsy is not my specialization. However you seems to have difficult to control (intractable) seizures plz follow doctors advice deligently for ur own welfare
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Human Antibiotic Pharmaceuticals Pvt Ltd
Address: Simant Nagar, 2,, Kanchana Bihari Marg, Kalyanpur, Lucknow, Uttar Pradesh, India

Vendor Details

Country of origin: India
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