Benzz 45mg Injection

Reviewed By Dr. Shilpa Garcha, MD (Pharmacology), MBBS

Last updated on 24 Oct 2024 | 01:05 AM (IST)

Benzz 45mg Injection is used to treat cancer of the lymphatic system such as Non-Hodgkin's Lymphoma (NHL). It may also be used to treat other types of cancer as determined by your doctor. It can be used alone, or together with certain other medicines as part of combination chemotherapy.

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1 Injection

General Information

Contains

Bendamustine (45mg)

Marketer

Intas Pharmaceuticals Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Benzz 45mg Injection is given as an injection into vein under the supervision of a doctor and should not be self-administered. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

The most common side effects of this medicine include anemia (low number of red blood cells), decreased white blood cell count, infection, fatigue, nausea, and vomiting. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them.

Inform your doctor if you have a medical history, of bleeding disorders, heart or liver disease, radiation treatment or any infection. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is known to reduce the number of blood cells in your blood thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with kidney, liver and heart function during treatment with this medicine. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Uses of Benzz Injection

Benefits of Benzz Injection

Non-Hodgkin lymphoma (NHL)
Non-Hodgkin's lymphoma is a cancer of the white blood cells in our body, also called mantle-cell lymphoma. White blood cells are those cells that help us to fight infections. Benzz 45mg Injection helps to restrict cancer growth and also blocks the action of other chemicals that are required for cancer growth and further spread. Avoid being in crowds and wash your hands often to prevent any infections. Have plenty of fluids, unless otherwise advised by the doctor not to.

Blood cancer
Blood cancer, also called leukemia, is a cancer of the blood-forming tissues that decreases the body's ability to fight infection. Benzz 45mg Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.

Multiple myeloma
If you have multiple myeloma, your body is destroying bone faster than it is being replaced. This makes bones weak and painful and more likely to break. Benzz 45mg Injection may be prescribed along with other cancer treatments such as chemotherapy. It is an important part of your treatment and increases the survival rate of people with multiple myeloma. This medicine will kill the cancerous cells and prevent their further growth as well as spread to other parts of the body. Follow your doctor’s instructions carefully to get the most benefit. Supplements of calcium and Vitamin D3 are also effective and may be prescribed if you do not have high blood calcium levels.

Side effects of Benzz Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Benzz

Anemia (low number of red blood cells)
Decreased white blood cell count
Infection
Fatigue
Nausea
Fever
Vomiting
Low blood platelets
Mucosal inflammation

How to use Benzz Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Benzz Injection works

Benzz 45mg Injection is an anti-cancer medication. It works by damaging the genetic material (DNA and RNA) of the cancer cells. This stops their growth and multiplication.

Quick tips

Benzz 45mg Injection is given as an injection into vein under the supervision of a doctor.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Benzz 45mg Injection. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Benzz 45mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding

UNSAFE

Benzz 45mg Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving

CONSULT YOUR DOCTOR

It is not known whether Benzz 45mg Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.

Kidney

SAFE IF PRESCRIBED

Benzz 45mg Injection is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Benzz 45mg Injection may not be needed in these patients. Please consult your doctor.

Liver

CAUTION

Benzz 45mg Injection should be used with caution in patients with liver disease. Dose adjustment of Benzz 45mg Injection may be needed. Please consult your doctor.

Frequently asked questions

Is Benzz 45mg Injection safe?

Benzz 45mg Injection is safe if used at prescribed doses for the prescribed duration as advised by your doctor.

How does Benzz 45mg Injection work?

Benzz 45mg Injection works by destroying the DNA, thus killing the existing cancer cells and also preventing the growth and spread of new cancer cells.

Is Benzz 45mg Injection a vesicant?

Benzz 45mg Injection has vesicant properties and can seriously damage skin and underlying fat if leaks during administration.

Does Benzz 45mg Injection cause hair loss/constipation?

Yes, hair loss and constipation are the common side effects of Benzz 45mg Injection.

Does Benzz 45mg Injection cross blood brain barrier?

Yes, Benzz 45mg Injection crosses the blood brain barrier, and may be used to treat cancers spread to the brain.

Fact Box

Chemical Class

Mechlorethamine Derivative, Alkylating Agent, {Nitrogen Mustard Drug}

Habit Forming

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Alkylating agent

Related lab tests

Albumin/Globulin Ratio, Serum

Calcium

Complete Blood Count

Kidney Function Test

Peripheral Smear Examination

References

Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1684.
Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 942, 944.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 131-32.
Bendamustine hydrochloride monohydrate. Guildford, Surrey: Zentiva; 2015 [revised 29 Aug. 2018]. [Accessed 26 Mar. 2019] (online) Available from:
Bendamustine hydrochloride. Lake Forest, IL: Hospira, Inc.; 2008 [revised May 2016]. [Accessed 26 Mar. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:

Patient concerns

Non Hodgkin lymphoma of defuss large b cells

Dr. Vijay Sharnangat

Medical Oncology and Hematology

I am very much experienced in treating DLBCL

Symptoms of lymphoma And blood cancer

Dr. Vijay Sharnangat

Medical Oncology and Hematology

Symptoms could be like fever, weight loss, anorexia, lymphadenopathy.

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Intas Pharmaceuticals Ltd
Address: Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Benzz 45mg Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

Lab tests offered by us

Why we need a prescription?

Provide right medicines

Prescriptions are complex documents. We proof read and recheck at various steps to provide you the right medication in the correct form and dose

In accordance with the law

Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945

Benzz 45mg Injection

General Information

Contains

Marketer

Storage

Product introduction

Uses of Benzz Injection

Benefits of Benzz Injection

Side effects of Benzz Injection

How to use Benzz Injection

How Benzz Injection works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Frequently asked questions

Is Benzz 45mg Injection safe?

How does Benzz 45mg Injection work?

Is Benzz 45mg Injection a vesicant?

Does Benzz 45mg Injection cause hair loss/constipation?

Does Benzz 45mg Injection cross blood brain barrier?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Albumin/Globulin Ratio, Serum

Calcium

Complete Blood Count

Kidney Function Test

Peripheral Smear Examination

References

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Patient concerns

Non Hodgkin lymphoma of defuss large b cells

Symptoms of lymphoma And blood cancer

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

In case of any issues, contact us

Lab tests offered by us

Related/Popular tests