




Bigbro Tablet
Acebrophylline (100mg)
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Bigbro Tablet is used to treat and prevent symptoms of asthma, bronchitis, and chronic obstructive pulmonary disorder (a lung disorder in which flow of air to the lung is blocked). It helps in relaxing the muscles of the air passages, thus widening it and making it easier to breathe.
Written By Dr. Sakshi Sharma, BDS,
Reviewed By Dr. Lalit Kanodia, MBA, MD Pharmacology,
Last updated on 12 Nov 2024 | 01:00 AM (IST)
Written By Dr. Sakshi Sharma, BDS,
Reviewed By Dr. Lalit Kanodia, MBA, MD Pharmacology,
Last updated on 12 Nov 2024 | 01:00 AM (IST)
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General Information
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Product introduction
Bigbro Tablet can be taken with the food in evening. Take it at the same time every day to get the most benefit. The dose and how often you take it depends on what you are taking it for. Your doctor will decide how much you need to improve your symptoms. Take this medicine for as long as it is prescribed for you. Do not miss even a single dose, if in any case, you missed a dose, take it as soon as you remember or better to skip the missed dose and continue with regular dosing. It does not work immediately or prevent the already started breathing trouble, hence always carry your medical inhaler with you for an emergency.
The most common side effects of this medicine include abdominal discomfort, abdominal distension, vomiting, abdominal pain, diarrhea, constipation, and heart burn. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. Generally, it is advised not to consume alcohol or do not smoke while on treatment.
Before taking this medicine, let your doctor if you have kidney or liver disease or if you have heart-related problems. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Inform your doctor if you are pregnant or breastfeeding before starting the treatment.
The most common side effects of this medicine include abdominal discomfort, abdominal distension, vomiting, abdominal pain, diarrhea, constipation, and heart burn. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. Generally, it is advised not to consume alcohol or do not smoke while on treatment.
Before taking this medicine, let your doctor if you have kidney or liver disease or if you have heart-related problems. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Inform your doctor if you are pregnant or breastfeeding before starting the treatment.
Uses of Bigbro Tablet
- Treatment of Asthma
- Treatment of Bronchitis
- Treatment of Chronic obstructive pulmonary disease (COPD)
Benefits of Bigbro Tablet
Treatment of Asthma
Bigbro Tablet can help prevent the onset of an asthma attack if it is taken before exercise or exposure to some “triggers”. These may include house dust, pollen, pets and cigarette smoke. This medicine will allow you to exercise more freely without worrying about getting symptoms such as wheezing, coughing and shortness of breath. It allows you to live your life more freely without worrying so much about things that set off your symptoms.
Bigbro Tablet can help prevent the onset of an asthma attack if it is taken before exercise or exposure to some “triggers”. These may include house dust, pollen, pets and cigarette smoke. This medicine will allow you to exercise more freely without worrying about getting symptoms such as wheezing, coughing and shortness of breath. It allows you to live your life more freely without worrying so much about things that set off your symptoms.
Treatment of Bronchitis
Bronchitis leads to chest congestion and wheezing. Bigbro Tablet relieves symptoms of bronchitis by clearing congestion and relaxing airways.
Bronchitis leads to chest congestion and wheezing. Bigbro Tablet relieves symptoms of bronchitis by clearing congestion and relaxing airways.
Treatment of Chronic obstructive pulmonary disease (COPD)
Bigbro Tablet helps the airways in your lungs stay open. It relaxes the muscles of these airways. This makes it easier for air to get in and out. It will relieve symptoms such as tightness in your chest, shortness of breath, wheezing and coughing and help you carry out your daily activities more easily. This medicine is safe and effective. It usually starts to work within a few minutes and the effects can last up to several hours. Do not stop using it unless you are advised to by your doctor.
Bigbro Tablet helps the airways in your lungs stay open. It relaxes the muscles of these airways. This makes it easier for air to get in and out. It will relieve symptoms such as tightness in your chest, shortness of breath, wheezing and coughing and help you carry out your daily activities more easily. This medicine is safe and effective. It usually starts to work within a few minutes and the effects can last up to several hours. Do not stop using it unless you are advised to by your doctor.
Side effects of Bigbro Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Bigbro
- Vomiting
- Abdominal pain
- Drowsiness
- Heartburn
- Increased white blood cell count
- Loss of appetite
- Rash
- Itching
- Constipation
- Diarrhea
- Abdominal discomfort
- Abdominal distension
- Esophageal bleeding
- Red spots or bumps
- Breathing problems
- High white blood cell count
- Nasal inflammation
How to use Bigbro Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Bigbro Tablet is to be taken with food.
How Bigbro Tablet works
Bigbro Tablet is a mucolytic and bronchodilator. It works by relaxing the muscles of the airways and also thins and loosens mucus, making it easier to breathe.
All substitutes for Bigbro Tablet
For information purposes only. Consult a doctor before taking any medicine.
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Quick tips
- You have been prescribed Bigbro Tablet for prevention and treatment of asthma and chronic obstructive pulmonary disease (COPD).
- It should be taken at the same time each day, preferably in the evening after food.
- It does not work right away and should not be used to relieve sudden breathing problems. Always keep a fast-acting (rescue) inhaler with you.
- Your doctor may take regular blood test to monitor potassium level and the level of this medicine in your body.
- Notify your doctor if you have ever been diagnosed with kidney, liver or heart disease, or if you have a smoking history. Your dose may need to be adjusted.
- Do not discontinue use without consulting your doctor, even if you feel better.
Safety advice

Alcohol
UNSAFE
Bigbro Tablet may cause excessive drowsiness with alcohol.

Pregnancy
CONSULT YOUR DOCTOR
Information regarding the use of Bigbro Tablet during pregnancy is not available. Please consult your doctor.

Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Bigbro Tablet during breastfeeding is not available. Please consult your doctor.

Driving
SAFE
Bigbro Tablet does not usually affect your ability to drive.

Kidney
CAUTION
Bigbro Tablet should be used with caution in patients with kidney disease. Dose adjustment of Bigbro Tablet may be needed. Please consult your doctor.

Liver
CAUTION
Bigbro Tablet should be used with caution in patients with liver disease. Dose adjustment of Bigbro Tablet may be needed. Please consult your doctor.
Frequently asked questions
If you are taking birth control pills, dose of Bigbro Tablet need to be reduced as birth control pills may interfere with clearance of Bigbro Tablet, increasing its levels and chances of side effects.
Bigbro Tablet should be taken strictly as advised by the doctor. To avoid an upset stomach it should be taken with food.
One should take proper caution if you are taking furosemide along with Bigbro Tablet. This is because the combined use of these medicines may decrease the levels of potassium. Hence, regular monitoring of potassium levels is required.
Bigbro Tablet should be avoided in patients who are allergic to ambroxol, Bigbro Tablet, or theophylline. Along with that, patients suffering from low blood pressure, irregular heart beats or rhythm or history of heart attack, liver disease or kidney disorder should avoid taking Bigbro Tablet.
Bigbro Tablet comprises of theophylline-7 acetate and ambroxol which makes it effective in making the mucus more fluid and clearing the airways easily, thereby making breathing easier. This effect of Bigbro Tablet works as an added advantage over theophylline. Moreover, it also reduces the need for other medicine used to treat asthma, like salbutamol.
Fact Box
Chemical Class
Xanthinic Derivatives
Habit Forming
No
Therapeutic Class
RESPIRATORY
Action Class
Theophylline & its derivatives
Related lab tests
References
- Pozzi E. Acebrophylline: An airway mucoregulator and anti-inflammatory agent. Monaldi Arch Chest Dis. 2007;67(2):106-15. [Accessed 01 Apr. 2019] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 01 Apr. 2019] (online) Available from:
- DM Pharma. Acebrophylline [Product Information]. [Accessed 09 Jun, 2023] (online) Available from:
- CiplaMed. Acebrophylline [Prescribing Information]. [Accessed 09 Jun, 2023] (online) Available from:
- PubChem. Acebrophylline. [Accessed 01 Apr. 2019] (online) Available from:
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
Marketer details
Name: Intas Pharmaceuticals Ltd
Address: Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Address: Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Vendor Details
Country of origin: India
Lab tests offered by us
- CBC (Complete Blood Count)
- FBS (Fasting Blood Sugar)
- Thyroid Profile Total (T3, T4 & TSH)
- HbA1c (Glycosylated Hemoglobin)
- Glucose - Postprandial
- Lipid Profile
- Vitamin D (25-Hydroxy)
- Urine R/M (Urine Routine & Microscopy)
- Coronavirus Covid-19 Test (RT-PCR technique)
- LFT (Liver Function Test)
- Kidney Function Test
- TSH (Thyroid Stimulating Hormone) Ultrasensitive
- ESR (Erythrocyte Sedimentation Rate)
- Uric Acid
- Vitamin B12
- C- Reactive Protein Quantitative
- Urine Culture and Sensitivity
- Serum Electrolyte
- Serum Calcium
- Creatinine
- Diabetes Screening
- KFT with Electrolytes (Kidney Function Test with Electrolytes)
- Cholesterol - Total
- Hemoglobin
- Complete Haemogram
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