Blue-Lead Injection
Written By Dr. Anuj Saini, MMST, MBBS
Reviewed By Dr. Rajeev Sharma, MBA, MBBS
Last updated on 12 Nov 2024 | 01:01 AM (IST)
Blue-Lead Injection is a medicine used in the treatment of a condition called methemoglobinemia. Methemoglobinemia is a blood disorder in which an abnormal amount of methemoglobin is produced. This medicine reduces the methemoglobin to hemoglobin. This helps in the treatment of the condition.
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General Information
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Product introduction
Blue-Lead Injection is given as an injection by a doctor or a nurse. Do not self-administer this medicine at home. Get the complete dose of the injection for maximum benefits. Do not stop it suddenly without consulting the doctor. If your condition does not improve, let your doctor know. They may initiate an alternative treatment.
Some common side effects of this medicine include pain in extremities, chromaturia (abnormal coloration of urine), taste change, feeling hot, dizziness, sweating, nausea, skin discoloration, and headaches. It may also cause confusion and disturbances in vision, do not drive or do anything that requires mental focus until you know how this medicine affects you.
Before taking this medicine, let your doctor know if you have any medical conditions such as blood disorders such as anemia or a history of allergic reactions with this medicine. Let your doctor also know about all the other medicines that you are taking. Pregnant and breastfeeding women should consult their doctors before taking this medicine as it may cause harmful effects to the developing baby.
Some common side effects of this medicine include pain in extremities, chromaturia (abnormal coloration of urine), taste change, feeling hot, dizziness, sweating, nausea, skin discoloration, and headaches. It may also cause confusion and disturbances in vision, do not drive or do anything that requires mental focus until you know how this medicine affects you.
Before taking this medicine, let your doctor know if you have any medical conditions such as blood disorders such as anemia or a history of allergic reactions with this medicine. Let your doctor also know about all the other medicines that you are taking. Pregnant and breastfeeding women should consult their doctors before taking this medicine as it may cause harmful effects to the developing baby.
Uses of Blue-Lead Injection
- Methaemoglobinemia
Side effects of Blue-Lead Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Blue-Lead
- Pain in extremities
- Chromaturia (abnormal coloration of urine)
- Taste change
- Feeling hot
- Dizziness
- Sweating
- Skin discoloration
- Headache
How to use Blue-Lead Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Blue-Lead Injection works
Methylene blue acts as a reducing agent to reduce methemoglobin to hemoglobin. It is reduced to leucomethylene blue in the red blood cells of our body, by combining with a chemical nicotinamide adenine dinucleotide phosphate (NADPH), in the presence of an enzyme called NADPH reductase. Leucomethylene blue reduces methemoglobin to hemoglobin and restores the oxygen carrying capacity of hemoglobin. This helps in the treatment of Methemoglobinemia.
Quick tips
- Blue-Lead Injection is prescribed for the treatment of methemoglobinemia (blood disorders).
- Consult your doctor immediately if you notice any change in mental status or neuromuscular symptoms with or without gastrointestinal symptoms.
- It is advisable to take protective measures against exposure to light, because phototoxicity (sensitivity to light) may occur after administration of Blue-Lead Injection.
- Blue-Lead Injection is prescribed for the treatment of methemoglobinemia (blood disorders).
- Consult your doctor immediately if you notice any change in mental status or neuromuscular symptoms with or without gastrointestinal symptoms.
- It is advisable to take protective measures against exposure to light, because phototoxicity (sensitivity to light) may occur after administration of Blue-Lead Injection.
Safety advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Blue-Lead Injection. Please consult your doctor.

Pregnancy
CONSULT YOUR DOCTOR
Blue-Lead Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Blue-Lead Injection during breastfeeding is not available. Please consult your doctor.

Driving
UNSAFE
Blue-Lead Injection may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Blue-Lead Injection can cause confusion, dizziness, and possible eye disturbances. Do not drive until you know how the medicine affects you.
Blue-Lead Injection can cause confusion, dizziness, and possible eye disturbances. Do not drive until you know how the medicine affects you.

Kidney
CAUTION
Blue-Lead Injection should be used with caution in patients with kidney disease. Dose adjustment of Blue-Lead Injection may be needed. Please consult your doctor.

Liver
CAUTION
Blue-Lead Injection should be used with caution in patients with liver disease. Dose adjustment of Blue-Lead Injection may be needed. Please consult your doctor.

Fact Box
Chemical Class
Benzothiazines
Habit Forming
No
Therapeutic Class
OTHERS
Action Class
Mono-Amine Oxidase (MAO) inhibitors


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Patient concerns
Blue face when cry and stop breathing
Dr. Gopal Samdani
Paediatrics
The symptoms you are describing are somewhat concerning, and they should be checked out by your primary care doctor as soon as possible,There are many underlying causes of your symptoms. Specific treatment can not be given unless we establish exact underlying cause. Please consult Pediatrician. will take detail history and will examine your child in detail. At time may ask you relevant investigations if necessary. All information will be used to determine exact underlying cause of problem. Depending upon cause will prescribe you treatment.
What is APLA problem. Low cost injection wanted to me Enoxaparin injection Lonopin cost pls
Dr. Asmita Kaundal
Obstetrics and Gynaecology
its a thrombophilic disorder which can lead to miscarriage or fetal death. one injection vl coat around 700
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