Bosentas 62.5 Tablet

Reviewed By Dr. Ashish Ranjan, MD (Pharmacology), MBBS

Last updated on 12 Nov 2024 | 01:10 AM (IST)

Bosentas 62.5 Tablet is a prescription medicine used to treat pulmonary arterial hypertension (high pressure in the blood vessels that carry blood from the heart to the lungs). It even helps to improve your quality of life, exercising ability and delay in disease progression.

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₹870 MRP ₹897.133% off

General Information

Contains

Bosentan (62.5mg)

Marketer

Cipla Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Bosentas 62.5 Tablet should be taken with or without food. This medicine should be used regularly to get the most benefit from it. The dose and how often you take it depends on what you are taking it for. Your doctor will decide how much you need to improve your symptoms. You should take this medicine for as long as it is prescribed for you.

The most common side effects of this medicine include headache, swelling of the legs and ankles, and diarrhea. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. Some serious side effects which mean your doctor should know immediately include Anemia (low number of red blood cells) and abnormal liver function such as nausea, vomiting, dark urine, fever, and dark urine. Your doctor might check you for blood tests to check for anemia and liver function.

Before taking this medicine, let your doctor know if you have liver dysfunctioning. Inform your doctor if you are pregnant or breastfeeding. Women are suggested to use reliable contraceptive pills to avoid pregnancy and should continue even after one month of stopping the treatment. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works.

Uses of Bosentas Tablet

Pulmonary arterial hypertension (PAH)

Benefits of Bosentas Tablet

Pulmonary arterial hypertension (PAH)
Pulmonary arterial hypertension can cause shortness of breath, tiredness, dizziness, chest pain and swelling in your ankles and legs. It is caused by thickening of walls of the arteries that supply your lungs making it hard for blood to get through. Bosentas 62.5 Tablet relaxes the blood vessels and can help lower the blood pressure in the arteries of your lungs. You will be able to carry out your daily activities more easily and feel less tired or dizzy.

Side effects of Bosentas Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Bosentas

Headache
Ankle swelling
Edema (swelling)
Diarrhea
Anemia (low number of red blood cells)
Respiratory tract infection

How to use Bosentas Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Bosentas 62.5 Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Bosentas Tablet works

Bosentas 62.5 Tablet is an endothelin receptor blocker. It blocks the action of endothelin (a natural substance) that causes blood vessels to narrow (constrict). This narrowing increases the pressure in the blood vessels of the lungs. Bosentas 62.5 Tablet helps relax these blood vessels and increases the supply of blood to the lungs.

Quick tips

Your doctor has prescribed Bosentas 62.5 Tablet to treat high pressure in the blood vessels that carry blood from the heart to the lungs (the pulmonary arteries).
It helps improve your quality of life, exercising ability, and delay disease progression.
Notify your doctor if you are pregnant or planning to conceive or breastfeeding.
Your doctor may ask you to get routine blood tests done to check for anemia and to assess the functioning of your liver.
Do not drive or do anything requiring concentration until you know how Bosentas 62.5 Tablet affects you.
Females with reproductive potential should use a reliable form of birth control while using and 1 month after stopping Bosentas 62.5 Tablet as it is toxic to an unborn baby.
Inform your doctor if you notice weight gain, swelling of your arms and legs, or difficulty breathing.
Inform your doctor if you notice yellowing of skin/eye, dark urine, or stomach pain.

Safety advice

Alcohol

UNSAFE

Bosentas 62.5 Tablet may cause excessive drowsiness with alcohol.

Pregnancy

UNSAFE

Bosentas 62.5 Tablet is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.

Breast feeding

CONSULT YOUR DOCTOR

Bosentas 62.5 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

UNSAFE

Bosentas 62.5 Tablet may cause side effects which could affect your ability to drive.
As Bosentas 62.5 Tablet can induce hypotension (decrease of your blood pressure) which can make you feel dizzy and this can affect your ability to drive.

Kidney

SAFE IF PRESCRIBED

Bosentas 62.5 Tablet is safe to use in patients with kidney disease. No dose adjustment of Bosentas 62.5 Tablet is recommended.

Liver

CAUTION

Bosentas 62.5 Tablet should be used with caution in patients with liver disease. Dose adjustment of Bosentas 62.5 Tablet may be needed. Please consult your doctor.
Use of Bosentas 62.5 Tablet is not recommended in patients with moderate and severe liver disease.

Frequently asked questions

How is Bosentas 62.5 Tablet administered?

Bosentas 62.5 Tablet is given as a tablet form and can be taken with or without food. The tablets are to be taken twice daily in the morning and evening. The exact dosage and frequency of dose will be decided by the doctor on the basis of age and weight of the patient.

Are there chances of anemia with Bosentas 62.5 Tablet?

Yes, there are chances that Bosentas 62.5 Tablet may cause anemia. It can cause a dose-related decrease in hemoglobin in the blood which could lead to anemia. Regular hemoglobin check is advised while taking this medicine and consult your prescribing doctor for his advice. In some cases, blood transfusion is done to treat anemia.

Can I take Bosentas 62.5 Tablet if I have liver problems?

It has been found that in some cases Bosentas 62.5 Tablet can cause liver damage in patients who are prone to have liver disease. This medicine can also lead to increased liver enzymes. Hence, it should be used with caution in prone patients or in patients with history of liver disease. Before starting the medication inform your doctor if you have had a history of liver disease.

Is Bosentas 62.5 Tablet safe in pregnancy?

No, Bosentas 62.5 Tablet is not safe during pregnancy. There is evidence to show that it can cause major birth defects in the newborn baby and can harm the baby in womb. It is not advised to take Bosentas 62.5 Tablet if you are planning to become pregnant. You should use reliable contraception methods while you take Bosentas 62.5 Tablet. Consult your doctor before starting this medication or planning pregnancy.

Fact Box

Chemical Class

Sulfonamide and Pyrimidine Derivative

Habit Forming

Therapeutic Class

CARDIAC

Action Class

Endothelin receptor blocker

References

Barnes PJ. Pulmonary Pharmacology. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1059.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 154-56.
Bosentan. Beerse Belgium: Janssen-Cilag International NV; 2013 [revised Sep. 2018]. [Accessed 01 Apr. 2019] (online) Available from:
Bosentan. South San Francisco, California: Actelion Pharmaceuticals US, Inc.; 2001 [revised Aug. 2009]. [Accessed 23 Jan. 2019] (online) Available from:
Bosentan. South San Francisco, CA: Actelion Pharmaceuticals; 2001. [Accessed 01 Apr. 2019] (online) available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 01 Apr. 2019] (online) Available from:
Bosentan [Prescribing Information]. Titusville, NJ: Actelion Pharmaceuticals US, Inc.; 2022. [Accessed 09 Jun, 2023] (online) Available from:

User feedback

Patients taking Bosentas 62.5 Tablet

Twice A Day

63%

Once A Day

33%

Thrice A Day

Alternate Day

Four Times A Day

What are you using Bosentas Tablet for?

Pulmonary arterial hypertension (PAH)

88%

Others

12%

How much was the improvement?

Average

60%

Poor

27%

Excellent

13%

What were the side-effects while using Bosentas 62.5 Tablet?

Headache

100%

How do you take Bosentas Tablet?

With or without food

100%

Please rate Bosentas 62.5 Tablet on price

Expensive

100%

Patient concerns

sir i m suffering from PAH problem as my doctor says what is better for me to do as i m taking a medicine bosentas 62.5 and sildenafil tab. PAH 20 since 1 year what is the better way to get rid of this medicines

Dr. Nabajit Talukdar

Interventional Cardiology

Need to see you can meet me at medanta. Call 9XXXXXX

Bosentas tab and glybovin 1.25( glebenclamide) isnt same drug If not please check search machine to 1mg

Dr. Anshum Aneja Arora

Pulmonology

Yes bosentas tab is completely different . Do not confuse between the two meds . You can notify 1 mg support

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Cipla Ltd
Address: Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Provide right medicines

Prescriptions are complex documents. We proof read and recheck at various steps to provide you the right medication in the correct form and dose

In accordance with the law

Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945

Bosentas 62.5 Tablet

General Information

Contains

Marketer

Storage

Product introduction

Uses of Bosentas Tablet

Benefits of Bosentas Tablet

Side effects of Bosentas Tablet

How to use Bosentas Tablet

How Bosentas Tablet works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Frequently asked questions

How is Bosentas 62.5 Tablet administered?

Are there chances of anemia with Bosentas 62.5 Tablet?

Can I take Bosentas 62.5 Tablet if I have liver problems?

Is Bosentas 62.5 Tablet safe in pregnancy?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

References

User feedback

Patients taking Bosentas 62.5 Tablet

What are you using Bosentas Tablet for?

How much was the improvement?

What were the side-effects while using Bosentas 62.5 Tablet?

How do you take Bosentas Tablet?

Please rate Bosentas 62.5 Tablet on price

Patient concerns

sir i m suffering from PAH problem as my doctor says what is better for me to do as i m taking a medicine bosentas 62.5 and sildenafil tab. PAH 20 since 1 year what is the better way to get rid of this medicines

Bosentas tab and glybovin 1.25( glebenclamide) isnt same drug If not please check search machine to 1mg

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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