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Cladrim 10mg Injection

Cladribine (10mg)
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Cladrim 10mg Injection is used in the treatment of hairy cell leukemia, a cancer of the blood and bone marrow. It may be also used to treat other conditions, as determined by the doctor. It is used alone or in combination with some other medicines as a part of the combination therapy.

Written By Dr. Anuj Saini, MMST, MBBS,
Reviewed By Dr. Varun Gupta, MD Pharmacology, MBBS,
Last updated on 10 Nov 2024 | 01:12 AM (IST)
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General Information

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Cladrim 10mg Injection image
Cladrim 10mg Injection image

Product introduction

Cladrim 10mg Injection is given as an injection into the vein under the supervision of a doctor. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

The most common side effects of this medicine include nausea, fatigue, headache, and rash. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections or bleeding. Inform your doctor if you notice chills, unusual bleeding or bruising and black and tarry stools. Regular blood tests are required to check your blood cells along with heart, liver, and blood uric acid levels.

Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Uses of Cladrim Injection

Benefits of Cladrim Injection

Hairy cell leukemia
Hairy cell leukemia is a kind of blood cancer in which there is excessive production of specific white blood cells (that fight infections) and they resemble hairy-shape when seen under a microscope. Cladrim 10mg Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is an effective medicine but you should discuss the side effects and benefits of this medicine with your doctor. You should avoid drinking alcohol and smoking while having this treatment and drink plenty of water to stay hydrated.

Side effects of Cladrim Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Cladrim
  • Nausea
  • Fatigue
  • Headache
  • Rash
  • Fever
  • Injection site allergic reaction

How to use Cladrim Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Cladrim Injection works

Cladrim 10mg Injection interferes with the growth of DNA and RNA of the cancer cells by substituting their building blocks. It prevents the cancer cells from growing and multiplying.

Quick tips

  • Cladrim 10mg Injection helps treat hairy cell leukaemia.
  • It is given by a drip into a vein.
  • Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine.
  • Inform your doctor immediately if you notice any signs of infection such as fever, sore throat, rash or severe diarrhea.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Cladrim 10mg Injection. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Cladrim 10mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Cladrim 10mg Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving

Driving

UNSAFE
Cladrim 10mg Injection may cause side effects which could affect your ability to drive.
Kidney

Kidney

CAUTION
Cladrim 10mg Injection should be used with caution in patients with kidney disease. Dose adjustment of Cladrim 10mg Injection may be needed. Please consult your doctor.
Liver

Liver

CAUTION
Cladrim 10mg Injection should be used with caution in patients with liver disease. Dose adjustment of Cladrim 10mg Injection may be needed. Please consult your doctor.

Frequently asked questions

No, Cladrim 10mg Injection is not a vesicant (a chemical compound that causes severe skin, eye and mucosal pain and irritation).
No, Cladrim 10mg Injection does not cause hair loss.

Fact Box

Chemical Class

Purine 2'-deoxyribonucleosides Derivative

Habit Forming

No

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Antimetabolites

References

  1. Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1703-704.
  2. Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 948-49.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 286-87.
  4. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Cetuximab. [Updated 2018 Dec 3]. [Accessed 18 Feb. 2020] (online) Available from:
  5. Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Fresenius Kabi India Pvt Ltd
Address: Fresenius Kabi AG​ , Else-Kröner-Straße 1 ​ , 61352 Bad Homburg , Germany

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Cladrim 10mg Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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