Cleft 10 Tablet

Written By Dr. Betina Chandolia, MDS, BDS

Reviewed By Dr. Lalit Kanodia, MBA, MD Pharmacology

Last updated on 12 Nov 2024 | 01:10 AM (IST)

Cleft 10 Tablet is used in the treatment of rheumatoid arthritis and psoriatic arthritis. It helps in slowing down the progression of the disease and provide relief from pain, swelling, and redness.

Genuine

Authenticity Assured

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required

₹109 MRP ₹112.343% off

General Information

Contains

Leflunomide (10mg)

Marketer

Sun Pharmaceutical Industries Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Cleft 10 Tablet can be taken with or without food. You should take it regularly and at the same time each day to get the maximum benefit from it. Keep taking it as recommended by your doctor and complete the dose even if you feel better.

Using this medicine may cause some common side effects such as nausea, headache, dyspepsia, rash, diarrhea, and increased liver enzymes. Consult with your doctor if any of these side effects do not go away with time or get worse. Your doctor may help with ways to reduce or prevent these symptoms.

To make sure the medicine is safe for you, before taking this medicine, let your doctor know if you have any problems with your heart, kidneys, or liver. Also, tell your doctor of all the other medicines you are taking. Your doctor may recommend regular blood tests to check and make sure the medicine is not harming your liver or effecting your blood counts. Pregnant and breastfeeding mothers should consult with their doctors before taking the medicine.

Uses of Cleft Tablet

Rheumatoid arthritis
Psoriatic arthritis

Benefits of Cleft Tablet

Rheumatoid arthritis
Cleft 10 Tablet reduces pain, stiffness, and swelling in your joints and slows down the progression of bone and joint damage. This will help you do normal daily activities more easily and thus improve your quality of life. This medicine should be taken at the same time each day to get maximum benefits. Keep taking it even if you feel well because it is preventing future harm as well as improving your symptoms.

Psoriatic arthritis
Psoriatic arthritis is a form of arthritis that affects some people who have psoriasis, a condition where the skin cells in the body grow too quickly and form scales and dry patches. Psoriatic arthritis is a type of inflammatory arthritis. Symptoms include joint pain, stiffness and swelling, which may flare and subside. Cleft 10 Tablet helps reduce pain, stiffness and swelling in your spine and joints. It helps improve flexibility and prevents disease progression. This will help you lead a better and active life.

Side effects of Cleft Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Cleft

Nausea
Headache
Rash
Diarrhea
Increased liver enzymes
Dyspepsia
Dizziness
Loss of appetite
Hair loss
Weight loss
Bronchitis (inflammation of the airways)

How to use Cleft Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Cleft 10 Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Cleft Tablet works

Cleft 10 Tablet blocks the action of certain chemical messengers that are responsible for inflammation, swelling and redness associated with certain autoimmune diseases. It suppresses the underlying disease process, rather than simply treating the disease.

Quick tips

You have been prescribed Cleft 10 Tablet to control the symptoms and slow down the progression of rheumatoid arthritis.
It will take 6-8 weeks for Cleft 10 Tablet to work. Hence, keep taking the medicine.
Get blood tests done every 4 weeks. This is to make sure that Cleft 10 Tablet is not harming your liver or blood counts.
Avoid alcohol when taking Cleft 10 Tablet as it could harm your liver.
Do not take it during pregnancy or breastfeeding. Tell your doctor if you become pregnant while taking Cleft 10 Tablet.
Cleft 10 Tablet may increase the risk of infection. Avoid being close to people with cold, flu or other contagious illnesses.
Tell your doctor if you experience nausea or diarrhea.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Cleft 10 Tablet.

Pregnancy

UNSAFE

Cleft 10 Tablet is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.

Breast feeding

CONSULT YOUR DOCTOR

Cleft 10 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

UNSAFE

Cleft 10 Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Cleft 10 Tablet should be used with caution in patients with kidney disease. Dose adjustment of Cleft 10 Tablet may be needed. Please consult your doctor.

Liver

UNSAFE

Cleft 10 Tablet is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.

Frequently asked questions

Can Cleft 10 Tablet cause weight loss?

Yes, Cleft 10 Tablet may cause weight loss as a common side effect. However, weight loss due to this medicine is usually insignificant. The reason for this reduction in weight could be due to accompanying loss of appetite. Consult your doctor if your weight loss is significant.

When should patients notify their doctor?

The doctor should be informed if one has lung problems like cough, shortness of breath or if one observes symptoms of infection like fever, weakens, and flu-like symptoms. Along with that, if a person experiences allergic reactions like hives rashes and liver problems like yellowing of skin, loss of appetite then it should be consulted with the doctor. One should also inform the doctor if there is a decrease in blood cell count causing easy bruising and recurrent infections. In addition to that, the doctor should be informed if one becomes pregnant during the course of treatment.

Can I plan pregnancy after stopping Cleft 10 Tablet?

Cleft 10 Tablet takes fairly long time to get flushed out of your system. Hence, you should not plan pregnancy for at least 2 years after stopping Cleft 10 Tablet. This extensive time duration may be reduced to a few weeks by taking certain medicines which can help speed up the removal of Cleft 10 Tablet from your body.

How long does it take to see improvement after starting Cleft 10 Tablet?

Cleft 10 Tablet may take about 4 weeks or longer to show improvement in the condition. It may even take 4-6 months to show full benefits. Hence, the medicine should not be stopped if there is no significant improvement. For any further query consult your doctor who will analyze the condition.

Can Cleft 10 Tablet cause cancer?

Cleft 10 Tablet may increase your chances of cancer especially of lymph system, but this is very rare. The reason could be decreased strength of the immune system caused by Cleft 10 Tablet. Discuss with your doctor if you have concerns regarding it.

Fact Box

Chemical Class

Isoxazole Derivative

Habit Forming

Therapeutic Class

PAIN ANALGESICS

Action Class

Disease Modifying Anti-Rheumatoid Drugs (DMARDs)- Non biologics

Related lab tests

Rheumatoid Factor - Agglutination

Rheumatoid Factor - Turbidometry

Rheumatoid Factor IgG Antibody

References

Furst DE, Ulrich RW, Varkey-Altamirano C. Nonsteroidal Anti-Inflammatory Drugs, Disease Modifying Antirheumatic Drugs, Nonopioids Analgesics, & Drugs Used in Gout. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 631.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 781-84.
Leflunomide. Bridgewater, New Jersey: Sanofi-Aventis U.S. LLC; 1998 [Aug. 2015]. [Accessed 24 Jan. 2019] (online) Available from:
Leflunomide. Bridgewater, New Jersey: sanofi-aventis U.S; 2010. [Accessed 02 Apr. 2019] (online) Available from:
Central Drugs Standard Control Organisation. Leflunomide. [Accessed 08 Jul. 2023]. (online) Available from:
CiplaMed. Leflunomide [Prescribing Information]. [Last Revised: 13 May 2020]. [Accessed 08 Jul. 2023]. (online) Available from:
Memorial Sloan Kettering Cancer Center. Leflunomide. [last Updated: 12 Dec. 2022]. [Accessed 08 Jul. 2023]. (online) Available from:

User feedback

Patients taking Cleft 10 Tablet

Once A Day

91%

Twice A Day

Alternate Day

What are you using Cleft Tablet for?

Rheumatoid arthritis

100%

How much was the improvement?

Excellent

100%

What were the side-effects while using Cleft 10 Tablet?

Reduced blood cell count

100%

How do you take Cleft Tablet?

With food

100%

Please rate Cleft 10 Tablet on price

Average

100%

Patient concerns

I have joint pain in my rt wrist since 6 yrs. What are the possible reasons?

Dr. Trilok Kumar Jha

Orthopaedics

It may be Tenosynovitis, or Rheumatoid arthritis or any other type of arthritis

Sir/Ma'am, I feel pain in the heel of both the legs especially when I get up from the bed in the morning. After walking couple of steps, it goes away. there is no bone problem reported in the Xray report. Please guide me what could be the reason?

Dr. Mehtab Baig

Orthopaedic Physiotherapy

This is the test for rheumatoid arthritis

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Sun Pharmaceutical Industries Ltd
Address: Plot no 107/108,Namli block , Ranipool, East Sikkim 737135

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Provide right medicines

Prescriptions are complex documents. We proof read and recheck at various steps to provide you the right medication in the correct form and dose

In accordance with the law

Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945

Cleft 10 Tablet

General Information

Contains

Marketer

Storage

Product introduction

Uses of Cleft Tablet

Benefits of Cleft Tablet

Side effects of Cleft Tablet

How to use Cleft Tablet

How Cleft Tablet works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Frequently asked questions

Can Cleft 10 Tablet cause weight loss?

When should patients notify their doctor?

Can I plan pregnancy after stopping Cleft 10 Tablet?

How long does it take to see improvement after starting Cleft 10 Tablet?

Can Cleft 10 Tablet cause cancer?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Rheumatoid Factor - Agglutination

Rheumatoid Factor - Turbidometry

Rheumatoid Factor IgG Antibody

References

User feedback

Patients taking Cleft 10 Tablet

What are you using Cleft Tablet for?

How much was the improvement?

What were the side-effects while using Cleft 10 Tablet?

How do you take Cleft Tablet?

Please rate Cleft 10 Tablet on price

Patient concerns

I have joint pain in my rt wrist since 6 yrs. What are the possible reasons?

Sir/Ma'am, I feel pain in the heel of both the legs especially when I get up from the bed in the morning. After walking couple of steps, it goes away. there is no bone problem reported in the Xray report. Please guide me what could be the reason?

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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