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Clofozine 50mg Capsule

Written By Dr. Sakshi Sharma, BDS
Reviewed By Dr. Lalit Kanodia, MBA, MD Pharmacology
Last updated on 09 Nov 2024 | 01:08 AM (IST)
Clofozine 50mg Capsule belongs to a class of drugs known as antileprotic medicines. It is used in combination with other medicines for the treatment of leprosy. It works by stopping the growth of disease-causing organisms in the body.
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General Information

Contains

Clofazimine (50mg)

Marketer

AstraZeneca

Storage

Store below 30°C
The content is shown in English
Clofozine 50mg Capsule image

Product introduction

Clofozine 50mg Capsule should be used in the dose and duration as advised by your doctor. It should be taken with food, preferably at a fixed time. Avoid skipping any doses and finish the full course of treatment even if you feel better. Do not take a double dose to make up for a missed dose. Simply take the next dose as planned.

Some people may experience nausea, stomach upset, and vomiting as the side effects of this medicine. It may also discolor your skin, urine, saliva, tears, and other body fluids. This is normally temporary and resolves once the treatment is completed. Please consult your doctor if these side effects bother you or persist for a longer duration.

Uses of Clofozine Capsule

  • Leprosy

Benefits of Clofozine Capsule

Leprosy
Clofozine 50mg Capsule is an antibiotic medicine that is used in combination with few other medicines to treat leprosy, an infectious disease that mainly affects the skin, eyes, nose and peripheral nerves. It may take time to reach the effective dose as the medication is started at a low dose and increased slowly over time to avoid side effects. However, once the effective dose is reached, it starts showing improvement in your condition within a few days. Follow your doctor’s instructions carefully and avoid missing any dose to get maximum benefit.

Side effects of Clofozine Capsule

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Clofozine
  • Vomiting
  • Nausea
  • Diarrhea
  • Loss of appetite
  • Rash
  • Itching
  • Skin peeling
  • Skin discoloration
  • Eye discoloration
  • Abdominal pain

How to use Clofozine Capsule

Take this medicine in the dose and duration as advised by your doctor. Clofozine 50mg Capsule is to be taken with food.

How Clofozine Capsule works

Clofozine 50mg Capsule stops the growth of bacteria in the body.

All substitutes for Clofozine 50mg Capsule

For information purposes only. Consult a doctor before taking any medicine.

Fazim 50mg Capsule

by Lark Laboratories Ltd
₹1.39/capsule
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Feza 50 Capsule

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₹1.36/capsule
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Clofaz 50mg Capsule

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₹2.23/capsule
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Clofros 50 Capsule

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₹1.21/capsule
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Lepromine 50mg Capsule

by P & B Pharmaceuticals Ltd
₹1.4/capsule
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Quick tips

  • Clofozine 50mg Capsule is used in combination with other medicines for the treatment of leprosy.
  • Finish the prescribed course, even if you start to feel better. Stopping it early may make the infection come back and harder to treat.
  • Take it with or just after meal.
  • Take it as per the dose and duration prescribed by your doctor.
  • It may discolour your skin, urine, saliva, tears and other body fluids. This is normal and not harmful.

Safety advice

Alcohol

Alcohol

CAUTION
Caution is advised when consuming alcohol with Clofozine 50mg Capsule. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Clofozine 50mg Capsule may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Clofozine 50mg Capsule is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving

Driving

UNSAFE
Clofozine 50mg Capsule may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney

Kidney

CAUTION
Clofozine 50mg Capsule should be used with caution in patients with severe kidney disease. Dose adjustment of Clofozine 50mg Capsule may be needed. Please consult your doctor.
Liver

Liver

CAUTION
Clofozine 50mg Capsule should be used with caution in patients with liver disease. Dose adjustment of Clofozine 50mg Capsule may be needed. Please consult your doctor.
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Frequently asked questions

Yes, Clofozine 50mg Capsule may cause orange-pink to brownish-black discoloration of the skin within a few weeks after you start using it. This skin discoloration may take several months or years to resolve even after completion of your treatment with Clofozine 50mg Capsule. Such conditions may cause the patient to become depressed or the patient may develop suicidal thoughts. You must discuss with your doctor if you feel depressed or have any suicidal thoughts, during or after your treatment. This medicine may also cause your sweat, tears, saliva, urine, stools, and the whites of your eyes to turn red or brownish-black in color. Consult your doctor if you experience any such changes or if you have any other concerns regarding this.
Use of Clofozine 50mg Capsule should be avoided in patients who are allergic to Clofozine 50mg Capsule or any of its components. However, if you are not aware of any allergy or if you are using Clofozine 50mg Capsule for the first time, consult your doctor.
Clofozine 50mg Capsule is safe if used in the dose and duration advised by your doctor. Take it exactly as directed and do not skip any dose. Follow your doctor's instructions carefully and let your doctor know if any of the side effects bother you.
If you forget a dose of Clofozine 50mg Capsule, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take the next scheduled dose in the prescribed time. Do not double the dose to make up for the missed one as this may increase the chances of developing side effects.
No, do not stop taking Clofozine 50mg Capsule without consulting your doctor even if you feel better. Your symptoms may improve before the infection is completely cured. If you stop using Clofozine 50mg Capsule too early, the symptoms may return or worsen. Therefore, it is advised to continue taking Clofozine 50mg Capsule in the dose and duration advised by the doctor.

Fact Box

Chemical Class

Phenazines derivatives

Habit Forming

No

Therapeutic Class

ANTI INFECTIVES

Action Class

Anti leprotic

References

  1. Gumbo T. Chemotherapy of Tuberculosis, Mycobacterium Avium Complex Disease, and Leprosy. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1560.
  2. Chambers HF, Deck DH. Antimycobacterial Drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 831.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 295-96.
  4. ScienceDirect. Clofazimine. [Accessed 01 Apr. 2019] (online) Available from:
  5. Clofazimine. East Hanover, New Jersey: Novartis Pharmaceuticals; 1998 [revised Jul. 2002]. [Accessed 01 Apr. 2019] (online) Available from:
  6. Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-98. [Accessed 01 Apr. 2019] (online) Available from:
  7. Clofazimine [Prescribing Information]. East Hanover, NJ: Novartis Pharmaceuticals Corporation; 2019. [Accessed 25 Jul. 2024] (online) Available from:
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Patient concerns

white spot on body leprosy give a cream treatment for leprosy white spot and what are the precaution in this diseas

Dr. Atula Gupta
Dr. Atula Gupta
Dermatology
If leprosy then complete course of MBMDT is needed . No other precautions

Leprosy can I feed my 12 month baby

Dr. Atula Gupta
Dr. Atula Gupta
Dermatology
What treatment are you on
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: AstraZeneca
Address: Corporate & Registered Office, Block N1, 12th Floor, Manyata Embassy Business Park, Rachenahalli, Outer Ring Road, 560045, Bangalore

Vendor Details

Country of origin: India

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