Clonofast 0.25mg Tablet
Written By Dr. Swati Mishra, BDS
Reviewed By Dr. Khushbu Goel, DM, MD
Last updated on 09 Nov 2024 | 01:07 AM (IST)
Clonofast 0.25mg Tablet is a prescription medicine used to treat epilepsy (seizures) and anxiety disorder. It helps to decrease the abnormal and excessive activity of the nerve cells and calms the brain.
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General Information
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Product introduction
Clonofast 0.25mg Tablet may be taken with or without food. However, take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration as advised by your doctor as it has a high potential of habit-forming. If you have missed a dose, take it as soon as you remember it and finish the full course of treatment even if you feel better. You should not stop this medicine suddenly without talking to your doctor as it may increase the seizure frequency and can cause nausea, anxiety, flu-like symptoms, and muscle pain.
Some common side effects of this medicine include fatigue, depression and impaired coordination. It may also cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. It is important to inform your doctor if you develop any unusual changes in mood or depression as this medicine may cause suicidal thoughts.
Some common side effects of this medicine include fatigue, depression and impaired coordination. It may also cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. It is important to inform your doctor if you develop any unusual changes in mood or depression as this medicine may cause suicidal thoughts.
Uses of Clonofast Tablet
Benefits of Clonofast Tablet
Treatment of Anxiety disorder
Clonofast 0.25mg Tablet stops your brain from releasing the chemicals that make you feel anxious so it can reduce the symptoms of excessive anxiety and worry. It can also reduce feelings of restlessness, tiredness, difficulty concentrating, feeling irritable and sleep problems that often come with Anxiety Disorder. It will therefore help you go about your daily activities more easily and be more productive. Keep taking this medicine even if you feel well. Stopping suddenly can cause serious problems.
Clonofast 0.25mg Tablet stops your brain from releasing the chemicals that make you feel anxious so it can reduce the symptoms of excessive anxiety and worry. It can also reduce feelings of restlessness, tiredness, difficulty concentrating, feeling irritable and sleep problems that often come with Anxiety Disorder. It will therefore help you go about your daily activities more easily and be more productive. Keep taking this medicine even if you feel well. Stopping suddenly can cause serious problems.
Treatment of Epilepsy/Seizures
Clonofast 0.25mg Tablet slows down electrical signals in the brain which cause seizures (fits). It can also help reduce symptoms such as confusion, uncontrollable jerking movements, loss of awareness, and fear or anxiety. The medicine can allow you to do some activities that you would otherwise be forbidden or scared to do (such as swimming and driving). It can take a few weeks for this medicine to work (because the dose has to be increased slowly) and during this time you may still have seizures. Do not stop using this medicine even if you feel well, until your doctor advises you to. Missing doses may trigger a seizure.
Clonofast 0.25mg Tablet slows down electrical signals in the brain which cause seizures (fits). It can also help reduce symptoms such as confusion, uncontrollable jerking movements, loss of awareness, and fear or anxiety. The medicine can allow you to do some activities that you would otherwise be forbidden or scared to do (such as swimming and driving). It can take a few weeks for this medicine to work (because the dose has to be increased slowly) and during this time you may still have seizures. Do not stop using this medicine even if you feel well, until your doctor advises you to. Missing doses may trigger a seizure.
Side effects of Clonofast Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Clonofast
- Constipation
- Blurred vision
- Abnormal behavior
- Sleepiness
- Cognitive impairment
- Abnormality of voluntary movements
- Depression
- Nervousness
- Upper respiratory tract infection
- Allergic reaction
- Influenza
- Pain during periods
- Difficulty in speaking
- Emotional lability
- Decreased libido
- Memory impairment
- Dizziness
- Fatigue
- Drowsiness
How to use Clonofast Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Clonofast 0.25mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
How Clonofast Tablet works
Clonofast 0.25mg Tablet is a benzodiazepine. It works by increasing the action of a chemical messenger (GABA) which suppresses the abnormal and excessive activity of the nerve cells in the brain.
Quick tips
- The addiction / habit-forming potential of this medicine is very high. Take it only as per the dose and duration advised by your doctor
- It may cause dizziness. Do not drive or do anything that requires mental focus until you know how this medicine affects you.
- Avoid consuming alcohol as it may increase dizziness and drowsiness.
- Inform your doctor if you are pregnant, planning to conceive or breastfeeding.
- Inform your doctor if you experience worsen anxiety, depression angry, or violent behavior and mania while taking this medicine.
- Do not stop taking medication suddenly without talking to your doctor as that may lead to nausea, anxiety, agitation, flu-like symptoms, sweating, tremor, and confusion.
- The addiction / habit-forming potential of this medicine is very high. Take it only as per the dose and duration advised by your doctor
- It may cause dizziness. Do not drive or do anything that requires mental focus until you know how this medicine affects you.
- Avoid consuming alcohol as it may increase dizziness and drowsiness.
- Inform your doctor if you are pregnant, planning to conceive or breastfeeding.
- Inform your doctor if you experience worsen anxiety, depression angry, or violent behavior and mania while taking this medicine.
- Do not stop taking medication suddenly without talking to your doctor as that may lead to nausea, anxiety, agitation, flu-like symptoms, sweating, tremor, and confusion.
Safety advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Clonofast 0.25mg Tablet.

Pregnancy
CONSULT YOUR DOCTOR
Clonofast 0.25mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding
SAFE IF PRESCRIBED
Clonofast 0.25mg Tablet is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.

Driving
UNSAFE
Clonofast 0.25mg Tablet may cause side effects which could affect your ability to drive.

Kidney
CAUTION
Clonofast 0.25mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Clonofast 0.25mg Tablet may be needed. Please consult your doctor.
Use of Clonofast 0.25mg Tablet can cause excessive sleepiness in patients with end stage kidney disease.
Use of Clonofast 0.25mg Tablet can cause excessive sleepiness in patients with end stage kidney disease.

Liver
CAUTION
Clonofast 0.25mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Clonofast 0.25mg Tablet may be needed. Please consult your doctor.
Frequently asked questions
Clonofast 0.25mg Tablet belongs to a class of medicines called benzodiazepines and is used to treat anxiety, stop seizures (fits) or relax tense muscles. This can also help relieve difficulty sleeping (insomnia), and is usually prescribed for a short period of time, if used to treat sleeping problems. You should take it in the dose and duration advised by the doctor.
Yes, Clonofast 0.25mg Tablet causes drowsiness very commonly. It also causes forgetfulness and affects muscular function which may adversely affect your ability to drive. Sometimes, drowsiness persists even on the following day. So, in case Clonofast 0.25mg Tablet makes you sleepy and affects your alertness, you should avoid driving.
The duration of treatment with Clonofast 0.25mg Tablet is mainly as short as possible. Your doctor will evaluate you after 4 weeks of treatment in order to assess the need for continuation of treatment, especially if you do not have any symptoms. Before taking you off this medicine, your doctor may gradually decrease your dose to prevent any withdrawal side effects. Follow your doctor’s instructions carefully to get the most benefit.
No, it is not at all recommended to take alcohol with Clonofast 0.25mg Tablet since it can cause breathing problems, sleepiness and heart problems. Taking Clonofast 0.25mg Tablet with alcohol may make you sleepy and your breathing may become so shallow that you may not wake up. This may even lead to death.
People taking Clonofast 0.25mg Tablet in high doses or for a long term may become addicted to it. Also, people with a history of alcoholism and drug abuse are more likely to become addicted to Clonofast 0.25mg Tablet. Therefore, Clonofast 0.25mg Tablet should be taken for the shortest possible time and in the lowest effective dose.
No, do not stop taking Clonofast 0.25mg Tablet suddenly as you may experience withdrawal effects like depression, nervousness, difficulty in sleeping, irritability, sweating, upset stomach or diarrhea. Stopping it suddenly may even bring back the symptoms and make them harder to treat. You may also experience mood changes, anxiety, restlessness and changes in sleep patterns. These effects may occur even after taking low doses for a short period of time.
Yes, you should avoid taking foods containing caffeine such as tea, coffee, chocolates etc., while taking Clonofast 0.25mg Tablet. This is because caffeine stimulates your brain and Clonofast 0.25mg Tablet calms the brain. So, taking too much caffeine can affect the calming ability of this medicine and worsen your condition. Also, you should avoid taking alcohol while on treatment with Clonofast 0.25mg Tablet. Alcohol can cause excessive sleepiness and make you more drowsy and inattentive. Talk to your doctor if you have any other doubts regarding your diet while taking Clonofast 0.25mg Tablet.
Fact Box
Chemical Class
Benzodiazepines Derivative
Habit Forming
Yes
Therapeutic Class
NEURO CNS
Action Class
Benzodiazepines
References
- Stahl SM, editor. Clonazepam. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 137-41.
- McNamara JO. Pharmacotherapy of the Epilepsies. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 598-99.
- Porters RJ, Meldrum BS. Antiseizure Drugs. Sedative-Hypnotic Drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 415.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 301-303.
- Clonazepam. Roche; [revised Apr. 2009]. [Accessed 22 Mar. 2019] (online) Available from:
- Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Clonazepam. [Updated 2018 Oct 31]. [Accessed 20 Feb. 2020] (online) Available from:
- Clonazepam. Boucherville, Québec: Sandoz Canada Inc.; 2018. [Accessed 22 Mar. 2019] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 22 Mar. 2019] (online) Available from:
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Patient concerns
She has problem of epilepsy from last two years
Dr. Rahul Yadav
Paediatrics
Hello, epilepsy and seizures cannot be treated online without physically examining the child and detailed history.
anxiety high blood pressure sleep problems seizures
Dr. Jyoti Kapoor Madan
Psychiatry
Anxiety is the result of a hyperarousal state of nervous system due to a low threshold for threat perception. In simpler words, it's an ongoing flight or fight response. It can elicit a neuro-hormonal response understood as Flight or Fright reaction kicking in physiological cascade of symptoms ranging from palpitations, tachycardia, breathlessness, increased bowel movement, increase frequency of urination, dizziness, muscle tension or pain, trembling, dizziness, blurring of vision to restlessness, confusion and fainting spells. Chronic stress causes prolonged anxiety response with the consequences of slowed me ration, lack of concentration, headaches, fluctuations in blood pressure and increased wear and tear of body tissues. Identifying your stressors, learning to deal with them, de stressing regularly by doing something that makes one feel good, yoga and meditation are some non pharmacological strategies to deal with it. Siezures are due to electrophysiological disturbance in brain and anti convulsants are the treatment of choice. If the condition is persisting for a long time, it's better to see a psychiatrist.
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