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Clostran 9gm Sachet

Written By Dr. Betina Chandolia, MDS, BDS
Reviewed By Dr. Lalit Kanodia, MBA, MD Pharmacology
Last updated on 12 Nov 2024 | 01:07 AM (IST)
Clostran 9gm Sachet is used to lower cholesterol and to reduce the risk of heart disease. Cholesterol is a fatty substance that builds up in your blood vessels and causes narrowing, which may lead to a heart attack or stroke.
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General Information

Contains

Cholestyramine (4gm)

Marketer

Medi-Globe Corporation

Storage

Store below 30°C
The content is shown in English
Clostran 9gm Sachet image

Product introduction

Clostran 9gm Sachet may also be used to treat itching seen in certain types of liver disease and to relieve some types of diarrhea. This medicine may be used alone or in combination with other medicines. It may be taken with a meal or on an empty stomach. You can take it at any time of day but try to take it at the same time each day. Most people with high cholesterol do not feel ill, but if you stop taking this medicine, your condition could get worse. This may lead to your cholesterol levels creeping up again and increase your risk of heart disease and stroke.

It is important to have your cholesterol levels checked regularly. This medicine is only one part of a treatment program which should also include a healthy diet, regular exercise, smoking cessation, moderation of alcohol intake, and weight reduction. You can eat normally while taking this medicine, but try to avoid foods that are high in fat.

The most common side effect of this medicine is constipation. However, some patients may also experience nausea, vomiting, diarrhea, bloating, or indigestion. Before taking it, let your doctor know if you are suffering from any liver or kidney disease. Pregnant and breastfeeding women should consult the doctor before taking this medicine.

Uses of Clostran Sachet

Side effects of Clostran Sachet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Clostran
  • Indigestion
  • Nausea
  • Vomiting
  • Constipation

How to use Clostran Sachet

Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Empty the granules in a glass of water/milk, stir it and consume immediately. Clostran 9gm Sachet may be taken with or without food, but it is better to take it at a fixed time.

How Clostran Sachet works

Clostran 9gm Sachet is a bile acid binding agent. It removes bile acids from the body. The liver then produce more bile acids using cholesterol, as a result, the levels of cholesterol in the body is lowered.

Quick tips

  • Always take it with food and a full glass of water.
  • It may interfere with the absorption of vitamins such as A, D and K. Take supplements of these vitamins as suggested by your doctor.
  • It can delay or decrease the absorption of certain medicines. Any other medicine should be taken 1 hour before or 4 hours after taking Clostran 9gm Sachet.

Safety advice

Alcohol

Alcohol

CAUTION
Caution is advised when consuming alcohol with Clostran 9gm Sachet. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Clostran 9gm Sachet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Clostran 9gm Sachet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving

Driving

SAFE
Clostran 9gm Sachet does not usually affect your ability to drive.
Kidney

Kidney

SAFE IF PRESCRIBED
Clostran 9gm Sachet is safe to use in patients with kidney disease. No dose adjustment of Clostran 9gm Sachet is recommended.
However, talk to your doctor if you have any underlying kidney disease as the information available is very limited.
Liver

Liver

CONSULT YOUR DOCTOR
There is limited information available on the use of Clostran 9gm Sachet in patients with liver disease. Please consult your doctor.
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Frequently asked questions

You should not take Clostran 9gm Sachet if you have a blockage in your stomach or intestines. Consult your doctor in case of any doubts.
Clostran 9gm Sachet helps lower high cholesterol and thus the risk of heart diseases. If you stop taking this medicine, your blood cholesterol levels may increase again. Your doctor may advise you to follow a special diet and lifestyle to help prevent this from happening. Never stop taking this medicine without consulting your doctor.
Clostran 9gm Sachet works by binding to bile acid (fluid secreted by the liver ) in your intestines. Once it attaches to the bile acid, it forms a complex and is removed from your body. As a result of this, the bile acid levels are lowered which makes your liver convert more cholesterol into bile acid in order to replace what was lost. This lowers the amount of cholesterol in your body.
Constipation is a very common side effect of this medicine because of the way it works. Normally, bile acids in the intestine help control how much water is in your stool which in turn regulates your bowel movement. By binding to bile acid, this medication may remove some water in your stool, causing constipation. To get relief from constipation, increase your water intake and include fiber-rich food like green vegetables, fruits, cereals in your diet.
Cholesterol is a waxy fat, or lipid, which moves throughout your body in your blood. Your liver makes cholesterol, but you can also get it from foods. There are two types of cholesterol HDL (high-density lipoprotein) or the good cholesterol and LDL (low-density lipoprotein) or the bad cholesterol.
LDL or low-density lipoprotein is called bad cholesterol because it causes a buildup of cholesterol in the blood. This leads to blockage in the heart and is a direct cause of heart attacks, strokes, and peripheral artery disease.
HDL or high-density lipoprotein is also called as good cholesterol because it carries cholesterol from your blood to your liver to be removed. This reduces the risk of heart diseases.
You can book a lipid profile test with any accredited laboratory. This test helps you monitor your total cholesterol, LDL levels, HDL levels, triglycerides, and the ratio between cholesterol and HDL. You may need to fast for a period of 10-12 hours before giving your blood sample to the laboratory. After receiving your test report, consult a doctor to help you evaluate your test results.
Your total cholesterol level should be 125 to 200mg/dL, LDL should be less than 100mg/dL and HDL should be 40mg/dL or higher.
If you have a high cholesterol level, it builds upon the walls of your arteries. This condition causes arteries to become narrow, and the narrowed blood vessels reduce blood flow to the heart. This can lead to a heart attack or stroke.
Medication is typically prescribed when your cholesterol levels are high enough (LDL level greater than 190mg/dL) to increase your risk for heart disease or if you already have a history of a heart attack or stroke. Always consult your doctor before taking any medications.
Some of the most common symptoms of high cholesterol are chest pain, pain in the neck, jaw, upper abdomen, or back, extreme fatigue, difficulty breathing, numbness or coldness in your extremities.
Some of the foods with high cholesterol are red meat like lamb, pork, packaged food, fried foods, full-fat dairy, processed meat (sausage, bacon), etc.
Along with taking Clostran 9gm Sachet, taking a low-fat diet, regular exercise, reducing body weight, and limiting alcohol consumption can help improve the effectiveness of this medicine and lower cholesterol levels.

Fact Box

Chemical Class

Anion exchange resin

Habit Forming

No

Therapeutic Class

CARDIAC

Action Class

Bile Acid Sequestrants (BASs)

Related lab tests

Cholesterol - HDL

Cholesterol - LDL

Cholesterol - Total

References

  1. Bersot TP. Drug Therapy for Hypercholesterolemia and Dyslipidemia. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 898-99.
  2. Malloy MJ, Kane JP. Agents Used in Dyslipidemia. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 615-16.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 258.
  4. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Cholestyramine. [Updated 2018 Oct 31]. [Accessed 19 Feb. 2020] (online) Available from:
  5. Central Drugs Standard Control Organisation (CDSCO). Cholestyramine. [Accessed 15 Mar. 2019] (online) Available from:
  6. Cholestyramine [Product Information]. Spring Valley, NY: Par Pharmaceutical Inc; 2005. [Accessed 25 Jul. 2024] (online) Available from:
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User feedback

Twice A Day
39%
Once A Day
33%
Thrice A Day
28%
High cholesterol
67%
Others
33%
Average
100%
No Side Effect
100%
Empty stomach
100%
Expensive
67%
Average
33%

Patient concerns

High diabetes High cholesterol

Dr. Sanjay Bhatt
Dr. Sanjay Bhatt
Physician
Send reports Need to take medicineAnd what medicine are you taking alreadyA person can control his or her sugar levels by regular exercise and walk or regular aerobic exercises at least 30 to 45 minutes per day.MEDICAL NUTRITIONAL THERAPY THAT IS TO MAINTAIN CALORIES INTAKE AS PER BMI .TAKE HELP OF DIABETIC EDUCATOR. VISIT YOU DOCTOR AND LOW ALL WHAT DOCTOR SUGGESTED.IN TIME ALL ROUTINE INVESTIGATIONS SHOULD BE DONE.you souls not treat it as disease but start of a healthy life.Uncontrolled sugar levels for long time leads to lower limb weakness which is neuropathy and which is followed by foot ulcers and other complications.online prescription is not allowed without seeing pt.so contact doctor nearby for any change or dose adjustment or visit my clinic at gurgaon sector 52 RdCity snergy multi speciality clinic near SRS MARKET

I HAVE HIGH cholesterol. Cholesterol have in blood.

Dr. Sunil Sekhri
Dr. Sunil Sekhri
Diabetology
send lab reports copy
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Medi-Globe Corporation
Address: Medi-Globe Corporation , Headquarters , Medi-Globe-Str. 1-5 , 83101 Achenmühle - Germany

Vendor Details

Country of origin: India

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