Clozatab 50mg Tablet

Reviewed By Dr. Varun Gupta, MD Pharmacology, MBBS

Last updated on 28 Oct 2024 | 01:07 AM (IST)

Clozatab 50mg Tablet is used in the treatment of schizophrenia (a mental disorder that can result in hallucinations or delusions and also adversely affects a person’s ability to think and behave).

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General Information

Contains

Clozapine (50mg)

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Reliance Lifecare Pvt Ltd

Storage

Store below 30°C

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Product introduction

Clozatab 50mg Tablet may be taken with or without food. However, it is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration as advised by your doctor and if you have missed a dose, take it as soon as you remember. Do not skip any doses and finish the full course of treatment even if you feel better. It is important that this medication is not stopped suddenly without talking to your doctor as it may worsen your symptoms.

Some common side effects of this medicine include hypotension, dry mouth, headache, increased sweating, visual disturbance, and decreased blood pressure. Please consult your doctor if these side effects do not get better or worse.

Before taking this medicine it is important to inform your doctor if your suffering from high body temperature and muscle stiffness (neuroleptic malignant syndrome), have had abnormal tongue or face movements (dyskinesia), heart disease, diabetes, Parkinson’s disease, dementia, fits (epilepsy), difficulty in swallowing (dysphagia), or liver problems.

Uses of Clozatab Tablet

Schizophrenia

Benefits of Clozatab Tablet

Schizophrenia
Schizophrenia is a mental disorder in which a person’s thinking ability, feelings and behavior become abnormal. Clozatab 50mg Tablet helps restore the chemical imbalances in the brain that are responsible for such changes. It improves thoughts, behavior and enhances the quality of life.

Side effects of Clozatab Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Clozatab

Dizziness
Fainting
Constipation
Fever
Increased liver enzymes
Drowsiness
Seizure
Excessive salivation
Fast heart rate

How to use Clozatab Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Clozatab 50mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Clozatab Tablet works

Clozatab 50mg Tablet is an atypical antipsychotics. It works by modulating the action of certain chemical messengers in the brain that affects thoughts.

All substitutes for Clozatab 50mg Tablet

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Clozatab 50mg Tablet helps treat schizophrenia in people for whom other medicines are ineffective or not tolerated.
Take it with or without food, preferably at the same time everyday.
It can cause dizziness and sleepiness. Be cautious while driving or doing anything that requires concentration.
It may cause low blood pressure and dehydration. Drink plenty of fluids and rise slowly from a sitting or lying position.
It may increase your weight, blood sugar and cholesterol. Eat healthy, exercise regularly and monitor your blood levels regularly.
Your doctor may get regular blood tests done to monitor your blood cells during treatment with this medicine. Inform your doctor immediately if you notice any signs of infection such as fever, sore throat or rash.
Do not stop taking Clozatab 50mg Tablet without talking to your doctor first as it may cause worsening of symptoms.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Clozatab 50mg Tablet.

Pregnancy

SAFE IF PRESCRIBED

Clozatab 50mg Tablet is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Breast feeding

CONSULT YOUR DOCTOR

Clozatab 50mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

UNSAFE

Clozatab 50mg Tablet may cause side effects which could affect your ability to drive.

Kidney

CAUTION

Clozatab 50mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Clozatab 50mg Tablet may be needed. Please consult your doctor.

Liver

CAUTION

Clozatab 50mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Clozatab 50mg Tablet may be needed. Please consult your doctor.

Frequently asked questions

How long does it take for Clozatab 50mg Tablet to work?

Like many medicines, Clozatab 50mg Tablet does not work straight away. You might start feeling more calm and relaxed after a few weeks of taking this medicine.

Why has Clozatab 50mg Tablet been prescribed?

Clozatab 50mg Tablet is an antipsychotic drug used to treat manic episodes and Schizophrenia, a mood disorder. It shortens the time to recovery and prevents mania from returning. It is also used to reduce the risk of suicidal behavior in people with Schizophrenia.

Does Clozatab 50mg Tablet help with anxiety?

Yes, Clozatab 50mg Tablet helps calm the mind and decreases the level of anxiety and aggressive behavior in patients with Schizophrenia.

Is Clozatab 50mg Tablet addictive?

No, Clozatab 50mg Tablet is not addictive in nature. No habit-forming potential has been seen with its use. However, always follow your doctor's advice regarding the duration of its use.

When should I see my doctor?

Seek immediate medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction, pain or burning when you urinate, or vaginal itching or discharge.

Can Clozatab 50mg Tablet cause dizziness?

Yes. Clozatab 50mg Tablet can cause dizziness by reducing blood pressure. If this happens to you, you should sit or lie down until the symptoms pass. Always carry some sugary food or fruit juice with you in case you experience dizziness while traveling.

Why do I have to have regular blood tests while I am taking Clozatab 50mg Tablet?

Clozatab 50mg Tablet is known to cause a rare but serious side effect called “agranulocytosis”. This side effect occurs in less than 1 out of every 100 people who take this medicine. This side effect can result in a decrease in the number of white blood cells (infection-fighting cells) in your body. Without enough white blood cells, your body may not be able to. In order to prevent this, your doctor may prescribe you a blood test to check your white blood cell count.

Can I drink alcohol while taking Clozatab 50mg Tablet?

It is recommended that people taking this medicine should not drink alcohol. This is because Clozatab 50mg Tablet is an antipsychotic and taking it with alcohol can cause severe drowsiness. This can lead to falls and accidents. Also, drinking alcohol may make mania, depression, and anxiety worse. Discuss any concerns you have with your doctor, pharmacist, or nurse.

I am experiencing a change in my taste after the start of the treatment with Clozatab 50mg Tablet. Any tips to reduce it?

A change in taste is a common side-effect of this medicine. Rinse your mouth with a solution of salt and bicarbonate of soda before mealtimes to neutralize the bad taste in your mouth. You may also add some extra flavor or seasonings to your food.

I am having trouble remembering to take my medications. Is there anything I can do to help me remember?

In order to avoid missing a dose, use a calendar, pillbox, alarm clock, or cell phone alert to help you remember to take your medication. You may also ask a family member a friend to remind you or check in with you to be sure you are taking your medication.

What happens if I stop taking Clozatab 50mg Tablet?

It is advisable not to stop taking this medicine without talking to your doctor, since it may worsen your symptoms. Your doctor will probably want to decrease your dose gradually.

Fact Box

Chemical Class

Dibenzodiazepine Derivative

Habit Forming

Therapeutic Class

NEURO CNS

Action Class

Atypical Antipsychotics

References

Stahl SM, editor. Clozapine. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 153-59.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 308-309.
Clozapine. Potters Bar, Hertfordshire: Mylan Products Limited; 1989 [revised Dec. 2018]. [Accessed 22 Jan. 2019] (online) Available from:
Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 22 Mar. 2019] (online) Available from:
Clozapine. East Hanover, New Jersey: Novartis Pharmaceuticals; 2004. [Accessed 22 Mar. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 22 Mar. 2019] (online) Available from:
Clozapine [Patient Information Leaflet]. Ahmedabad, Gjjarat: Torrent Pharmaceuticals Ltd.; 2014. [Accessed 20 Feb. 2024] (online) Available from:

Patient concerns

Suffering Schizophrnia from last 20+ years. Is cure able ?

Dr. Ambrish Dharmadhikari

Psychiatry

We are here to helpSchizophrenia is chronic disorderSymptoms can be stopped from expressingCure is difficult word to say in schizophrenia

Suffering from schizophrenia . What to do

Dr. Mehtab Baig

Orthopaedic Physiotherapy

contacts your neurophysician or neuro psychtrist or some of meditation or exercises contact my clinic because of,this type of patient differ from others

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