Cofdex P Expectorant
Written By Dr. Sakshi Sharma, BDS
Reviewed By Dr. Lalit Kanodia, MBA, MD Pharmacology
Last updated on 11 Nov 2024 | 01:08 AM (IST)
Cofdex P Expectorant is a combination medicine used in the treatment of dry cough. It thins and loosens mucus in the nose, windpipe and lungs making it easier to cough out. It also narrows the small blood vessels and provides relief from congestion or stuffiness in the nose.
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General Information
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Product introduction
Cofdex P Expectorant is taken with or without food in a dose and duration as advised by the doctor. The dose you are given will depend on your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen. Let your healthcare team know about all other medications you are taking as some may affect, or be affected by this medicine.
The most common side effects are nausea, diarrhea, bloating, indigestion, headache, sweating, high blood pressure, insomnia, palpitations, skin rash, and stomach upset. Most of these are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any of these side effects. This medicine can also cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Avoid drinking alcohol while taking this medicine as it can worsen your sleepiness.
Never support self-medication or recommend your medicine to another person. Keep it out of reach of children. It is beneficial to have plenty of fluids while taking this medication. Before taking it, you should tell your doctor if you have liver diseases so that your doctor can prescribe a suitable dose for you. Pregnant or breastfeeding women should consult their doctor before taking this medicine.
The most common side effects are nausea, diarrhea, bloating, indigestion, headache, sweating, high blood pressure, insomnia, palpitations, skin rash, and stomach upset. Most of these are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any of these side effects. This medicine can also cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Avoid drinking alcohol while taking this medicine as it can worsen your sleepiness.
Never support self-medication or recommend your medicine to another person. Keep it out of reach of children. It is beneficial to have plenty of fluids while taking this medication. Before taking it, you should tell your doctor if you have liver diseases so that your doctor can prescribe a suitable dose for you. Pregnant or breastfeeding women should consult their doctor before taking this medicine.
Uses of Cofdex P Expectorant
Benefits of Cofdex P Expectorant
Dry cough
A dry cough is a cough where no phlegm or mucus is produced. It may cause a tickling sensation or itching in the throat and may be due to cold, flu, allergies or throat irritants. Cofdex P Expectorant suppresses severe dry cough and gives you relief from an itchy throat. Take it as prescribed by the doctor. Along with taking Cofdex P Expectorant, gargling with warm salt water and having ginger or honey can help you manage dry cough.
A dry cough is a cough where no phlegm or mucus is produced. It may cause a tickling sensation or itching in the throat and may be due to cold, flu, allergies or throat irritants. Cofdex P Expectorant suppresses severe dry cough and gives you relief from an itchy throat. Take it as prescribed by the doctor. Along with taking Cofdex P Expectorant, gargling with warm salt water and having ginger or honey can help you manage dry cough.
Side effects of Cofdex P Expectorant
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Cofdex P
- Nausea
- Diarrhea
- Bloating
- Indigestion
- Headache
- Dizziness
- Sweating
- High blood pressure
- Insomnia (difficulty in sleeping)
- Palpitations
- Skin rash
- Upset stomach
How to use Cofdex P Expectorant
Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. Cofdex P Expectorant may be taken with or without food, but it is better to take it at a fixed time.
How Cofdex P Expectorant works
Cofdex P Expectorant is a combination of three medicines: Phenylpropanolamine, Bromhexine and Dextromethorphan Hydrobromide. Phenylpropanolamine is a decongestant which narrows the small blood vessels providing relief from congestion or stuffiness in the nose. Bromhexine is a mucolytic which thins and loosens mucus (phlegm), making it easier to cough out. Dextromethorphan Hydrobromide is a cough suppressant that relieves cough by reducing the activity of cough centre in the brain.
Quick tips
- Cofdex P Expectorant is prescribed to get relief from a dry cough.
- Take exactly as directed by your doctor or on the label. Do not increase the dosage or take for longer than is recommended.
- Consult your doctor if you do not see any improvement and have a cough for more than 7 days.
- Let your doctor know if you are taking any anti-depressants.
- Inform your doctor if you have had a cough for a long time or if you have asthma or suffer from serious asthma attacks, or if your cough is accompanied by a fever, rash, or persistent headache.
Safety advice

Alcohol
CAUTION
Caution is advised when consuming alcohol with Cofdex P Expectorant. Please consult your doctor.

Pregnancy
CONSULT YOUR DOCTOR
Cofdex P Expectorant may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Cofdex P Expectorant during breastfeeding is not available. Please consult your doctor.

Driving
UNSAFE
Cofdex P Expectorant may cause side effects which could affect your ability to drive.

Kidney
SAFE IF PRESCRIBED
Cofdex P Expectorant is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Cofdex P Expectorant may not be needed in these patients. Please consult your doctor.

Liver
UNSAFE
Cofdex P Expectorant is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.
Fact Box
Habit Forming
No
Therapeutic Class
RESPIRATORY
References
- ScienceDirect. Phenylpropanolamine. [Accessed 22 Apr. 2019] (online) Available from:
- European Medicne Agency. Revised assessment report: Ambroxol and bromhexine containing medicinal products. 2015. [Accessed 01 Apr. 2019] (online) Available from:
- Drugs.com. Dextromethorphan Hydrobromide. [Accessed 05 Feb. 2019] (online) Available from:
- PubChem. Phenylpropanolamine. [Accessed 22 Apr. 2019] (online) Available from:
- ScienceDirect. Bromhexine. [Accessed 01 Apr. 2019] (online) Available from:
- ScienceDirect. Dextromethorphan Hydrobromide. [Accessed 01 Apr. 2019] (online) Available from:
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Patient concerns
I'm having this cough for about 2 weeks now, I have finished two bottles of cofdex but still no effect
Dr. Shubhra Chandhan Pradhan
ENT
It can be infected or allergy. May need antibiotics. Consult an ENT specialist nearby for proper clinical examination and diagnosis
Getting cough from last 10 days. Cough syrup Cofdex 2 bottel. Currently taking syrup Broxyl AP. Not getting relief. Pls inform any antibiotic if required. Thanks
Dr. Tapas Kumbhkar
Internal Medicine
Advise- x-ray ray chest
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