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Combiflam Tablet

Written By Dr. Shreya Gupta, MDS (Oral Pathology & Microbiology), BDS
Reviewed By Dr. Ashish Ranjan, MD (Pharmacology), MBBS
Last updated on 12 Nov 2024 | 01:03 AM (IST)
Combiflam Tablet contains two painkiller medicines. They work together to reduce pain, fever, and inflammation. It is used to treat many conditions such as headache, muscle pain, pain during periods, toothache, and joint pain.
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General Information

Contains

Ibuprofen (400mg)+ Paracetamol (325mg)

Marketer

Sanofi India Ltd

Storage

Store below 30°C
The content is shown in English
Combiflam Tablet image
Combiflam Tablet image
Combiflam Tablet image

Product introduction

Combiflam Tablet is best taken with food to reduce side effects. The dose and how often you need it will be decided by your doctor. You should take it regularly as advised by your doctor. Medicines used to treat pain are usually best taken at the first sign of pain. It is meant for short-term use only. Consult your doctor if the symptoms persist or worsen or if the medicine is required for use beyond 3 days.

Side effects are rare if this medicine is used correctly but it may cause heartburn, indigestion, nausea, vomiting, headache, and stomach pain. Consult your doctor if any of these bother you or do not go away.

This medicine is widely prescribed and considered safe but may not be suitable for everybody. Before taking it, let your doctor know if you drink a lot of alcohol, are using blood-thinning medicines, or have asthma or any liver or kidney problems. It may affect the dose or suitability of this medicine. Pregnant or breastfeeding women should also consult their doctor before using it. Let your doctor know about all the other medicines you are taking because they may affect, or be affected by, this medicine. It is best to avoid drinking alcohol while using this medicine.

Uses of Combiflam Tablet

Benefits of Combiflam Tablet

Pain relief
Combiflam Tablet contains two medicines: Paracetamol and Ibuprofen both of which are widely used as pain killers. They work in different ways to reduce pain, swelling, and inflammation. This medicine is very effective in treating mild to moderate pain associated with migraine, headache, backache, period (menstrual) pain, dental pain, and rheumatic and muscular pain. The anti-inflammatory component makes this medicine more effective in treating strains, sprains, and muscle pains.

Take it as it is prescribed to get the most benefit. Do not take too much as this can be dangerous and do not take it for longer than you need it. In general, you should take the lowest dose that works, for the shortest possible time.
Treatment of Fever
Combiflam Tablet helps lower high temperature caused by fever. This medicine is effective in treating cold and flu symptoms, sore throat, and fever. Take it as it is prescribed to get the most benefit. Do not take too much or for longer than you need as this can be dangerous. In general, you should take the lowest dose that works, for the shortest possible time.

Side effects of Combiflam Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Combiflam
  • Heartburn
  • Indigestion
  • Nausea
  • Stomach pain
  • Vomiting
  • Headache
  • Sleepiness

How to use Combiflam Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Combiflam Tablet is to be taken with food.

How Combiflam Tablet works

Combiflam Tablet is a combination of two medicines: Ibuprofen and Paracetamol. It works by blocking the release of certain chemical messengers that cause fever, pain and inflammation (redness and swelling).

All substitutes for Combiflam Tablet

For information purposes only. Consult a doctor before taking any medicine.

Flexon Tablet

by Aristo Pharmaceuticals Pvt Ltd
₹1.55/tablet
24% cheaper
<h3 class=bodySemiBold>Flexon Tablet</h3>

Fenceta 400mg/325mg Tablet

by Alkem Laboratories Ltd
₹1.59/tablet
22% cheaper
<h3 class=bodySemiBold>Fenceta 400mg/325mg Tablet</h3>

Duoflam P 400mg/325mg Tablet

by Maneesh Pharmaceuticals Ltd
₹1.81/tablet
11% cheaper
<h3 class=bodySemiBold>Duoflam P 400mg/325mg Tablet</h3>

Buflam Plus Tablet

by Ornate Labs Pvt Ltd
₹1.16/tablet
43% cheaper
<h3 class=bodySemiBold>Buflam Plus Tablet</h3>

Rubigesic P 400 mg/325 mg Tablet

by Bevit Pharmaceuticals Ltd
₹3.86/tablet
90% costlier
<h3 class=bodySemiBold>Rubigesic P 400 mg/325 mg Tablet</h3>

Quick tips

  • You have been prescribed this combination medicine to relieve pain, inflammation, and fever.
  • Take it with food to avoid getting an upset stomach.
  • Take it as per the dose and duration prescribed by your doctor. Long-term use may lead to stomach bleeding and kidney problems.
  • Avoid consuming alcohol when taking Combiflam Tablet as it may cause excessive drowsiness and increase the risk of liver damage.
  • Do not take it with any other medicine containing paracetamol (drugs for pain/fever or cough and cold) without asking your doctor first.

Safety advice

Alcohol

Alcohol

UNSAFE
It is unsafe to consume alcohol with Combiflam Tablet.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Combiflam Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Combiflam Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving

Driving

UNSAFE
Combiflam Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney

Kidney

CAUTION
Combiflam Tablet should be used with caution in patients with kidney disease. Dose adjustment of Combiflam Tablet may be needed. Please consult your doctor.
Liver

Liver

CAUTION
Combiflam Tablet should be used with caution in patients with liver disease. Dose adjustment of Combiflam Tablet may be needed. Please consult your doctor.
However, the use of Combiflam Tablet is not recommended in patients with severe liver disease and active liver disease.

Frequently asked questions

Combiflam Tablet is safe for most patients. However, in some patients, it may cause some unwanted side effects like nausea, vomiting, stomach pain, heartburn and diarrhea. Inform your doctor if you experience any persistent problem due to this medication.
Combiflam Tablet should be continued as advised by your doctor, if you are using the medicine for a condition associated with long-term pain. It can be discontinued if you are using it for short-term pain relief.
Yes, the use of Combiflam Tablet may cause nausea and vomiting. Taking it with milk, food or antacids can prevent nausea. Avoid taking fatty or fried foods along with this medication. In case of vomiting, drink plenty of water or other fluids by taking small frequent sips. Talk to your doctor if vomiting persists and you notice signs of dehydration, like dark colored and strong-smelling urine or a low frequency of urination. Do not take any other medicines without speaking to your doctor.
Yes, the use of Combiflam Tablet can cause dizziness (feeling faint, weak, unsteady or lightheaded) in some patients. If you feel dizzy or lightheaded, do not drive or use any machines. It is better to rest for sometime and resume once you feel better.
The use of Combiflam Tablet is considered to be harmful for patients with known allergy to any of the components of this medicine. It should be avoided in patients with known allergy to other painkillers (NSAIDs). The use of this medicine should preferably be avoided in patients with a history of stomach ulcers or in patients with active or recurrent stomach ulcer/bleeding. It should also be avoided in patients with history of heart failure, high blood pressure, and liver or kidney disease.
No, Combiflam Tablet should not be taken for stomach pain without consulting a physician. This drug can increase stomach acid secretion which may aggravate an unknown underlying condition.
Yes, the long-term use of Combiflam Tablet can cause damage to the kidneys. Normal kidneys produce a chemical called prostaglandins that protect the kidneys from damage. Use of painkillers lowers the levels of prostaglandins in the body, leading to kidney damage because of long-term use. Therefore, the use of painkillers is not recommended in patients with underlying kidney disease.
No, taking a higher than the recommended dose of Combiflam Tablet can increase the risks of side effects like nausea, vomiting, heartburn, indigestion and diarrhea. In fact, using this medicine for a long-term can also damage your kidneys on long-term use. If you are experiencing increased severity of pain or if the pain is not relieved by the recommended doses of this medicine, please consult your doctor for re-evaluation.

Fact Box

Habit Forming

No

Therapeutic Class

PAIN ANALGESICS

Related lab tests

Complete Blood Count

References

  1. ScienceDirect. Paracetamol/Acetaminophen. [Accessed 23 Apr. 2019] (online) Available from:
  2. Acetaminophen and ibuprofen [Prescribing Information]. Greenville, NC: Catalent Greenville Inc.; 2023. [Accessed 14 Aug. 2024] (online) Available from:
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User feedback

Once A Day
42%
Twice A Day
36%
Thrice A Day
22%
Fever
36%
Headache
34%
Others
12%
Dental pain
10%
Pain during menstruation
7%
Excellent
39%
Average
38%
Poor
23%
No Side Effect
72%
Liver damage
8%
Abdominal pain
4%
Constipation
4%
Allergic reaction
4%
With or without food
72%
Empty stomach
22%
With food
6%
Not Expensive
51%
Average
29%
Expensive
20%

Patient concerns

Fever from yesterday night which is causes mild cold body pain

Dr. Pushkar Mani
Dr. Pushkar Mani
Physician
take combiflam one tablet sos

Slight fever and pain in joints

Dr. Pushkar Mani
Dr. Pushkar Mani
Physician
Combiflam twice daily for 3 days
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Sanofi India Ltd
Address: Sanofi House, CTS No.117-B, L&T Business Park, Saki Vihar Road, Powai, Mumbai 400072

Vendor Details

Country of origin: India

Lab tests offered by us

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