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Cycram 1000mg Injection

Written By Dr. Radhika Dua, MDS, BDS
Reviewed By Dr. Shilpa Garcha, MD (Pharmacology), MBBS
Last updated on 08 Oct 2024 | 07:43 PM (IST)
Cycram 1000mg Injection is used in the treatment of different kinds of cancers. It is also used to treat kidney disease known as nephrotic syndrome in children after other treatments have not worked. It may be also used to treat other conditions, as determined by the doctor.
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General Information

Contains

Cyclophosphamide (1000mg)

Marketer

Vhb Life Sciences Inc

Storage

Store in a refrigerator (2 - 8°C). Do not freeze.
The content is shown in English
Cycram 1000mg Injection image

Product introduction

Cycram 1000mg Injection is given as an injection into a vein by the healthcare professional, but better if injected at the same time every day. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

The most common side effects of this medicine include vomiting, nausea, hair loss, fever, and blood in urine. If they do not go away or get worse, tell your doctor. There may be ways of preventing or reducing these effects. It is very strong medicine and some people may develop serious side effects while taking it. This medicine may lower your ability to fight infections and lead to problems with your blood, liver or kidneys. Your doctor will advise you regular blood tests to check for these. It is advised that you drink extra fluids so that you pass more urine. This will help prevent bladder and kidney problems and keep your kidneys working well.

Before taking it, tell your doctor if you have liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Uses of Cycram Injection

Side effects of Cycram Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Cycram
  • Hair loss
  • Nausea
  • Infection
  • Diarrhea
  • Vomiting
  • Decreased white blood cell count (neutrophils)
  • Decreased white blood cell count (lymphocytes)
  • Myelosuppression
  • Cystitis
  • Microhematuria

How to use Cycram Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Cycram Injection works

Cycram 1000mg Injection is an anti-cancer medication. It is an alkylating agent which works by damaging the genetic material (DNA and RNA) of the cancer cells, thereby stopping their growth and multiplication. This is how it works against cancer.

All substitutes for Cycram 1000mg Injection

For information purposes only. Consult a doctor before taking any medicine.

Cycloxan 1000mg Injection

by Biochem Pharmaceutical Industries
₹158.3/injection
51% costlier
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Chophos 1000mg Injection

by Intas Pharmaceuticals Ltd
₹150/injection
43% costlier
<h3 class=bodySemiBold>Chophos 1000mg Injection</h3>

Phosmid 1000mg Injection

by Neon Laboratories Ltd
₹79/injection
25% cheaper
<h3 class=bodySemiBold>Phosmid 1000mg Injection</h3>

Oncomide 1000mg Injection

by Khandelwal Laboratories Pvt Ltd
₹100.77/injection
4% cheaper
<h3 class=bodySemiBold>Oncomide 1000mg Injection</h3>

Cyphos 1000mg Injection

by Getwell Pharma (I) Pvt Ltd
₹108/injection
3% costlier
<h3 class=bodySemiBold>Cyphos 1000mg Injection</h3>

Quick tips

  • Cycram 1000mg Injection helps in the treatment of cancer.
  • It is injected into the vein by a doctor or healthcare professional.
  • Drink plenty of fluids or urinate frequently to prevent urinary problems while taking this medication.
  • Your doctor may get regular blood tests to monitor your blood counts while on treatment with this medication.
  • You are more likely to get sick or heal slower while taking this medication. Talk to your doctor before getting any vaccines.
  • Contact your doctor immediately if you experience difficulty in urinating or blood in urine while on treatment with this medication.
  • Do not take Cycram 1000mg Injection if you are pregnant or breastfeeding.
  • Use effective contraception method to prevent pregnancy while taking this medicine.
  • Cycram 1000mg Injection helps in the treatment of cancer.
  • Drink plenty of fluids or urinate frequently to prevent urinary problems while taking this medication.
  • Take it with food if you experience irritation of the stomach, preferably in the morning.
  • Your doctor may get regular blood tests to monitor your blood counts while on treatment with this medication.
  • You are more likely to get sick or heal slower while taking this medication. Talk to your doctor before getting any vaccines.
  • Contact your doctor immediately if you experience difficulty in urinating or blood in urine while on treatment with this medication.
  • Do not take Cycram 1000mg Injection if you are pregnant or breastfeeding.
  • Use effective contraception method to prevent pregnancy while taking this medicine.

Safety advice

Alcohol

Alcohol

UNSAFE
It is unsafe to consume alcohol with Cycram 1000mg Injection.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Cycram 1000mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding

Breast feeding

UNSAFE
Cycram 1000mg Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving

Driving

UNSAFE
Cycram 1000mg Injection may cause side effects which could affect your ability to drive.
Cycram 1000mg Injection may cause undesirable effects (e.g., dizziness, blurred vision, visual impairment) which could affect the ability to drive.
Kidney

Kidney

CAUTION
Cycram 1000mg Injection should be used with caution in patients with severe kidney disease. Dose adjustment of Cycram 1000mg Injection may be needed. Please consult your doctor.
Liver

Liver

CAUTION
Cycram 1000mg Injection should be used with caution in patients with liver disease. Dose adjustment of Cycram 1000mg Injection may be needed. Please consult your doctor.

Frequently asked questions

Yes, Cycram 1000mg Injection can cause infertility in both men and women. It may interfere with the normal menstrual cycle in women and may stop sperm production in men. If you are considering becoming parents after the treatment please discuss this with your doctor. Talk to your doctor about cryopreservation (freezing) of sperm or eggs prior to treatment because of the possibility of irreversible infertility due to therapy with Cycram 1000mg Injection.
No, there is no evidence that you need to avoid sun exposure while on Cycram 1000mg Injection. Skin and nail discoloration are reported rarely with Cycram 1000mg Injection.
Cancer medicines and radiation therapy can increase the risk of developing other cancers. These may not develop soon and may take a number of years after the completion of your treatment. The risk of developing cancer with Cycram 1000mg Injection is high in the urinary bladder. Other rare cancers that may occur with use of Cycram 1000mg Injection include Acute leukemia, Myelodysplastic syndrome, and cancer of the ureters.
Yes, Cycram 1000mg Injection is a chemotherapy medicine, it belongs to the class of alkylating agents. It works by killing cancer cells. It is also known as cytotoxic medicine.
Yes, Cycram 1000mg Injection can be used to treat nephrotic syndrome (a disease that is caused by damage to the kidneys) in children whose disease has not improved, has gotten worse, or has come back after taking other medications. Along with that, it can be used in children who experienced intolerable side effects with other medications. However, in adults, the safety and effectiveness of Cycram 1000mg Injection for nephrotic syndrome has not been established.
Yes, Cycram 1000mg Injection may cause weight loss because of reduced appetite. This reduction in weight could be due to underlying cancer. Consult your doctor, if weight loss is worrying you.
Yes, Cycram 1000mg Injection can cause infertility in both men and women. It may interfere with the normal menstrual cycle in women and may stop sperm production in men. If you are considering becoming parents after the treatment please discuss this with your doctor. Talk to your doctor about cryopreservation (freezing) of sperm or eggs prior to treatment because of the possibility of irreversible infertility due to therapy with Cycram 1000mg Injection.
No, there is no evidence that you need to avoid sun exposure while on Cycram 1000mg Injection. Skin and nail discoloration are reported rarely with Cycram 1000mg Injection.
Cancer medicines and radiation therapy can increase the risk of developing other cancers. These may not develop soon and may take a number of years after the completion of your treatment. The risk of developing cancer with Cycram 1000mg Injection is high in the urinary bladder. Other rare cancers that may occur with use of Cycram 1000mg Injection include Acute leukemia, Myelodysplastic syndrome, and cancer of the ureters.
Yes, Cycram 1000mg Injection is a chemotherapy medicine, it belongs to the class of alkylating agents. It works by killing cancer cells. It is also known as cytotoxic medicine.
Yes, Cycram 1000mg Injection can be used to treat nephrotic syndrome (a disease that is caused by damage to the kidneys) in children whose disease has not improved, has gotten worse, or has come back after taking other medications. Along with that, it can be used in children who experienced intolerable side effects with other medications. However, in adults, the safety and effectiveness of Cycram 1000mg Injection for nephrotic syndrome has not been established.
Yes, Cycram 1000mg Injection may cause weight loss because of reduced appetite. This reduction in weight could be due to underlying cancer. Consult your doctor, if weight loss is worrying you.

Fact Box

Chemical Class

Nitrogen Mustard Compounds

Habit Forming

No

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Alkylating agent

Related lab tests

Prothrombin Time

Triglycerides

Urine Albumin

References

  1. Lake DF, Briggs AD, Akporiaye ET. Immunopharmacology. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 975.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 335-38.
  3. Cyclophosphamide monohydrate. Camberley, Surrey: Sandoz Limited; 2014 [revised 07 Jun. 2017]. [Accessed 26 Mar. 2019] (online) Available from:
  4. Cyclophosphamide. Baxter Health Corporation; 1959. [Accessed 26 Mar. 2019] (online) Available from:
  5. Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 26 Mar. 2019] (online) Available from:
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Patient concerns

nephrotic syndrome protein in urine

Dr. Deepak Kumar Soni
Dr. Deepak Kumar Soni
Ayurveda
Hi Kindly consult to your nearest Ayurvedic doctor Need to take proper treatment

Nephrotic syndrome since December 2009

Dr. Vikas Sharma
Dr. Vikas Sharma
Neurology
Show to kidney
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Vhb Life Sciences Inc
Address: 50-AB, Government Industrial Estate, Charkop Naka, Kandivali West , Mumbai - 400067, Maharashtra, India

Vendor Details

Country of origin: India

Lab tests offered by us

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