D-Venizep 100 Tablet ER
Written By Dr. Swati Mishra, BDS
Reviewed By Dr. Ashish Ranjan, MD (Pharmacology), MBBS
Last updated on 12 Nov 2024 | 01:08 AM (IST)
D-Venizep 100 Tablet ER is a combination of two medicines used in the treatment of depression. This medicine helps by increasing the level of chemical messengers in the brain that have a calming effect on the brain and relax the nerves, thus treating your depression.
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General Information
Contains
Desvenlafaxine (100mg)+ Clonazepam (0.5mg)
Marketer
Sun Pharmaceutical Industries Ltd
Storage
Store below 30°C
The content is shown in English


Product introduction
D-Venizep 100 Tablet ER may be taken with or without food, preferably at the same time each day. Take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration as advised by your doctor and if you have missed a dose, take it as soon as you remember it. Do not skip any doses and finish the full course of treatment even if you feel better. It is important that this medication is not stopped suddenly without talking to your doctor as it may worsen your symptoms.
Some common side effects of this medicine include nausea, constipation, confusion, insomnia (difficulty in sleeping), memory impairment, headache, ejaculation disorder, tiredness, erectile dysfunction, low sexual desire, and uncoordinated body movements. It may also cause dizziness and sleepiness, do not drive or do anything that requires mental focus until you know how this medicine affects you. However, these are temporary and usually resolve on their own. Please consult your doctor if these do not subside or bother you.
Before taking it, inform your doctor if you are suffering from thyroid or kidney disease, epilepsy, Parkinson’s disease, glaucoma, or any heart disease. You should not take this medicine if you are under the influence of alcohol or any sleep-inducing, cough, and/ or allergy medication. You should avoid alcohol while taking D-Venizep 100 Tablet ER, as it may worsen certain side effects.
Some common side effects of this medicine include nausea, constipation, confusion, insomnia (difficulty in sleeping), memory impairment, headache, ejaculation disorder, tiredness, erectile dysfunction, low sexual desire, and uncoordinated body movements. It may also cause dizziness and sleepiness, do not drive or do anything that requires mental focus until you know how this medicine affects you. However, these are temporary and usually resolve on their own. Please consult your doctor if these do not subside or bother you.
Before taking it, inform your doctor if you are suffering from thyroid or kidney disease, epilepsy, Parkinson’s disease, glaucoma, or any heart disease. You should not take this medicine if you are under the influence of alcohol or any sleep-inducing, cough, and/ or allergy medication. You should avoid alcohol while taking D-Venizep 100 Tablet ER, as it may worsen certain side effects.
Uses of D-Venizep Tablet ER
Benefits of D-Venizep Tablet ER
Treatment of Depression
D-Venizep 100 Tablet ER helps in maintaining the balance of certain chemicals in the brain that affect mood and behavior. This improves your mood, relieves anxiety, tension, helps you sleep better and increases your energy levels. D-Venizep 100 Tablet ER prevents extreme changes in mood and helps you feel less agitated. You may experience fewer episodes of depression and low mood.
It can take several weeks for this medicine to work and you may still feel low during this time. It is likely that you will take this medicine for at least six months but possibly much longer. It needs to be taken regularly to work effectively. Do not stop taking it unless your doctor tells you to.
D-Venizep 100 Tablet ER helps in maintaining the balance of certain chemicals in the brain that affect mood and behavior. This improves your mood, relieves anxiety, tension, helps you sleep better and increases your energy levels. D-Venizep 100 Tablet ER prevents extreme changes in mood and helps you feel less agitated. You may experience fewer episodes of depression and low mood.
It can take several weeks for this medicine to work and you may still feel low during this time. It is likely that you will take this medicine for at least six months but possibly much longer. It needs to be taken regularly to work effectively. Do not stop taking it unless your doctor tells you to.
Side effects of D-Venizep Tablet ER
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of D-Venizep
- Nausea
- Constipation
- Confusion
- Insomnia (difficulty in sleeping)
- Memory impairment
- Headache
- Ejaculation disorder
- Tiredness
- Erectile dysfunction
- Low sexual desire
- Uncoordinated body movements
- Depression
How to use D-Venizep Tablet ER
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. D-Venizep 100 Tablet ER may be taken with or without food, but it is better to take it at a fixed time.
How D-Venizep Tablet ER works
D-Venizep 100 Tablet ER is a combination of two medicines:.
Quick tips
- You have been prescribed D-Venizep 100 Tablet ER for the treatment of depression.
- Inform your doctor immediately if you get thoughts about harming yourself or ending your life.
- It is also advisable to inform your doctor if you get aggressive, anxiety, trouble sleeping, an increase in activity or talking more than what is normal for you, and other unusual changes in behavior or mood.
- Do not stop taking D-Venizep 100 Tablet ER unless your doctor tells you to do so. Stopping treatment suddenly can cause problems and your doctor will probably want you to reduce your dose gradually when this becomes necessary.
- Inform your doctor if you are taking any other antidepressants.
- If you have hypertension, monitor your blood pressure regularly while taking D-Venizep 100 Tablet ER.
- Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress.
- You have been prescribed D-Venizep 100 Tablet ER for the treatment of depression.
- Inform your doctor immediately if you get thoughts about harming yourself or ending your life.
- It is also advisable to inform your doctor if you get aggressive, anxiety, trouble sleeping, an increase in activity or talking more than what is normal for you, and other unusual changes in behavior or mood.
- Do not stop taking D-Venizep 100 Tablet ER unless your doctor tells you to do so. Stopping treatment suddenly can cause problems and your doctor will probably want you to reduce your dose gradually when this becomes necessary.
- Inform your doctor if you are taking any other antidepressants.
- If you have hypertension, monitor your blood pressure regularly while taking D-Venizep 100 Tablet ER.
- Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress.
Safety advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with D-Venizep 100 Tablet ER.

Pregnancy
CONSULT YOUR DOCTOR
D-Venizep 100 Tablet ER is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding
CONSULT YOUR DOCTOR
D-Venizep 100 Tablet ER is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving
UNSAFE
D-Venizep 100 Tablet ER may cause side effects which could affect your ability to drive.

Kidney
SAFE IF PRESCRIBED
D-Venizep 100 Tablet ER is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of D-Venizep 100 Tablet ER may not be needed in these patients. Please consult your doctor.
Use of D-Venizep 100 Tablet ER can cause excessive sleepiness in patients with end stage kidney disease.
Use of D-Venizep 100 Tablet ER can cause excessive sleepiness in patients with end stage kidney disease.

Liver
CAUTION
D-Venizep 100 Tablet ER should be used with caution in patients with liver disease. Dose adjustment of D-Venizep 100 Tablet ER may be needed. Please consult your doctor.
Frequently asked questions
During the first few months of treatment, D-Venizep 100 Tablet ER may increase suicidal thoughts or actions in some patients. Patients having mood or behavioral disorder have a high risk of developing suicidal thoughts and actions. You should pay close attention and report your doctor of any such behavior or mood changes. Make sure that you visit the doctor for the scheduled follow-up appointments.
No, you should continue to take D-Venizep 100 Tablet ER even if you feel well. If you stop D-Venizep 100 Tablet ER suddenly, serious withdrawal symptoms may occur. Your doctor will probably decrease your dose gradually.
There are reports that suggest association of weight gain with the use of D-Venizep 100 Tablet ER. If you maintain good eating habits and exercise regularly, you might not gain any weight. An important point to remember is that it is easier to stop weight gain than losing increased weight.
Yes, D-Venizep 100 Tablet ER can make you feel sleepy. Avoid driving, operating machinery, working at heights or participating in potentially dangerous activities until you know how this medicine affects you.
The use of D-Venizep 100 Tablet ER can cause sexual side effects in both men and women. Most commonly caused problems are decreased sexual desire, erectile dysfunction (inability to develop or maintain the erection during the sexual activity) and inability to reach orgasm. It can also cause a decrease in satisfaction and cause discomfort while having sex. If you experience these problems, discuss with your doctor.
No, do not drink alcohol while you are taking D-Venizep 100 Tablet ER. Drinking alcohol can increase the severity of drowsiness or sleepiness caused by D-Venizep 100 Tablet ER.
Everybody responds differently to the treatment. In general, it can take several weeks to feel the full benefits of D-Venizep 100 Tablet ER, although some people may start to feel better sooner. When taking D-Venizep 100 Tablet ER, it is important to give it time to work.
Keep this medicine in the packet or the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
Fact Box
Habit Forming
Yes
Therapeutic Class
NEURO CNS
References
- Desvenlafaxine. Philadelphia, Pennsylvania: Wyeth Pharmaceuticals; 2008 [revised Jul. 2011]. [Accessed 23 Apr. 2019] (online) Available from:
- Clonazepam. Boucherville, Québec: Sandoz Canada Inc.; 2018. [Accessed 23 Apr. 2019] (online) Available from:
- MedlinePlus. Desvenlafaxine. [Accessed 23 Apr. 2019] (online) Available from:
- Clonazepam. Boucherville, Québec: Sandoz Canada Inc.; 2018. [Accessed 23 Apr. 2019] (online) Available from:
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User feedback
Once A Day
90%
Twice A Day
10%
Depression
80%
Others
20%
Excellent
50%
Average
50%
Insomnia (difficulty in sleeping)
50%
Dizziness
50%
With food
100%
Patient concerns
I am suffering. from fatty liver and mild prostatic enlargements. please suggest medicine I am taking me fine for mental. Problem Medicine are Lamez of. 200, d venizep 50 and lithium 400
Dr. Jyoti Kapoor Madan
Psychiatry
For prostate- consult a urologist For fatty liver- consult a gastroenterologist Rest is treatment of bipolar disorder and you need follow up with your psychiatrist.
I do not get sleep in nights due to which Iam taking D-VENIZEP 100 is there any side effects how long i have to take Is there any days to follow. Please suggest what action I have to take as I heard that we should not use sleeping pills or medical tablets its due to we habbitate and will effect the health please correct me
Dr. Jyoti Kapoor Madan
Psychiatry
D Veniz is not a sleeping pill. It is an antidepressant. Antidepressants are non addictive but frequent follow up with your psychiatrist is mandatory. Based on your clinical history, your doctor plans the type of medicine and it's dose and duration. For first episode of anxiety/ depression/ panic, the usual maintenance phase is 6 months of asymptomatic period, after which medicines can be gradually tapered. But treatment may need to continue longer depending on severity and frequency of episodes. To take any decision to change medication or stop them, several factors have to be taken in account for which regular follow up with your psychiatrist is important. For second opinion, seek a proper consultation with another psychiatrist and take along your previous prescriptions.
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Marketer details
Name: Sun Pharmaceutical Industries Ltd
Address: Plot no 107/108,Namli block , Ranipool, East Sikkim 737135
Address: Plot no 107/108,Namli block , Ranipool, East Sikkim 737135
Vendor Details
Country of origin: India
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