Dabazine 100 Injection

Reviewed By Dr. Shilpa Garcha, MD (Pharmacology), MBBS

Last updated on 22 Oct 2024 | 01:04 AM (IST)

Dabazine 100 Injection is used in the treatment of cancers of lymphatic system and malignant melanoma (a type of skin cancer). It may be also used to treat other conditions, as determined by the doctor.

Genuine

Authenticity Assured

Prescription

required

Cold stored

Stored between 2-8°C

MRP ₹322

General Information

Contains

Dacarbazine (100mg)

Marketer

Axiommax Oncology Pvt Ltd

Storage

Store in a refrigerator (2 - 8°C). Do not freeze.

The content is shown in English

Product introduction

Dabazine 100 Injection is given as an injection into a vein by the healthcare professional, but better if injected at the same time every day. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

The most common side effects of this medicine include nausea, vomiting, and decreased white blood cell count, and injection site pain,. If they do not go away or get worse, tell your doctor. There may be ways of preventing or reducing these effects. It is very strong medicine and some people may develop serious side effects while taking it. This medicine may lower your ability to fight infections and lead to problems with your blood, liver or kidneys. Inform your doctor if you notice unusual bleeding or bruising, lack of energy, loss of appetite, and yellowing of eyes. Your doctor will advise you regular blood tests to check for these.

Before taking it, tell your doctor if you have liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Uses of Dabazine Injection

Benefits of Dabazine Injection

Malignant melanoma
Malignant melanoma is a type of skin cancer that develops in melanocytes, the cells that produce the pigment called melanin. Melanin is the pigment that gives the skin its color. Malignant melanoma is the most deadly and aggressive kind of skin cancer. Dabazine 100 Injection sticks to the genetic code, called DNA,of the cancer cells and kills them . It also prevents their growth and further spread. This helps to treat the cancer.

Hodgkin’s disease
Hodgkin’s disease is a type of lymphoma, which is a blood cancer that starts in the lymphatic system. The lymphatic system helps the immune system get rid of waste and fight infections. Dabazine 100 Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. Follow your doctor’s instructions carefully.

Side effects of Dabazine Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Dabazine

Nausea
Vomiting
Injection site pain
Decreased white blood cell count
Loss of appetite

How to use Dabazine Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Dabazine Injection works

Dabazine 100 Injection is an anti-cancer medication. It works by damaging the genetic material (DNA and RNA) of the cancer cells. This stops their growth and multiplication.

Quick tips

Dabazine 100 Injection is given as an injection into veins under the supervision of a doctor.

Safety advice

Alcohol

CAUTION

Caution is advised when consuming alcohol with Dabazine 100 Injection. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Dabazine 100 Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Dabazine 100 Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

UNSAFE

Dabazine 100 Injection may cause side effects which could affect your ability to drive.
Dabazine 100 Injection may influence the ability to drive because of its central nervous system side effects.

Kidney

CAUTION

Dabazine 100 Injection should be used with caution in patients with kidney disease. Dose adjustment of Dabazine 100 Injection may be needed. Please consult your doctor.

Liver

CAUTION

Dabazine 100 Injection should be used with caution in patients with liver disease. Dose adjustment of Dabazine 100 Injection may be needed. Please consult your doctor.

Frequently asked questions

How is Dabazine 100 Injection administered?

Dabazine 100 Injection is administered as infusion or injection. Absorption by mouth is slow and varies, therefore, intravenous (given through vein) infusion or injection administration is preferred.

Is Dabazine 100 Injection a vesicant?

Dabazine 100 Injection is a potent vesicant (it is corrosive), and it should be carefully administered to avoid the risk of extravasation (leaking into the tissues).

What is Dabazine 100 Injection used for?

Dabazine 100 Injection is used to treat skin cancer that has spread to other parts of the body (malignant melanoma), cancer of the white blood cell (Hodgkin's lymphoma) and advanced adult soft tissue sarcomas (cancer of soft tissues such as muscles, tendons, fat, and blood vessels).

How effective is Dabazine 100 Injection?

Dabazine 100 Injection is effective if taken at recommended dosage and duration as advised by your doctor.

Does Dabazine 100 Injection cause hair loss?

Yes, hair loss is a common side effect of Dabazine 100 Injection.

Fact Box

Chemical Class

Triazene Derivative

Habit Forming

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Alkylating agent

References

Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1686-87.
Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 942.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 346-47.
Dacarbazine citrate. Wedel, Germany: medac GmbH; 1997 [revised Jan. 2017]. [Accessed 26 Mar. 2019] (online) Available from:
Drugs.com. Dacarbazine Pregnancy and Breastfeeding Warnings. [Accessed 26 Mar. 2019] (online) Available from:
Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Dacarbazine. [Updated 2018 Dec 3]. [Accessed 18 Feb. 2020] (online) Available from:

Patient concerns

Brain star tablet for which disice

Dr. Vikas Sharma

Neurology

For neuroleptic malignant syndrome

if any one detect with melanoma is it sure that he/she gonna die after 5 or 10 year

Dr. Sanjay Singh Rai

Medical Oncology and Hematology

No if melanoma is localized it can be removed by surgery

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Axiommax Oncology Pvt Ltd
Address: A/303, Atrium -1, Andheri - Kurla Road, Mumbai – 400 059 India

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Provide right medicines

Prescriptions are complex documents. We proof read and recheck at various steps to provide you the right medication in the correct form and dose

In accordance with the law

Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945

Dabazine 100 Injection

General Information

Contains

Marketer

Storage

Product introduction

Uses of Dabazine Injection

Benefits of Dabazine Injection

Side effects of Dabazine Injection

How to use Dabazine Injection

How Dabazine Injection works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Frequently asked questions

How is Dabazine 100 Injection administered?

Is Dabazine 100 Injection a vesicant?

What is Dabazine 100 Injection used for?

How effective is Dabazine 100 Injection?

Does Dabazine 100 Injection cause hair loss?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

References

Patient concerns

Brain star tablet for which disice

if any one detect with melanoma is it sure that he/she gonna die after 5 or 10 year

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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