Darbotin 40 Injection

Written By Dr. Shreya Gupta, MDS (Oral Pathology & Microbiology), BDS

Reviewed By Dr. Shilpa Garcha, MD (Pharmacology), MBBS

Last updated on 12 Nov 2024 | 01:12 AM (IST)

Darbotin 40 Injection is used in the treatment of anemia that may have occurred due to chronic kidney disease or chemotherapy. It works by stimulating the bone marrow to produce more red blood cells.

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1/2

0.4 ml Injection

Genuine

Authenticity Assured

Prescription

required

Cold stored

Stored between 2-8°C

517 people

viewed recently

General Information

Contains

Darbepoetin alfa (40mcg)

Marketer

Wockhardt Ltd

Storage

Store in a refrigerator (2 - 8°C). Do not freeze.

The content is shown in English

Product introduction

Darbotin 40 Injection is a medicine that needs to be used with utmost care because it can lead to serious side effects. It is important that you seek treatment from a doctor who is experienced in providing this medical therapy. You should follow all the directions of the doctor strictly. It is given under the supervision of a healthcare professional.

Common side effects include abdominal pain, high blood pressure, rash, injection site pain, breathlessness, cough, and peripheral edema. Inform your doctor if there are symptoms of very high blood pressure such as severe headache, problems with your eyesight, nausea, vomiting, or fits (seizures).

Your doctor may get your blood tests done regularly to monitor the levels of salts (electrolytes such as potassium), hemoglobin, and blood cells in your blood. You should stop taking it and consult with a doctor if you develop shortness of breath or skin rash.

Before taking Darbotin 40 Injection, tell your doctor if you have heart disease, high blood pressure, or have had a seizure or stroke. If you are pregnant or breastfeeding, or plan to become pregnant or breastfeed, consult your doctor to make sure it is safe for you.

Uses of Darbotin Injection

Benefits of Darbotin Injection

Treatment of Anemia due to chronic kidney disease
Anemia is a condition where your body does not have enough red blood cells to carry oxygen around your body. Chronic kidney disease (CKD) refers to the loss of normal kidney function over a long span of time. CKD progresses gradually over a few years but may become permanent if left untreated. CKD can lead to anemia. Darbotin 40 Injection can boost your levels of red blood cells and reduce the symptoms of anemia such as tiredness and weakness. Taking this injection improves the quality of life.

Treatment of Anemia due to cancer chemotherapy
Low red blood cell count is termed as anemia. Cancer treatment with chemotherapy often causes many side effects, one of the major ones being anemia. Darbotin 40 Injection stimulates the production of red blood cells in bone marrow and regulates the haemoglobin in the blood. This treats anemia in cancer patients receiving chemotherapy.

Side effects of Darbotin Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Darbotin

Abdominal pain
High blood pressure
Rash
Injection site pain
Breathlessness
Cough
Peripheral edema
Procedural hypotension (low blood pressure)
Convulsion
Thromboembolism

How to use Darbotin Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Darbotin Injection works

Darbotin 40 Injection is an erythropoiesis-stimulating agent (ESA). It works by stimulating the bone marrow (soft tissue inside the bones which produces red blood cells) to produce more red blood cells.

All substitutes for Darbotin 40 Injection

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Darbotin 40 Injection helps in the treatment of anemia that may have occurred due to chronic kidney disease or cancer chemotherapy.
It is given as a single injection under your skin, additionally, it can be given intravenously.
Your doctor may get your blood tests done regularly to monitor the levels of hemoglobin, blood cells, in your blood.
Stop taking Darbotin 40 Injection and inform your doctor if you develop shortness of breath or skin rash.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Darbotin 40 Injection. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Darbotin 40 Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Darbotin 40 Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

SAFE

Darbotin 40 Injection does not usually affect your ability to drive.

Kidney

SAFE IF PRESCRIBED

Darbotin 40 Injection is safe to use in patients with kidney disease. No dose adjustment of Darbotin 40 Injection is recommended.

Liver

CAUTION

Darbotin 40 Injection should be used with caution in patients with liver disease. Dose adjustment of Darbotin 40 Injection may be needed. Please consult your doctor.

Frequently asked questions

How long does it take for Darbotin 40 Injection to start working?

You will be able to notice an increase in the count of red blood cells (hemoglobin levels) in 2-6 weeks of starting Darbotin 40 Injection. If you have any other concerns, consult your doctor.

Is Darbotin 40 Injection safe to use?

Darbotin 40 Injection is a medicine that needs to be used with utmost care because it can lead to serious side effects and even death of the patient. It is important that you seek treatment from a doctor who is experienced in providing Darbotin 40 Injection therapy. Follow all the directions strictly.

Other than PRCA, can there be other reasons for not responding to Darbotin 40 Injection?

You may not respond to Darbotin 40 Injection if you have deficiencies of iron, folic acid or vitamin B12. It is important that you take measures to correct these deficiencies. Other reasons behind not responding to the treatment could be bleeding, infections, inflammation and bone marrow fibrosis. Therefore, consult our doctor regarding the same.

Can Darbotin 40 Injection be used in children?

Yes, Darbotin 40 Injection is used to treat anemia due to chronic kidney disease in children who are above 1 year of age. The effectiveness of Darbotin 40 Injection and side effects seen in children are similar to adults. However, consult your doctor if you are not sure.

Can Darbotin 40 Injection affect blood pressure?

Yes, Darbotin 40 Injection can affect blood pressure. During initial therapy with Darbotin 40 Injection, blood pressure should be monitored and those who have high blood pressure should take appropriate measures to control blood pressure. Your doctor may stop Darbotin 40 Injection if the blood pressure remains uncontrolled.

Who should not take Darbotin 40 Injection?

Individuals who have cancer but have not been prescribed Darbotin 40 Injection by the doctor should not take it. Additionally, patients with uncontrolled hypertension (high blood pressure), patients with a history of anemia called pure red cell aplasia (PRCA) that starts after treatment with Darbotin 40 Injection or other erythropoietin medicines, and patients with a history of serious allergic reaction to this medicine should not take this medicine.

Fact Box

Chemical Class

Amino Acids, Peptides Analogues

Habit Forming

Therapeutic Class

BLOOD RELATED

Action Class

Erythropoiesis-stimulating agent (ESA)

Related lab tests

Complete Blood Count

Peripheral Smear Examination

References

Kaushansky K, Kipps TJ. Hematopoietic Agents: Growth Factors, Minerals, and Vitamins. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1071-72.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 358-59.
Darbepoetin alfa. Milton Road, Cambridge: Amgen Ltd.; 2001 [revised Sep. 2017]. [Accessed 23 Jan. 2019] (online) Available from:
Darbepoetin alfa. Thousand Oaks, CA: Amgen Inc.; 2001. [Accessed 07 Apr. 2019] (online) Available from:
CiplaMed. Darbepoetin Alfa [Product Information]. [Last Reviewed: June 2019]. [Accessed 17 Jun. 2023] (online) Available from:
Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006. Darbepoetin. [Accessed 17 Jun. 2023] (online) Available from:
Darbepoetin alfa [Prescribing Information]. Thousand Oaks, California: Amgen Inc.; 2019. [Accessed 17 Jun. 2023] (online) Available from:
Aranesp Injection (Darbepoetin alfa) [Product Information]. [Accessed 17 Jun. 2023] (online) Available from:

User feedback

Patients taking Darbotin 40 Injection

Once A Week

57%

Twice A Month

29%

Once A Month

Once A Day

Twice A Week

What are you using Darbotin Injection for?

Anemia due to chronic kidney disease

80%

Others

10%

Anemia due to cancer chemotherapy

10%

Patient concerns

Blood Hb is found 5.9 so wat is it

Dr. Ila Jain Khandelwal

Pathology

Dear PATIENT from 1mg. The hemoglobin is very low, which can be due to anemia. I suggest you should consult a Hematologist /Physician for this.

how to resolve the problem of anemia?

Dr. Rekha Pohani

Dietetics/Nutrition

Intake of dates and jaggery will help

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Wockhardt Ltd
Address: Wockhardt Towers, Bandra Kurla Complex, Bandra (East), Mumbai 400051, Maharashtra, India

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Darbotin 40 Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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Why we need a prescription?

Provide right medicines

Prescriptions are complex documents. We proof read and recheck at various steps to provide you the right medication in the correct form and dose

In accordance with the law

Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945

Darbotin 40 Injection

General Information

Contains

Marketer

Storage

Product introduction

Uses of Darbotin Injection

Benefits of Darbotin Injection

Side effects of Darbotin Injection

How to use Darbotin Injection

How Darbotin Injection works

All substitutes for Darbotin 40 Injection

Cresp 40 Injection

Darbelife 40mcg Pfs Injection

Kabidarba 40 Injection

Darcept 40 Injection

Darbosis 40 Injection

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Frequently asked questions

How long does it take for Darbotin 40 Injection to start working?

Is Darbotin 40 Injection safe to use?

Other than PRCA, can there be other reasons for not responding to Darbotin 40 Injection?

Can Darbotin 40 Injection be used in children?

Can Darbotin 40 Injection affect blood pressure?

Who should not take Darbotin 40 Injection?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Complete Blood Count

Peripheral Smear Examination

References

User feedback

Patients taking Darbotin 40 Injection

What are you using Darbotin Injection for?

Patient concerns

Blood Hb is found 5.9 so wat is it

how to resolve the problem of anemia?

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

In case of any issues, contact us

Lab tests offered by us

Related/Popular tests