Decitas Injection
Written By Dr. Radhika Dua, MDS, BDS
Reviewed By Dr. Shilpa Garcha, MD (Pharmacology), MBBS
Last updated on 08 Nov 2024 | 01:09 AM (IST)
Decitas Injection is used in the treatment of blood cancer called acute myeloid leukaemia (AML). It is also used to treat patients with myelodysplastic syndrome (MDS). It may be used to treat other conditions, as determined by the doctor.
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General Information
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Product introduction
Decitas Injection is also used with certain other medicines as part of combination chemotherapy. It is given as an injection into the vein under the supervision of a doctor. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
The most common side effects of this medicine include nausea, vomiting, diarrhea, headache, fever and lung infection. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with heart, liver, and blood uric acid levels.
Before taking it, tell your doctor if have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. Use of effective contraception by both males and females during treatment is important to avoid pregnancy.
The most common side effects of this medicine include nausea, vomiting, diarrhea, headache, fever and lung infection. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with heart, liver, and blood uric acid levels.
Before taking it, tell your doctor if have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. Use of effective contraception by both males and females during treatment is important to avoid pregnancy.
Uses of Decitas Injection
Benefits of Decitas Injection
Myelodysplastic syndrome
Decitas Injection is used to treat myelodysplastic syndrome, a group of conditions in which the bone marrow produces blood cells that are abnormal in structure and function, and does not produce enough healthy blood cells. Decitas Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is an effective, yet very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.
Decitas Injection is used to treat myelodysplastic syndrome, a group of conditions in which the bone marrow produces blood cells that are abnormal in structure and function, and does not produce enough healthy blood cells. Decitas Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is an effective, yet very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.
Blood cancer
Blood cancer, also called leukemia, is a cancer of the blood-forming tissues, that decreases the body's ability to fight infection. Decitas Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is an effective medicine but you should discuss the side effects and benefits of this medicine with your doctor. Let your doctor know if any of the side effects bothers you.
Blood cancer, also called leukemia, is a cancer of the blood-forming tissues, that decreases the body's ability to fight infection. Decitas Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is an effective medicine but you should discuss the side effects and benefits of this medicine with your doctor. Let your doctor know if any of the side effects bothers you.
Side effects of Decitas Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Decitas
- Nausea
- Vomiting
- Headache
- Fever
- Lung infection
- Decreased white blood cell count (neutrophils)
- Nosebleeds
- Anemia (low number of red blood cells)
- Low blood platelets
- Diarrhea
- Pneumonia
How to use Decitas Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Decitas Injection works
Decitas Injection interferes with the growth of DNA and RNA of the cancer cells by substituting their building blocks. It prevents the cancer cells from growing and multiplying.
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For information purposes only. Consult a doctor before taking any medicine.
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Quick tips
- Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine.
- Inform your doctor immediately if you notice any signs of infection such as fever, sore throat, rash or severe diarrhea.
Safety advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Decitas Injection. Please consult your doctor.

Pregnancy
CONSULT YOUR DOCTOR
Decitas Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding
UNSAFE
Decitas Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving
UNSAFE
Decitas Injection may cause side effects which could affect your ability to drive.
You may feel tired or weak after using Decitas Injection this could affect your ability to drive.
You may feel tired or weak after using Decitas Injection this could affect your ability to drive.

Kidney
CAUTION
Decitas Injection should be used with caution in patients with kidney disease. Dose adjustment of Decitas Injection may be needed. Please consult your doctor.

Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Decitas Injection in patients with liver disease. Please consult your doctor.

Frequently asked questions
Decitas Injection is not a vesicant and is not known to cause severe local tissue damage upon extravasation (leaking of injected Decitas Injection into the surrounding tissues from the site of administration) when injected.
The effectiveness of Decitas Injection depends upon several factors including the patient's clinical condition, number of treatment cycles etc. and may vary depending upon the individual response.
Yes. Hair loss (alopecia) is among the known side effects of Decitas Injection.
Decitas Injection comes as a powder to be to be added to fluid and injected slowly over 3 hours into a vein (slow i.v infusion) by a doctor who is experienced in giving chemotherapy medications for cancer in a hospital or a clinic.
Fact Box
Chemical Class
Azacitidine Derivative
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Antimetabolites
Related lab tests
References
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 364.
- Decitabine. High Wycombe, Bucks: Janssen-Cilag Ltd.; 2012 [revised 07 Feb. 2019]. [Accessed 26 Mar. 2019] (online) Available from:
- Decitabine. Netherlands: Pharmachemie B.V.; 2006 [revised date]. [Accessed 26 Mar. 2019] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:

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Patient concerns
Can blood cancer patients 1st stage do sex with normal girl Sir a blood cancer patients do sex with normal girl can any problem or cause doing with girl or side effect give suggestions Thanks
Dr. Vijay Sharnangat
Medical Oncology and Hematology
Wait till blood cancer gets cured.
Blood Cancer. Is there any medicine to cure blood cancer.
Dr. Aanchal Maheshwari
Ayurveda
Case has to be seen in person
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
Marketer details
Name: Intas Pharmaceuticals Ltd
Address: Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Address: Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Vendor Details
Country of origin: India
A licensed vendor partner from your nearest location will deliver Decitas Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
A licensed vendor partner from your nearest location will deliver Decitas Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
In case of any issues, contact us
Email ID: [email protected]Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
Lab tests offered by us
- CBC (Complete Blood Count)
- FBS (Fasting Blood Sugar)
- Thyroid Profile Total (T3, T4 & TSH)
- HbA1c (Glycosylated Hemoglobin)
- Glucose - Postprandial
- Lipid Profile
- Vitamin D (25-Hydroxy)
- Urine R/M (Urine Routine & Microscopy)
- Coronavirus Covid-19 Test (RT-PCR technique)
- LFT (Liver Function Test)
- Kidney Function Test
- TSH (Thyroid Stimulating Hormone) Ultrasensitive
- ESR (Erythrocyte Sedimentation Rate)
- Uric Acid
- Vitamin B12
- C- Reactive Protein Quantitative
- Urine Culture and Sensitivity
- Serum Electrolyte
- Serum Calcium
- Creatinine
- Diabetes Screening
- KFT with Electrolytes (Kidney Function Test with Electrolytes)
- Cholesterol - Total
- Hemoglobin
- Complete Haemogram
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