Deferglob 500mg Tablet

Written By Dr. Shreya Gupta, MDS (Oral Pathology & Microbiology), BDS

Reviewed By Dr. Lalit Kanodia, MBA, MD Pharmacology

Last updated on 11 Nov 2024 | 01:07 AM (IST)

Deferglob 500mg Tablet is a medicine used in the treatment of chronic iron overload caused by frequent blood transfusion. It helps remove the excess iron from the body and reduce the risk of it causing organ damage.

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1/2

10 tablets

General Information

Contains

Deferasirox (500mg)

Marketer

Globela Pharma Pvt Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Deferglob 500mg Tablet should be taken on an empty stomach. Take it in the exact dose and duration and take it regularly at a fixed time each day to get the maximum benefit from it.

Using of Deferglob 500mg Tablet may cause common side effects such as nausea, headache, constipation, and diarrhea. If the side effects persist or worsen, inform your doctor.

Before using this medicine, let your doctor know if you have any kidney or liver diseases. Let your doctor also know about all the other medicines you are taking to ensure your safety.

Uses of Deferglob Tablet

Treatment of Iron overload

Benefits of Deferglob Tablet

Treatment of Iron overload
Iron overload, as the name suggests, means excess of iron in the human body. Too much iron can cause organ damage, which can lead to conditions such as cancer, irregular heartbeat and cirrhosis of the liver. Symptoms are related to conditions that arise from iron overload such as high blood sugar levels (diabetes), darkening of the skin, abnormal heart rhythm or arthritis. By using Deferglob 500mg Tablet, this excess of iron can be decreased to safe levels by removing it from the body through stools. This helps to reduce the risk of organ damage and prevents further complications. Take Deferglob 500mg Tablet as prescribed by the doctor to get the maximum benefit.

Side effects of Deferglob Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Deferglob

Nausea
Headache
Vomiting
Rash
Abdominal pain
Constipation
Itching
Abdominal distension
Diarrhea

How to use Deferglob Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Deferglob 500mg Tablet is to be taken empty stomach.

How Deferglob Tablet works

Deferglob 500mg Tablet traps and removes excess iron which is then excreted mainly in the stools. This reduces the risk of organ damage.

Quick tips

Deferglob 500mg Tablet is used to reduce excess iron from the body.
Inform your doctor if you also have upper stomach pain, clay-colored stools, or jaundice (yellowing of your skin or the whites of your eyes).
Take an adequate amount of water while taking Deferglob 500mg Tablet.
Deferglob 500mg Tablet may cause dizziness. It is advisable not to drive or operate any machinery until you feel normal again.
If you are taking any antacid, take them 2 hours before or after Deferglob 500mg Tablet.
Inform your doctor if you have any liver or kidney disease.
Inform your doctor if you are pregnant or breastfeeding.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Deferglob 500mg Tablet. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Deferglob 500mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding

SAFE IF PRESCRIBED

Deferglob 500mg Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Driving

UNSAFE

Deferglob 500mg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

UNSAFE

Deferglob 500mg Tablet is probably unsafe to use in patients with kidney disease and should be avoided. Please consult your doctor.

Liver

CAUTION

Deferglob 500mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Deferglob 500mg Tablet may be needed. Please consult your doctor.

Frequently asked questions

What is Deferglob 500mg Tablet used for?

Deferglob 500mg Tablet is used for removing excess iron from the body due to repeated blood transfusions in patients with beta thalassemia major (a blood disorder)

How does Deferglob 500mg Tablet work?

Deferglob 500mg Tablet works by binding to excess iron in the blood and removing it from the body through stool.

Fact Box

Chemical Class

Triazole & benzoate derivative

Habit Forming

Therapeutic Class

BLOOD RELATED

Action Class

Iron chelating agents

Related lab tests

Iron Serum

Iron Studies

Total Iron Binding Capacity

References

Byrns MC, Penning TM. Environmental Toxicology: Carcinogens and Heavy Metals. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1875-76.
Kosnett MJ. Heavy Metal Intoxication & Chelators. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 1010.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 365.
Deferasirox. Camberley, Surrey: Novartis Pharmaceuticals UK Ltd.; 2006 [revised 23 Jul. 2018]. [Accessed 6 Apr. 2019] (online) Available from:
Medscaape. Deferasirox. [Accessed 6 Apr. 2019] (online) Available from:
Deferasirox. Camberley, Surrey: Novartis Pharmaceuticals UK Ltd.; 2006 [revised 23 Jul. 2018]. [Accessed 25 Jan. 2019] (online) Available from:
Drugs.com. Deferasirox Pregnancy and Breastfeeding Warnings. [Accessed 6 Apr. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 6 Apr. 2019] (online) Available from:

Patient concerns

Hello doctor I have thallassemia major since birth and due to iron overload of repetitive blood transfusion i have diagnosed with diabetes 3 yr ago -at the time of diabetes diagnosis my sugar level is 650 mg/dl. Now according to my case what could be the state of my diabetes type 1 or type 2 ?

Dr. Amit Modi

Paediatrics

Hello, Diabetes in thalassaemia is thought to be caused mainly by iron overload, from repeated blood transfusions, damaging the pancreas. Insulin secretion may be reduced, possibly because iron is directly toxic to the insulin producing pancreatic ?-cells. So it is type 1 DM .

Hello doctor i have thallasemia major since birth and due to iron overload of repetitive blood transfusions from this disease i was diagnosed with diabetes 2 yrs. ago Now my query is can i control my sugar by controlling iron/ferritin?

Dr. Ashwin Porwal

Internal Medicine

No you have to take insulin or Oral hypoglycemic agents for it

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Marketer details

Name: Globela Pharma Pvt Ltd
Address: 357, G.I.D.C. Road No.3,Sachin, Surat - 394 230 ,Gujarat, India

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Deferglob 500mg Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945