Defwell Syrup

Reviewed By Dr. Varun Gupta, MD Pharmacology, MBBS

Last updated on 28 Oct 2024 | 01:07 AM (IST)

Defwell Syrup belongs to a group of medicines known as corticosteroids. Its anti-inflammatory and immunosuppressive properties give it the ability to treat a wide range of conditions in children. It is also one of the primary medicines used for Duchenne muscular dystrophy in infants and children.

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1/2

30 ml Syrup

General Information

Contains

Deflazacort (6mg/5ml)

Marketer

Treatwell Pharma

Storage

Store below 30°C

The content is shown in English

Your child’s medicine at a glance

Give Defwell Syrup to your child orally, either before or after food. Giving it with food helps prevent the risk of developing a stomach upset. Always give the dose as prescribed by the doctor since that depends on the severity and type of infection, body weight, and age of your child. If your child gains or loses weight during treatment, make sure to let the doctor know. Never alter the dose by yourself as that may increase the risk of serious implications in your child. If your child vomits within 30 minutes of taking this medicine, help the child calm down and repeat the same dose, but skip it if it is already time for the next dose.

It is important to complete the full course of this medicine as stopping it abruptly may cause serious side effects. To stop this medicine, the doctor will gradually taper down the dose of this medicine to avoid withdrawal symptoms. Defwell Syrup can suppress your child’s immune system, making your child more prone to infections. Your child may need frequent medical checkups and tests. Therefore, it is important to follow up with your child’s doctor frequently during the treatment. The doctor may also advise vision and bone mineral density check for your child as Defwell Syrup can impact both of these.

This medicine may cause side effects like weight gain, increased appetite, upper respiratory tract infection, cough, abnormal hair growth, central obesity, and fluid and electrolyte disturbance. Reach out to your child’s doctor if these side effects appear.

Let your child’s doctor know if your child is already taking medicines for any type of infection. Also, narrate your child’s complete medical history, including heart, blood, skin, bone, and hormonal disorders or any prior episodes of allergy, eye disease, birth defects, lung anomaly, liver impairment, and kidney malfunction. This information is critical for dose alterations and in planning your child’s overall treatment.

Uses of Defwell Syrup in children

Treatment of Cancer
Treatment of Inflammatory conditions
Treatment of Autoimmune conditions
Treatment of Duchenne muscular dystrophy(DMD)

Benefits of Defwell Syrup for your child

Treatment of Cancer
Defwell Syrup helps in the treatment of a variety of cancers, such as leukemia, lymphoma, and multiple myeloma. It works by suppressing the immune system thereby reducing inflammation around the site of cancer. It is used specifically to decrease swelling (edema), associated with tumors of the spine and brain. Moreover, it helps to treat or prevent allergic reactions in cancer patients.

Treatment of Inflammatory conditions
Defwell Syrup gives relief in inflammatory conditions that affect muscles and joints such as arthritis and ankylosing spondylitis. It also helps manage other inflammatory conditions such as asthma, inflammatory bowel disease, uveitis, ulcerative colitis, and allergies. It works by blocking certain chemicals that cause pain and swelling.

Treatment of Autoimmune conditions
Defwell Syrup gives relief in autoimmune conditions like psoriasis, rheumatoid arthritis, eczema, atopic dermatitis, etc. It works by lowering your immune system’s response to these conditions thereby reducing symptoms such as swelling, pain, itching, and other allergic-type reactions.

Treatment of Duchenne muscular dystrophy(DMD)
Duchenne muscular dystrophy (DMD) is a type of muscular dystrophy, characterized by muscle weakness and atrophy due to the effect of the body’s immune system mechanisms. Defwell Syrup slows the progression of DMD. The exact mechanism by which it acts is unclear, but it is thought to help mediate the condition by suppressing the immune system. For DMD, Defwell Syrup is approved to be used in children above 5 years of age.

Side effects of Defwell Syrup in children

Defwell Syrup does not pose serious side effects and is well-tolerated by children. In case the side effects do occur, they’re likely to subside once the body adapts to the medicine. Consult your child’s doctor if these side effects persist or bother your child. The most common side effects include-

Common side effects of Defwell

Nasopharyngitis (inflammation of the throat and nasal passages)
Increased appetite
Weight gain
Frequent urge to urinate
Cushing syndrome
Cough
Abnormal hair growth
Upper respiratory tract infection
Obesity

How can I give Defwell Syrup to my child?

Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. Defwell Syrup may be taken with or without food, but it is better to take it at a fixed time.
Avoid Defwell Syrup with salad and vegetable diet.

How Defwell Syrup works

Defwell Syrup is a corticosteroid medicine. It acts like the body’s natural anti-inflammatory hormones called glucocorticoids. Defwell Syrup decreases the formation of chemical substances like prostaglandins, leukotrienes, and interleukins that are involved in inflammation, allergy, and cell multiplication. It also suppresses the immune system and stops the immune mechanisms from causing any self-damage to the body.

All substitutes for Defwell Syrup

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Prefer giving Defwell Syrup with food as an empty stomach can trigger acidity and gastric reflux.
Avoid giving antacids along with Defwell Syrup. If both need to be given, leave a gap of at least 2 hours between administration of Defwell Syrup and antacids.
Do not give it more often or for longer than advised by your doctor.
Defwell Syrup can make it harder for your child to fight off infections. Notify your doctor if you notice any signs of infection such as a fever or sore throat.
Do not stop the medicine abruptly. Seek the doctor’s guidance to taper the dose gradually as sudden withdrawal may result in a steroid withdrawal syndrome.

Safety advice

Kidney

SAFE IF PRESCRIBED

Defwell Syrup is safe to use in patients with kidney disease. No dose adjustment of Defwell Syrup is recommended.
Dose alterations may be required in severe kidney disease. Discuss with your child’s doctor thoroughly before giving Defwell Syrup to your child.

Liver

CAUTION

Defwell Syrup should be used with caution in patients with liver disease. Dose adjustment of Defwell Syrup may be needed. Please consult your doctor.

Frequently asked questions

Is Defwell Syrup a steroid?

Yes, Defwell Syrup is a steroid medicine also known as glucocorticoids which occur naturally in the body. These glucocorticoids help to maintain health and wellbeing. Defwell Syrup increases the corticosteroids levels in the body which helps in treating various illnesses involving inflammation (redness, tenderness, heat and swelling).

In what conditions should I avoid giving Defwell Syrup to my child?

Avoid giving Defwell Syrup to your child if they have conditions like cardiac disease or congestive heart failure (except in the presence of active rheumatic carditis), hypertension, thromboembolic disorders, or diabetes mellitus. Defwell Syrup should also be avoided if your child has a family history of active TB, active herpes infection, osteoporosis, myasthenia gravis, or renal insufficiency.

What do I need to know about Defwell Syrup and my child’s immunizations?

For certain vaccines (live or live-attenuated vaccines), your child will need to wait 4 to 6 weeks before starting Defwell Syrup. Hence, your child needs to receive all immunizations according to immunization guidelines before they start taking Defwell Syrup.

How can I store Defwell Syrup at home?

Keep the medicine in a cool dry place out of the reach of children and pets. This will help avoid any accidental intake.

My child is suffering from a seizure disorder. Is it safe to give Defwell Syrup to my child?

Ans: Prolonged intake of Defwell Syrup can lead to mental illness as well as a seizure disorder. Therefore, any child who is already suffering from seizure disorder should not take Defwell Syrup.

Fact Box

Chemical Class

Gluco/mineralocorticoids, progestogins and derivatives

Habit Forming

Therapeutic Class

HORMONES

Action Class

Glucocorticoids

References

Patient concerns

Duchenne Muscular Dystrophy & Developmental delay , speech delay

Dr. Gopal Samdani

Paediatrics

Your Question is not clear to me . Please ask your question more clearly and in detail and also try be more specific and descriptive.

Babu ke muscular dystrophy genetic problam 48&50gens delite dmd Muscular dystrophy genetic problam medcian pls

Dr. Vipul Aggarwal

Orthopaedics

There are no medcines for It as far as my knowledge is concernedAnd these case are seen by PediatricianPlease let me know if there is any itber way i can help u

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Treatwell Pharma
Address: 802, Safal Prelude, Nr. Ashwaraj Bunglow, Nr. Prahlad nagar Garden, Off – S.G. Highway, Ahmedabad-380015, Gujarat, INDIA.

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Defwell Syrup. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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