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Deninta SC Injection

Denosumab (60mg)
Genuine
Authenticity Assured
Prescription
required
Cold stored
Stored between 2-8°C
Deninta SC Injection is a medicine used in the treatment of osteoporosis in postmenopausal women and in men at increased risk of fractures. It makes the bones strong and reduce the risk of fractures.

Written By Dr. Anuj Saini, MMST, MBBS,
Reviewed By Dr. Varun Gupta, MD Pharmacology, MBBS,
Last updated on 12 Nov 2024 | 01:00 AM (IST)
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1 ml Injection
Gurgaon
Payment

Payment

Online only

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Expiry after

Expiry after

Sep, 2026

 
 
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General Information

Contains

Denosumab (60mg)

Marketer

Intas Pharmaceuticals Ltd

Storage

Store in a refrigerator (2 - 8°C). Do not freeze.
The content is shown in English
Deninta SC Injection image
Deninta SC Injection image

Product introduction

Deninta SC Injection is given by a healthcare professional and should not be self-administered. You should use it regularly and at the same time each day to get maximum benefit from it. Continue using it as recommended by your doctor and complete the dose even if you feel better. To make it more effective, take adequate amount of calcium and vitamin D supplements while on treatment with this medicine.

Some common side effects of this medicine include headache, pain in extremity, musculoskeletal pain, nerve pain, constipation, and rash. Talk to your doctor if any of these side effects does not go away with time or get worse. Your doctor may help with ways to reduce or prevent these symptoms.

To make sure the medicine is safe for you, before taking it, let your doctor know of all the other medicines you are taking. It is important for pregnant and breastfeeding mothers to ask the advice of their doctors before using this medicine.

Uses of Deninta Injection

Side effects of Deninta Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Deninta
  • Rash
  • Musculoskeletal (bone, muscle or joint) pain
  • Nerve pain
  • Eczema
  • Upper respiratory tract infection
  • Sciatica
  • Pain in extremities
  • Headache
  • Back pain
  • Joint pain
  • Urinary tract infection
  • Constipation
  • Abdominal discomfort
  • Hair loss
  • Hypercholesterolemia (high cholesterol)
  • Cystitis

How to use Deninta Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Deninta Injection works

Deninta SC Injection is a monoclonal antibody. It binds to a protein that causes bone loss, thereby strengthening the bone and minimizing the risk of fractures.

All substitutes for Deninta SC Injection

For information purposes only. Consult a doctor before taking any medicine.

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Denoci 60 Injection

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Quick tips

  • Deninta SC Injection is a medication used to treat thinning of the bones (called osteoporosis).
  • Take calcium and vitamin D to help build your bones when taking Deninta SC Injection.
  • Do not take if you are pregnant or plan to become pregnant.
  • May cause a rare problem of the jaw (osteonecrosis), mostly seen after a dental procedure. Tell your doctor if you develop sudden jaw pain.
  • Deninta SC Injection may also increase the risk of infection. Avoid being close to people with cold, flu or other contagious illnesses.
  • Tell your doctor if you develop a rash while taking Deninta SC Injection.
  • Deninta SC Injection is a medication used to treat thinning of the bones (called osteoporosis).
  • Take calcium and vitamin D to help build your bones when taking Deninta SC Injection.
  • Do not take if you are pregnant or plan to become pregnant.
  • May cause a rare problem of the jaw (osteonecrosis), mostly seen after a dental procedure. Tell your doctor if you develop sudden jaw pain.
  • Deninta SC Injection may also increase the risk of infection. Avoid being close to people with cold, flu or other contagious illnesses.
  • Tell your doctor if you develop a rash while taking Deninta SC Injection.

Safety advice

Alcohol

Alcohol

CAUTION
Caution is advised when consuming alcohol with Deninta SC Injection. Please consult your doctor.
Pregnancy

Pregnancy

UNSAFE
Deninta SC Injection is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Deninta SC Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving

Driving

SAFE
Deninta SC Injection does not usually affect your ability to drive.
Kidney

Kidney

CAUTION
Deninta SC Injection should be used with caution in patients with severe kidney disease. Dose adjustment of Deninta SC Injection may be needed. Please consult your doctor.
Liver

Liver

CAUTION
Deninta SC Injection should be used with caution in patients with severe liver disease. Dose adjustment of Deninta SC Injection may be needed. Please consult your doctor.

Frequently asked questions

There is no optimal duration of treatment of osteoporosis with Deninta SC Injection. The patient’s response and tolerability to the medicine is continuously monitored through periodic assessments, especially after 5 years of use of Deninta SC Injection. Depending on this, the duration of taking Deninta SC Injection is decided.
Yes, hair loss is a common side effect of Deninta SC Injection though it does not affect everyone. Discuss with your doctor if you have concerns regarding your hair loss.
Deninta SC Injection is not a chemotherapy drug. It is a protein (monoclonal antibody) that interferes with the action of another protein in order to treat bone loss and osteoporosis. Treatment with Deninta SC Injection makes the bones stronger and less likely to break.
Deninta SC Injection is available as an injection and is given by a healthcare professional. It is given once in 6 months. Your doctor may also advise you to take calcium and vitamin D while taking Deninta SC Injection.
No, pregnant women should not take Deninta SC Injection. You must use an effective method of birth control during and for at least 5 months after the last dose of Deninta SC Injection if you can become pregnant.
Deninta SC Injection should be stored in a refrigerator at 36°F to 46°F (2°C to 8°C) in the original carton. Warm temperatures can make it ineffective, and therefore proper storage is necessary. When you remove it from the refrigerator, keep it at room temperature [up to 77°F (25°C)] in the original carton and use it within 14 days.
Osteonecrosis is a rare side effect of Deninta SC Injection. It refers to the damage caused to the bone of jaw. To avoid this, you should maintain good oral hygiene and receive routine dental check ups while taking Deninta SC Injection. Contact your doctor and dentist immediately if you experience any problems with your mouth or teeth such as loose teeth, discharge, pain or swelling, or non-healing of sores. These could be signs of osteonecrosis of jaw.
There is no optimal duration of treatment of osteoporosis with Deninta SC Injection. The patient’s response and tolerability to the medicine is continuously monitored through periodic assessments, especially after 5 years of use of Deninta SC Injection. Depending on this, the duration of taking Deninta SC Injection is decided.
Yes, hair loss is a common side effect of Deninta SC Injection though it does not affect everyone. Discuss with your doctor if you have concerns regarding your hair loss.
Deninta SC Injection is not a chemotherapy drug. It is a protein (monoclonal antibody) that interferes with the action of another protein in order to treat bone loss and osteoporosis. Treatment with Deninta SC Injection makes the bones stronger and less likely to break.
Deninta SC Injection is available as an injection and is given by a healthcare professional. It is given once in 6 months. Your doctor may also advise you to take calcium and vitamin D while taking Deninta SC Injection.
No, pregnant women should not take Deninta SC Injection. You must use an effective method of birth control during and for at least 5 months after the last dose of Deninta SC Injection if you can become pregnant.
Deninta SC Injection should be stored in a refrigerator at 36°F to 46°F (2°C to 8°C) in the original carton. Warm temperatures can make it ineffective, and therefore proper storage is necessary. When you remove it from the refrigerator, keep it at room temperature [up to 77°F (25°C)] in the original carton and use it within 14 days.
Osteonecrosis is a rare side effect of Deninta SC Injection. It refers to the damage caused to the bone of jaw. To avoid this, you should maintain good oral hygiene and receive routine dental check ups while taking Deninta SC Injection. Contact your doctor and dentist immediately if you experience any problems with your mouth or teeth such as loose teeth, discharge, pain or swelling, or non-healing of sores. These could be signs of osteonecrosis of jaw.

Fact Box

Chemical Class

Monoclonal antibody (mAb)

Habit Forming

No

Therapeutic Class

PAIN ANALGESICS

Action Class

Bone resorption inhibitors- Monoclonal antibodies

Related lab tests

Calcium

References

  1. Bikle DD. Agents That Affects Bone Mineral Homoestasis. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 766.
  2. Friedman PA. Agents Affecting Mineral Ion Homeostasis and Bone Turnover. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1299.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 370.
  4. Drugs.com. Denosumab. [Accessed 02 Apr. 2019] (online) Available from:
  5. Denosumab. Milton Road, Cambridge: Amgen Ltd.; 2010 [revised Jun. 2018]. [Accessed 02 Apr. 2019] (online) Available from:
  6. Denosumab [Prescribing Information]. Thousand Oaks, California: Amgen Manufacturing Limited; 2013. [Accessed 20 Feb. 2024] (online) Available from:
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Intas Pharmaceuticals Ltd
Address: Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Deninta SC Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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