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Depin 5 Capsule

Written By Dr. Betina Chandolia, MDS, BDS
Reviewed By Dr. Varun Gupta, MD Pharmacology, MBBS
Last updated on 12 Nov 2024 | 01:09 AM (IST)
Depin 5 Capsule is a medicine used to treat high blood pressure (hypertension) and to prevent angina (heart-related chest pain). It belongs to a class of medicines known as calcium channel blockers. It lowers blood pressure and reduces the workload of the heart. This helps prevent heart attacks and strokes.
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General Information

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Depin 5 Capsule image
Depin 5 Capsule image
Depin 5 Capsule image
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Depin 5 Capsule image
Depin 5 Capsule image

Product introduction

Depin 5 Capsule may be prescribed alone or along with other medicines. The dose and how often you need it will be decided by your doctor so that you get the right amount to treat your condition. Your doctor may adjust the dose depending on how you respond to this medicine and your blood pressure levels. You can take it at any time of the day, with or without food, but it is best to take it at the same time each day. Take this medicine as soon as you have taken it out of the packet. It is sensitive to light and may not work properly if it is left out of the pack for too long.

Keep taking it for as long as advised by your doctor. Even if you feel well, do not stop this medicine on your own because high blood pressure often has no symptoms. If you stop taking it, your condition may get worse. Keeping active with regular exercise, reducing your weight, and eating a healthy diet will also help control your blood pressure. Follow your doctor’s advice while taking this medicine.

The most common side effects include fatigue, edema (swelling), dizziness, unusual heartbeat (palpitations), flushing, constipation, and headache. Consult your doctor if any of these bother you, or do not go away.

Before taking it, let your doctor know if you have any heart, liver, or kidney problems. Pregnant or breastfeeding women should also consult their doctor for advice before taking this medicine. You also need to tell your doctor what other medicines you are taking, especially those used to treat high blood pressure or heart conditions. Avoid excessive alcohol intake while taking this medicine as it can significantly decrease your blood pressure and make you feel dizzy or light-headed. You should have your blood pressure checked regularly to make sure that this medicine is working properly.

Benefits of Depin Capsule

Prevention of Heart attack
Depin 5 Capsule helps lower your blood pressure and make it easier for your heart to pump blood around your body. This reduces the chances of you having a heart attack. It can also reduce the risk of dying if it is given immediately after a heart attack. This medicine needs to be taken regularly to be effective, so keep taking it even if you feel well. Do not stop without talking to your doctor.
Treatment of Hypertension (high blood pressure)
Depin 5 Capsule works by relaxing the blood vessels so that blood can flow more easily around your body. This lowers your blood pressure and reduces your risk of having a stroke, a heart attack, or kidney problems in the future. You do not usually feel any direct benefit from taking this medicine, but it works in the long term to keep you well. Take regularly, as prescribed for this medicine to be most effective, even if you feel better.
Prevention of Stroke
Depin 5 Capsule reduces the risk of future strokes. It helps lower your blood pressure and makes it easier for your heart to pump blood around your body. This reduces the chances of you having a stroke. Take it as advised by the doctor to get the maximum benefit.

Side effects of Depin Capsule

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Depin
  • Dizziness
  • Fatigue
  • Flushing (sense of warmth in the face, ears, neck and trunk)
  • Headache
  • Peripheral edema

How to use Depin Capsule

Take this medicine in the dose and duration as advised by your doctor. Depin 5 Capsule may be taken with or without food, but it is better to take it at a fixed time.

How Depin Capsule works

Depin 5 Capsule is a calcium channel blocker. In high blood pressure, it normalizes the blood pressure by relaxing the blood vessels to reduce the pressure on them, thereby improving the blood flow in the body. The enhanced blood flow in the body further relaxes the heart muscles by reducing the workload on the heart. It also improves the oxygen flow to the heart, thereby, preventing any heart-related chest pain.

Quick tips

  • Take it at the same time every day to help you remember to take it.
  • A sudden drop in your blood pressure may occur, especially when you first start taking Depin 5 Capsule. To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
  • It can cause ankle or foot swelling. To reduce the swelling, raise your legs while you are sitting down. Talk to your doctor if it does not go away.
  • It may cause dizziness. Do not drive or perform any activity that requires mental focus until you know how Depin 5 Capsule affects you.
  • Inform your doctor if you are pregnant, planning a pregnancy, or breastfeeding.

Safety advice

Alcohol

Alcohol

CAUTION
Caution is advised when consuming alcohol with Depin 5 Capsule. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Depin 5 Capsule may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding

Breast feeding

SAFE IF PRESCRIBED
Depin 5 Capsule is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving

Driving

CAUTION
Depin 5 Capsule may cause dizziness or weakness due to low blood pressure. Do not drive if these symptoms occur.
Depin 5 Capsule may make you feel dizzy, faint, extremely tired or have visual disturbances. This may affect your ability to drive.
Kidney

Kidney

SAFE IF PRESCRIBED
Depin 5 Capsule is safe to use in patients with kidney disease. No dose adjustment of Depin 5 Capsule is recommended.
However, talk to your doctor if you have any underlying kidney disease.
Liver

Liver

CAUTION
Depin 5 Capsule should be used with caution in patients with liver disease. Dose adjustment of Depin 5 Capsule may be needed. Please consult your doctor.
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Frequently asked questions

No, Depin 5 Capsule is not a diuretic medication. However, some evidence indicates that Depin 5 Capsule has a partial diuretic property which may result in increased sodium loss through urine. It is a medication which relaxes the blood vessels by directly acting on them. This helps to decrease the blood pressure of the individual. As a result, blood flows more easily and lowers blood pressure, which helps to reduce the strain or pressure on your heart.
No, Depin 5 Capsule is not bad for kidneys. In few research studies, taking Depin 5 Capsule in recommended doses has in fact been shown to be beneficial for the kidneys. It is not advised to use this medicine without consulting the doctor. It should be used exactly as prescribed.
Yes,Depin 5 Capsule can cause liver damage in some cases, but this is very rare. However, some people may develop a rise in liver enzymes after taking Depin 5 Capsule. Let your doctor know if you notice any such changes in your recent lab tests. Do not start this medication without consulting your doctor and do inform him if you have any history of liver disease or liver damage. This is because, in case of liver damage, dose adjustment may be required.
No, Depin 5 Capsule does not cause any change in blood sugar levels. It has been observed that Depin 5 Capsule has no effect on the release of insulin or change in blood sugar levels. However, before starting the medicine, inform the doctor if you are diabetic. This is done because the medicine for blood pressure is suggested accordingly when a patient is diabetic.
It is advised that you should consult your doctor before taking this medicine if you are pregnant, planning to become pregnant or breastfeeding. It should be used only if prescribed by the doctor in case of pregnancy. Studies have shown significant risks to the developing baby and it is given only if the benefits are clearly more than the risks involved.
Yes. Depin 5 Capsule can cause palpitations as a side effect. However, this is usually not bothersome and resolves as you continue with the treatment. If the symptom persists for long, consult the doctor who will suggest the ways to prevent it.
Yes, making small changes to your diet can help your medicine work better. You must take a low sodium and low-fat diet, and adhere to the lifestyle changes as advised by your doctor. You should also avoid eating grapefruit (chakotra) or drinking grapefruit juice while taking Depin 5 Capsule.
No, do not stop taking it on your own as it may worsen your condition. You should take Depin 5 Capsule in the dose and duration advised by your doctor. Consult your doctor for any query or dose modification.

Fact Box

Chemical Class

Dihydropyridinecarboxylic derivatives

Habit Forming

No

Therapeutic Class

CARDIAC

Action Class

Calcium Channel Blockers- Dihydropyridines (DHP)

References

  1. Michel T, Hoffman BB. Treatment of Myocardial Ischemia and Hypertension. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 757-58.
  2. Opie LH. Calcium Channel Blockers. In: Opie LH, Gersh BJ, editors. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. pp. 84-86.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 978-79.
  4. Nifedipine. New York, New York: Pfizer Labs; 2013. [Accessed 19 Mar. 2019] (online) Available from:
  5. Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 19 Mar. 2019] (online) Available from:
  6. National Health Sciences. Nifedipine. [Last Reviewed: 18 Feb. 2022]. [Accessed 25 Jul. 2023] (online) Available from:
  7. Khan KM, Patel JB, Schaefer TJ. Nifedipine. [Updated 2023 May 23]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023. [Accessed 25 Jul. 2023] (online) Available from:
  8. Central Drugs Standard Control Organisation. Nifedipine. [Accessed 25 Jul. 2023] (online) Available from:
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User feedback

Once A Day
70%
Twice A Day
19%
Thrice A Day
10%
Twice A Week
1%
High blood pressure
71%
Hypertensive emergency
14%
Others
14%
Poor
62%
Average
24%
Excellent
14%
Sleepiness
33%
Dizziness
33%
No Side Effect
33%
With or without food
33%
With food
33%
Empty stomach
33%
Not Expensive
67%
Average
33%

Patient concerns

What is heart attack? When heart attack coming?

Dr. Nabajit Talukdar
Dr. Nabajit Talukdar
Interventional Cardiology
Related to chest pain angina commonly

I am having pain in left side of the chest also in left arm is it related to heart attack what can be done get relief ??

Dr. Manju Singh
Dr. Manju Singh
Homeopathy
Please consult to your nearest doctor for blood pressure examination. then let me know.
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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Country of origin: India
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