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Duloxee-P 75 Capsule DR

Written By Dr. Anuj Saini, MMST, MBBS
Reviewed By Dr. Ashish Ranjan, MD (Pharmacology), MBBS
Last updated on 12 Nov 2024 | 01:11 AM (IST)
Duloxee-P 75 Capsule DR is used for the treatment of neuropathic pain. It decreases pain by controlling calcium channel activity of the nerve cells. It also increases the level of chemical messengers in the brain that helps maintain mental balance and stop the movement of pain signals in the brain.
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General Information

Contains

Pregabalin (75mg)+ Duloxetine (20mg)

Marketer

Talent India

Storage

Store below 30°C
The content is shown in English
Duloxee-P 75 Capsule DR image
Duloxee-P 75 Capsule DR image
Duloxee-P 75 Capsule DR image

Product introduction

Duloxee-P 75 Capsule DR can be taken with or without food. However, it is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration advised by your doctor as this is habit forming medicine. If you miss a dose of this medicine, take it as soon as you remember. Finish the full course of the treatment even if you feel better. It is important not to stop taking this medicine suddenly as it may worsen your symptoms.

Some common side effects of this medicine include peripheral edema, nausea, headache, dryness of mouth, difficulty in concentration and blurred vision. It may cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. This medicine may cause weight gain and to control it, you should have a balanced diet and exercise regularly. It is important to inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts.

Before taking this medicine let your doctor know if you suffer from kidney or liver disease. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

Uses of Duloxee-P Capsule DR

Side effects of Duloxee-P Capsule DR

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Duloxee-P
  • Nausea
  • Constipation
  • Insomnia (difficulty in sleeping)
  • Sleepiness
  • Headache
  • Dizziness
  • Tiredness
  • Ejaculation disorder
  • Erectile dysfunction
  • Uncoordinated body movements

How to use Duloxee-P Capsule DR

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Duloxee-P 75 Capsule DR may be taken with or without food, but it is better to take it at a fixed time.

How Duloxee-P Capsule DR works

Duloxee-P 75 Capsule DR is a combination of two medicines: pregabalin and duloxetine. Pregabalin decreases neurotransmitter release, while duloxetine boosts serotonin and norepinephrine levels to modulate pain perception, working together to relieve nerve pain.

Quick tips

  • Duloxee-P 75 Capsule DR is used for treating nerve pain caused by diabetes, shingles, fibromyalgia, and spinal cord injuries.
  • You may have to wait for 2 to 4 weeks before it starts working.
  • It may cause dizziness during the first few weeks. Don't drive or do anything requiring concentration until you know how Duloxee-P 75 Capsule DR affects you.
  • Avoid consuming alcohol when taking this medicine as it may cause excessive drowsiness and increase the risk of liver damage.
  • Monitor your blood pressure regularly, especially during the first month of treatment.
  • It may cause a sensation of restlessness or an inability to sit or stand still, especially when you first start taking it. Inform your doctor if this happens to you.
  • Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts or behavior.
  • Do not stop taking the medication suddenly without talking to your doctor.

Safety advice

Alcohol

Alcohol

UNSAFE
It is unsafe to consume alcohol with Duloxee-P 75 Capsule DR.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Duloxee-P 75 Capsule DR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Duloxee-P 75 Capsule DR is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving

Driving

UNSAFE
Duloxee-P 75 Capsule DR may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney

Kidney

CAUTION
Duloxee-P 75 Capsule DR should be used with caution in patients with kidney disease. Dose adjustment of Duloxee-P 75 Capsule DR may be needed. Please consult your doctor.
Liver

Liver

UNSAFE
Duloxee-P 75 Capsule DR is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.
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Fact Box

Habit Forming

No

Therapeutic Class

NEURO CNS

References

  1. Tesfaye S, Wilhelm S, Lledo A, et al. Duloxetine and pregabalin: High-dose monotherapy or their combination? The “COMBO-DN study” – a multinational, randomized, double-blind, parallel-group study in patients with diabetic peripheral neuropathic pain. Pain. 2013;154(12):2616-25. [Accessed 29 Apr. 2019] (online) Available from:
  2. Pregabalin. Vega Baja, Puerto Rico: Pfizer Pharmaceuticals LLC; 2009. [Accessed 23 Jan. 2019] (online) Available from:
  3. Duloxetine hydrochloride. Basingstoke, Hampshire: Eli Lilly and Company Limited; 2004 [revised 09 Nov. 2018]. [Accessed 23 Jan. 2019] (online) Available from:
  4. Pregablin. New York, New York: Pfizer; 2004 [revised Jun 2011]. [Accessed 22 Mar. 2019] (online) Available from:
  5. Medscape. Duloxetine. [Accessed 24 Apr. 2019] (online) Available from:
  6. Leeford Wellness. Pregabalin & Duloxetine [Product Information]. [Accessed 16 Sep. 2024] (online) Available from:
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Patient concerns

Headetch daily, no relieve. One pain killer daily i am taking.

Dr. Pushkar Mani
Dr. Pushkar Mani
Physician
Take hifenac p sos for pain

Dental problem premolar very p

Dr. Rohan Bhatt
Dr. Rohan Bhatt
Dental Surgery
Tab ketorol dt for painGo for x ray of tht tooth
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Talent India
Address: 1601, Karnavati Estate, GIDC, Phase III, Vatva, Ahmedabad 382445, Gujarat, India.

Vendor Details

Country of origin: India

Lab tests offered by us

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