Duron 150mg Injection

Written By Dr. Betina Chandolia, MDS, BDS

Reviewed By Dr. Ashish Ranjan, MD (Pharmacology), MBBS

Last updated on 12 Nov 2024 | 01:00 AM (IST)

Duron 150mg Injection is used to treat various types of serious irregular heartbeat (arrhythmia) such as fibrillation and tachycardia (increased heart rate). It is an anti-arrhythmic type of medicine which rapidly restores your heart to a steady and regular rhythm.

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1/2

3 ml Injection

General Information

Contains

Amiodarone (150mg)

Marketer

Samarth Life Sciences Pvt Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Duron 150mg Injection is given by a slow drip (infusion) into a vein under the supervision of a doctor. Continuous monitoring of blood pressure and heart rate may be needed while this medicine is administered. It is important that you keep having the injections until your doctor decides it is safe to stop them. After this, your doctor may prescribe tablets instead of the injection. If you stop taking this medicine, you may get dangerous uneven heartbeats, which can be life-threatening.

The most common side effects of this medicine include decreased blood pressure (hypotension), decreased heart rate (bradycardia), blurred vision, and application site reaction(pain, itching, and skin redness). This medicine can also cause problems with your liver, lungs, nerves, and thyroid gland. Ask your doctor what signs to look out for and report any symptoms you have. This medicine takes a long time to get cleared from the body. You may continue to have side effects after you stop using it. Ask your doctor about ways to prevent or reduce them.

Uses of Duron Injection

Arrhythmia

Benefits of Duron Injection

Arrhythmia
Duron 150mg Injection belongs to a group of medicines called anti-arrhythmics. It works by blocking abnormal electrical signals in the heart. This helps control the uneven beating of your heart and helps it to beat normally. It is normally only given by injection in a hospital when a fast response is needed or when tablets have not worked or cannot be given. This medicine thus prevents serious health problems that can sometimes be fatal and reduces your risk of death.

Side effects of Duron Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Duron

Decreased blood pressure
Slow heart rate
Blurred vision
Application site reactions (burning, irritation, itching and redness)

How to use Duron Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Duron Injection works

Duron 150mg Injection is an anti-arrhythmic medication. It regulates heart beat by blocking abnormal electrical signals in the heart.

All substitutes for Duron 150mg Injection

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Duron 150mg Injection may cause blurring of vision. Avoid driving or any activity requiring focus until you know how it affects you.
It makes your skin sensitive towards sunlight. Use a sunscreen and wear protective clothing while going out.
Your doctor may do regular blood tests, chest X-rays, ECG, eye test, thyroid, liver and lung function tests while you are taking this medicine.
Notify your doctor if you develop breathlessness, persistent cough, jaundice, restlessness, weight loss/gain or eye problems.
Notify your doctor about all other medicines that you are taking as Duron 150mg Injection can interact with many medicines.
Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

Safety advice

Alcohol

CAUTION

Caution is advised when consuming alcohol with Duron 150mg Injection. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Duron 150mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding

UNSAFE

Duron 150mg Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving

UNSAFE

Duron 150mg Injection may cause blurring of your vision for a short time just after its use. Do not drive until your vision is clear.

Kidney

SAFE IF PRESCRIBED

Duron 150mg Injection is safe to use in patients with kidney disease. No dose adjustment of Duron 150mg Injection is recommended.
However, inform your doctor if you have an underlying kidney disease.

Liver

CAUTION

Duron 150mg Injection should be used with caution in patients with liver disease. Dose adjustment of Duron 150mg Injection may be needed. Please consult your doctor.
Duron 150mg Injection may cause hepatic injury. Dose adjustment may be required.

Frequently asked questions

Does Duron 150mg Injection affect blood pressure?

Generally, an oral tablet of Duron 150mg Injection does not affect blood pressure. But, when given through an injection intravenously (in the vein) then it may decrease in the blood pressure. To prevent this your doctor or nurse may give Duron 150mg Injection slowly. Along with that, you may also be prescribed medicines which increase blood pressure (vasopressor agents) to the infusion.

What are the warning signals of liver toxicity caused by Duron 150mg Injection?

The warning signals of liver toxicity include yellowing of the skin or eyes (jaundice), tiredness, nausea, vomiting, dark-colored urine, pale-colored stools, loss of appetite, stomach pain or high temperature. Contact your doctor immediately if you experience these symptoms.

What kind of vision problems occur with Duron 150mg Injection?

You may experience blurred vision or see a circle around dazzling light (halos). It may also make your eyes dry or sensitive to light. It can even cause permanent blindness. Therefore, consult your doctor in case you experience any such problems while on Duron 150mg Injection.

What does Duron 150mg Injection do to the heart?

Duron 150mg Injection blocks certain electrical signals in the heart that can cause an irregular heartbeat (arrhythmia). This way, it helps to restore normal heart rhythm and maintains a regular, steady heartbeat.

Fact Box

Chemical Class

Benzofuran derivative

Habit Forming

Therapeutic Class

CARDIAC

Action Class

Class III Agents- anti arrhythmic

References

Sampson KJ, Kass RS. Anti-Arrhythmic Drugs. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 834-37.
Hume JR, Grant AO. Agents Used in Cardiac Arrhythmias. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 240-41.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 54-57.
Nattel S, Gersh BJ, Opie LH. Antiarrhythmic Drugs and Strategies. In: Opie LH, Gersh BJ, editors. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. pp. 288-95.
Amiodarone Hydrochloride [Prescribing Information]. Schaumburg, IL: Sagent Pharmaceuticals, Inc.; 2021. [Accessed 09 Jun, 2023] (online) Available from:
Drugs.com. Amiodarone Dosage. [Accessed 14 Mar. 2019] (online) Available from:
Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 14 Mar. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). Amiodarone. [Accessed 14 Mar. 2019] (online) Available from:

Patient concerns

The ecg report is Sinus Arrhythmia and short PR interval. What does it mean?

Dr. Nabajit Talukdar

Interventional Cardiology

Normal for d age

The ecg report is Sinus Arrhythmia and Short PR interval. What does it mean? What does it mean?

Dr. Nabajit Talukdar

Interventional Cardiology

Normal for 5 yrs

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Samarth Life Sciences Pvt Ltd
Address: Samarth House, 168, Bangur Nagar, Off Link Road, Near Ayappa Temple & Kallol Kali Temple, Goregaon (W), Mumbai - 400 090.

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Duron 150mg Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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