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Endokine 300mcg Injection

Filgrastim (300mcg)
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Cold stored
Stored between 2-8°C
Endokine 300mcg Injection is used to prevent infections after chemotherapy. It is a growth factor that stimulates the bone marrow to produce white blood cells. These cells protect the body against infections.

Written By Dr. Anuj Saini, MMST, MBBS,
Reviewed By Dr. Ashish Ranjan, MD (Pharmacology), MBBS,
Last updated on 12 Nov 2024 | 01:03 AM (IST)
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1 ml Injection
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Sep, 2026

 
 
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General Information

Contains

Filgrastim (300mcg)

Marketer

Intas Pharmaceuticals Ltd

Storage

Store in a refrigerator (2 - 8°C). Do not freeze.
The content is shown in English
Endokine 300mcg Injection image
Endokine 300mcg Injection image
Endokine 300mcg Injection image

Product introduction

Endokine 300mcg Injection is given as an injection by a qualified medical professional. You should continue to take as long as your doctor advises for it. The duration of treatment varies according to your need and response to treatment. You might be asked to get regular tests done to check the number of blood cells in your blood and your bone density level while you are taking this medicine.

The most common side effects of this medicine include bone pain, weakness, headache, and rash. Other than this, pain or redness at the site of injection is common. But, inform your doctor if you notice a lump, swelling, or bruising that does not go away. It might not prevent you from all kinds of infection, hence inform your doctor if you notice fever, chills, rash, sore throat, and swelling around the face or neck.

Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Uses of Endokine Injection

  • Prevention of Infections after chemotherapy

Benefits of Endokine Injection

Prevention of Infections after chemotherapy
Endokine 300mcg Injection increases the production of white blood cells by stimulating the immune system in our body. White blood cells are those cells that help us to fight infections. This medicine is really effective and must be used under medical supervision. Avoid being in crowds and wash your hands often to prevent any infections. Have plenty of fluids, unless otherwise advised by the doctor not to.

Side effects of Endokine Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Endokine
  • Bone pain
  • Weakness
  • Headache
  • Rash
  • Nausea
  • Increased lactate dehydrogenase level in blood
  • Vomiting
  • Increased uric acid level in blood
  • Oropharyngeal pain
  • Hair loss
  • Fatigue
  • Diarrhea
  • Constipation
  • Decreased appetite
  • Cough
  • Breathing problems
  • Injection site reactions (pain, swelling, redness)

How to use Endokine Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Endokine Injection works

Endokine 300mcg Injection is a growth factor that stimulates the bone marrow to produce white blood cells. These cells protect the body against infections. .

Quick tips

  • Endokine 300mcg Injection reduces the risk of infection in people treated with chemotherapy.
  • It is usually given as a daily injection into the tissue just under the skin or into the vein. 
  • You will normally receive your first dose at least 24 hours after your chemotherapy or bone marrow transplant.
  • Store it in the refrigerator, protect it from light, and don't shake it.
  • For a more comfortable injection, leave the syringe at room temperature for 30 minutes before using it.
  • Pain or redness in the area of injection is common. Let your doctor know if you notice a lump, swelling, or bruising that doesn't go away.
  • Use caution while driving or doing anything that requires concentration as Endokine 300mcg Injection may cause dizziness.
  • Your doctor may get regular tests done to monitor the number of blood cells in your blood, and your bone density level while you are receiving treatment with this medicine.
  • Stop taking Endokine 300mcg Injection and inform your doctor if you have a fever, shortness of breath, fast rate of breathing or trouble breathing.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Endokine 300mcg Injection. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Endokine 300mcg Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding

Breast feeding

SAFE IF PRESCRIBED
Endokine 300mcg Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving

Driving

UNSAFE
Endokine 300mcg Injection may cause side effects which could affect your ability to drive.
Endokine 300mcg Injection may cause fatigue. This may affect your driving ability.
Kidney

Kidney

SAFE IF PRESCRIBED
Endokine 300mcg Injection is safe to use in patients with kidney disease. No dose adjustment of Endokine 300mcg Injection is recommended.
Liver

Liver

SAFE IF PRESCRIBED
Endokine 300mcg Injection is safe to use in patients with liver disease. No dose adjustment of Endokine 300mcg Injection is recommended.

Frequently asked questions

Endokine 300mcg Injection is safe if used at prescribed doses for the prescribed duration as advised by your doctor.
Endokine 300mcg Injection works by stimulating the bone marrow (organ in the body where blood cells are produced) to increase the production of specific types of blood cells called neutrophils that help fight infections.
Endokine 300mcg Injection is used during cancer treatment (chemotherapy), bone marrow transplantation, severe chronic neutropenia (low number of a type of white blood cells called neutrophils), neutropenia in patients with HIV infection, and before stem cell donation.
No, Endokine 300mcg Injection does not cause cancer.
The exact cause in unknown, but bone pain is a common side-effect of Endokine 300mcg Injection.

Fact Box

Chemical Class

Granulocyte Colony-Stimulating Factor

Habit Forming

No

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Granulocyte-colony stimulating factor (G-CSF)

References

  1. Kaushansky K, Kipps TJ. Hematopoietic Agents: Growth Factors, Minerals, and Vitamins. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1074-75.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 545-46.
  3. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Filgrastim. [Updated 2019 Jun 3]. [Accessed 18 Feb. 2020] (online) Available from:
  4. Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Intas Pharmaceuticals Ltd
Address: Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Endokine 300mcg Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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