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Epalpex-M SR Tablet

Written By Dr. Betina Chandolia, MDS, BDS
Reviewed By Dr. Varun Gupta, MD Pharmacology, MBBS
Last updated on 28 Oct 2024 | 01:11 AM (IST)
Epalpex-M SR Tablet is a medicine used in the treatment of diabetic nerve disease. It protect the nerve fibers from damage and promotes regeneration of nerve cells. It is used along with other blood sugar lowering medications in order to prevent further nerve injury.
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General Information

Contains

Epalrestat (150mg)+ Methylcobalamin (1500mcg)

Marketer

Shilpex Pharmysis

Storage

Store below 30°C
The content is shown in English
Epalpex-M SR Tablet image

Product introduction

Epalpex-M SR Tablet may be taken with or without food, but you should try to take it at the same time every day. The dose will be decided by your doctor. Do not stop taking it without asking your doctor. If you do, your blood sugar levels may increase and put you at risk of serious complications like kidney damage and blindness. This medicine is only part of a treatment program that should include a healthy diet, regular exercise, and weight reduction as advised by your doctor.

The most common side effects of this medicine include nausea, vomiting, and increased liver enzymes. However, these are temporary and usually subside on their own. Please consult your doctor if these do not resolve or persist for a longer duration.

Before taking this medicine, inform your doctor if you have any kidney or liver problems or a urinary tract infection or if you are on water pills (diuretics). Pregnant or breastfeeding women should also consult their doctor before taking it. Avoid excessive alcohol intake while taking it as this may increase the risk of developing some side effects. Monitor your blood sugar levels regularly while taking this medicine.

Uses of Epalpex-M Tablet SR

Benefits of Epalpex-M Tablet SR

Diabetic nerve pain
Epalpex-M SR Tablet is a medicine used to treat long-lasting (chronic) pain caused by nerve damage due to diabetes. It reduces pain and its associated symptoms such as mood changes, sleep problems, and tiredness. It interferes with pain signals that travel through the damaged nerves and the brain and also improves nerve conduction. Taking Epalpex-M SR Tablet regularly will improve your physical and social functioning and overall quality of life.

Side effects of Epalpex-M Tablet SR

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Epalpex-M
  • Nausea
  • Vomiting
  • Increased liver enzymes

How to use Epalpex-M Tablet SR

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Epalpex-M SR Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Epalpex-M Tablet SR works

Epalpex-M SR Tablet is a combination of two medicines:.

All substitutes for Epalpex-M SR Tablet

For information purposes only. Consult a doctor before taking any medicine.

Nurestat-Plus Tablet SR

by Chemo Healthcare Pvt Ltd
₹33.9/tablet sr
33% costlier
<h3 class=bodySemiBold>Nurestat-Plus Tablet SR</h3>

Quick tips

  • Take it only as per the dose and duration prescribed by your doctor. 
  • Adherence to antidiabetic therapy can delay the onset of or prevent diabetic nerve disease.
  • Inform your doctor if you have:
    • Cut or sore on your feet that is infectious or not healing
    • Burning or tingling sensation in arm or feet that hamper your routine activities
    • Trouble in digestion, urination, or sexual functioning
    • Dizziness
  • To prevent diabetic nerve pain, wear proper footwear and examine your feet every day to detect lesions early.
  • Monitor your blood sugar level regularly.
  • Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

Safety advice

Alcohol

Alcohol

UNSAFE
It is unsafe to consume alcohol with Epalpex-M SR Tablet.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Epalpex-M SR Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Information regarding the use of Epalpex-M SR Tablet during breastfeeding is not available. Please consult your doctor.
Driving

Driving

CONSULT YOUR DOCTOR
It is not known whether Epalpex-M SR Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney

Kidney

CONSULT YOUR DOCTOR
There is limited information available on the use of Epalpex-M SR Tablet in patients with kidney disease. Please consult your doctor.
Liver

Liver

CONSULT YOUR DOCTOR
There is limited information available on the use of Epalpex-M SR Tablet in patients with liver disease. Please consult your doctor.
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Fact Box

Habit Forming

No

Therapeutic Class

ANTI DIABETIC

Related lab tests

Glycosylated Hemoglobin

References

  1. Sharma SR, Sharma N. Epalrestat, an aldose reductase inhibitor, in diabetic neuropathy: An Indian perspective. Ann Indian Acad Neurol. 2008;11(4):231-35. [Accecssed 08 Apr. 2019] (online) Available from:
  2. National Institues of Health. Vitamin B12. [Accessed 08 Apr. 2019] (online) Available from:
  3. Hotta N, Akanuma Y, Kawamori R, et al. Long-term clinical effects of epalrestat, an aldose reductase inhibitor, on diabetic peripheral neuropathy: the 3-year, multicenter, comparative Aldose Reductase Inhibitor-Diabetes Complications Trial. Diabetes Care. 2006;29(7):1538-44. [Accessed 08 Apr. 2019] (online) Available from:
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User feedback

Once A Day
78%
Twice A Day
22%

Patient concerns

My dad is a diabetic patient now a days he is also suffering from leg pains associated with nerve pains from back side of left leg. How do i over come with this kind of situation to reduce the pains and keep it normal.

Dr. Sanjay Bhatt
Dr. Sanjay Bhatt
Physician
Good sugar control and Tab. Pregastar M

I have sholder pain, my local doctor told diabetic person muscle got tight, go to physiyotheraphy

Dr. Mehtab Baig
Dr. Mehtab Baig
Orthopaedic Physiotherapy
Yes, go nearest physiotherapy clinicI m from lucknow
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Shilpex Pharmysis
Address: A-1, Ground Floor, Fie, Patparganj, New Delhi , New Delhi

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Epalpex-M SR Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's â„ž and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

Lab tests offered by us

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Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945
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