Fleta Bolus 20mg Injection
Written By Dr. Balshine Singh Kanwar, MD, MBBS
Reviewed By Dr. Ashish Ranjan, MD (Pharmacology), MBBS
Last updated on 12 Nov 2024 | 01:11 AM (IST)
Fleta Bolus 20mg Injection is a blood thinner which prevents formation of harmful blood clots. It is used in the treatment of a heart attack and also prevents the clotting of blood in the heart during an angioplasty (procedure to improve blood flow to the heart).
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General Information
Contains
Eptifibatide (20mg)
Marketer
Lupin Ltd
Storage
Store in a refrigerator (2 - 8°C). Do not freeze.
The content is shown in English


Product introduction
Fleta Bolus 20mg Injection is administered under the supervision of a doctor. Your doctor will decide the dose and duration of the medicine for you. You should continue all your other medicines that are advised by the doctor for your long-term treatment even after this injection.
Use of this medicine may cause low blood platelets and increase your risk of bleeding. Let your doctor know immediately if you see pinpoint rash or blood in your vomits, urine, or stool. It may also cause low blood pressure as a side effect. Your doctor will explain the benefits and risks associated with this medicine before it is administered.
This medicine is used with caution for some people. Before taking it, you must inform the doctor if you are suffering from any bleeding disorder, kidney or liver disease. Also, let your doctor know if you are pregnant or breastfeeding and about all the other medications that you are taking regularly.
Use of this medicine may cause low blood platelets and increase your risk of bleeding. Let your doctor know immediately if you see pinpoint rash or blood in your vomits, urine, or stool. It may also cause low blood pressure as a side effect. Your doctor will explain the benefits and risks associated with this medicine before it is administered.
This medicine is used with caution for some people. Before taking it, you must inform the doctor if you are suffering from any bleeding disorder, kidney or liver disease. Also, let your doctor know if you are pregnant or breastfeeding and about all the other medications that you are taking regularly.
Uses of Fleta Bolus Injection
- Unstable angina
- Prevention of Blood clots
- Prevention of Heart attack
Benefits of Fleta Bolus Injection
Prevention of Blood clots
Fleta Bolus 20mg Injection prevents new blood clots from forming and prevents the existing ones from getting bigger. It works by blocking a substance in the body which is involved in blood clotting. Thus it helps your blood flow smoothly throughout the body. This can help reduce damage caused by clots in your lungs (pulmonary embolism), brain (stroke), heart (heart attack) or other blood vessels (thrombosis).
Fleta Bolus 20mg Injection prevents new blood clots from forming and prevents the existing ones from getting bigger. It works by blocking a substance in the body which is involved in blood clotting. Thus it helps your blood flow smoothly throughout the body. This can help reduce damage caused by clots in your lungs (pulmonary embolism), brain (stroke), heart (heart attack) or other blood vessels (thrombosis).
Prevention of Heart attack
It prevents blood from clotting inside the veins and arteries. This helps the blood flow freely around your body thereby preventing a heart attack or stroke (or deep vein thrombosis or pulmonary embolism). Follow your doctor’s instructions carefully and make appropriate lifestyle changes (such as eating healthy and staying active) to maximize the effectiveness of this medicine.
It prevents blood from clotting inside the veins and arteries. This helps the blood flow freely around your body thereby preventing a heart attack or stroke (or deep vein thrombosis or pulmonary embolism). Follow your doctor’s instructions carefully and make appropriate lifestyle changes (such as eating healthy and staying active) to maximize the effectiveness of this medicine.
Side effects of Fleta Bolus Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Fleta Bolus
- Bleeding
- Decreased blood pressure
How to use Fleta Bolus Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Fleta Bolus Injection works
Fleta Bolus 20mg Injection is an antiplatelet medication. It works by preventing the platelets from sticking together, thereby decreasing the formation of harmful blood clots.
All substitutes for Fleta Bolus 20mg Injection
For information purposes only. Consult a doctor before taking any medicine.
Quick tips
- It is usually given by your nurse or doctor as an infusion (drip) into a vein.
- It increases your risk of bleeding. Be careful while shaving, cutting fingernails or toenails or using sharp objects.
- Notify your doctor if you see blood in your vomit, urine or stool (black, tarry stools or bright red blood).
Safety advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Fleta Bolus 20mg Injection. Please consult your doctor.

Pregnancy
SAFE IF PRESCRIBED
Fleta Bolus 20mg Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Breast feeding
CAUTION
Fleta Bolus 20mg Injection should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.

Driving
NOT RELEVANT
Not relevant, as Fleta Bolus 20mg Injection is intended for use in hospitalised patients.

Kidney
CAUTION
Fleta Bolus 20mg Injection should be used with caution in patients with kidney disease. Dose adjustment of Fleta Bolus 20mg Injection may be needed. Please consult your doctor.
Use of Fleta Bolus 20mg Injection is not recommended in patients with severe kidney disease.
Use of Fleta Bolus 20mg Injection is not recommended in patients with severe kidney disease.

Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Fleta Bolus 20mg Injection in patients with liver disease. Please consult your doctor.
Use of Fleta Bolus 20mg Injection is not recommended in patients with severe liver disease.
Use of Fleta Bolus 20mg Injection is not recommended in patients with severe liver disease.
Frequently asked questions
Yes, Fleta Bolus 20mg Injection increases the risk of bleeding. Always be careful while doing activities that may cause an injury or bleeding. Tell your doctor immediately if you notice any abnormal bruising or bleeding.
Fleta Bolus 20mg Injection can interact with several medicines. Do not take any medicine without talking to your doctor.
Fleta Bolus 20mg Injection reduces your risk of developing blood clots in the blood vessels of your leg, lungs, heart and brain. You may not feel any difference after taking Fleta Bolus 20mg Injection. However, keep taking this medicine as prescribed by your doctor because you will still be getting its full benefits.
Fact Box
Chemical Class
Amino acids, Peptides analogues
Habit Forming
No
Therapeutic Class
BLOOD RELATED
Action Class
Glycoprotein IIb/IIIa Inhibitors
References
- Weitz JI. Blood Coagulation and Anticoagulant, Fibrinolytic, and Antiplatelet Drugs. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 871.
- Fox KA, White HD, Gersh BJ, et al. Antithrombotic Agents: Platelete Inhibitors, Acute Anticoagulants, Fibrinolytics, and Chronic Anticoagulants. In: Opie LH, Gersh BJ, editors. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. pp. 355-56.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 485-46.
- Eptifibatide. Ferentino, Italy: Patheon Italia S.p.A.; 1998 [revised Mar. 2013]. [Accessed 18 Mar. 2019] (online) Available from:
- Drugs.com. Eptifibatide Pregnancy and Breastfeeding Warnings. [Accessed 18 Mar. 2019] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). Eptifibatide. [Accessed 18 Mar. 2019] (online) Available from:
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Patient concerns
What is heart attack? When heart attack coming?
Dr. Nabajit Talukdar
Interventional Cardiology
Related to chest pain angina commonly
mild heart attack few weeks ago. Coronary Artery Disease - Unstable Angina, Anterior Lateral Wall Ischemia, Mild LV Dysfunctional(EF-52%), Mild to Moderate AR, Mild PAH, TROP - I Positive
Dr. Deepak Kumar Soni
Ayurveda
Hi Kindly consult to Ayurvedic doctor at your local city area , face to face consult is needed.
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
Marketer details
Name: Lupin Ltd
Address: 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India
Address: 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India
Vendor Details
Country of origin: India
Lab tests offered by us
- CBC (Complete Blood Count)
- FBS (Fasting Blood Sugar)
- Thyroid Profile Total (T3, T4 & TSH)
- HbA1c (Glycosylated Hemoglobin)
- Glucose - Postprandial
- Lipid Profile
- Vitamin D (25-Hydroxy)
- Urine R/M (Urine Routine & Microscopy)
- Coronavirus Covid-19 Test (RT-PCR technique)
- LFT (Liver Function Test)
- Kidney Function Test
- TSH (Thyroid Stimulating Hormone) Ultrasensitive
- ESR (Erythrocyte Sedimentation Rate)
- Uric Acid
- Vitamin B12
- C- Reactive Protein Quantitative
- Urine Culture and Sensitivity
- Serum Electrolyte
- Serum Calcium
- Creatinine
- Diabetes Screening
- KFT with Electrolytes (Kidney Function Test with Electrolytes)
- Cholesterol - Total
- Hemoglobin
- Complete Haemogram
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