Fos-Aprepitant 125mg Tablet
Written By Dr. Betina Chandolia, MDS, BDS
Reviewed By Dr. Lalit Kanodia, MBA, MD Pharmacology
Last updated on 11 Nov 2024 | 01:05 AM (IST)
Fos-Aprepitant 125mg Tablet is a prescription medicine used to prevent nausea and vomiting caused by chemotherapy. It is also used in the prevention of postoperative nausea and vomiting in adults.
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General Information
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Product introduction
Fos-Aprepitant 125mg Tablet is taken with or without food in a dose and duration as advised by the doctor. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen. Let your doctor know about all other medications you are taking as some may affect, or be affected by this medicine.
The most common side effects are headache, hiccups, loss of appetite, fatigue, and constipation. Most of these are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any of these side effects. This medicine may cause diarrhea, so it is beneficial to drink plenty of fluids while taking this medicine as it may help to prevent dehydration. It may also cause dizziness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Avoid drinking alcohol while taking this medicine as it can worsen your sleepiness.
Before taking this medicine, you should tell your doctor if you are pregnant, planning a pregnancy, or breastfeeding. You should tell your doctor if you have any kidney or liver diseases so that your doctor can prescribe a suitable dose for you.
The most common side effects are headache, hiccups, loss of appetite, fatigue, and constipation. Most of these are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any of these side effects. This medicine may cause diarrhea, so it is beneficial to drink plenty of fluids while taking this medicine as it may help to prevent dehydration. It may also cause dizziness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Avoid drinking alcohol while taking this medicine as it can worsen your sleepiness.
Before taking this medicine, you should tell your doctor if you are pregnant, planning a pregnancy, or breastfeeding. You should tell your doctor if you have any kidney or liver diseases so that your doctor can prescribe a suitable dose for you.
Uses of Fos-Aprepitant Tablet
- Nausea and vomiting due to chemotherapy
Side effects of Fos-Aprepitant Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Fos-Aprepitant
- Headache
- Dizziness
- Hiccup
- Loss of appetite
- Fatigue
- Constipation
- Diarrhea
How to use Fos-Aprepitant Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Fos-Aprepitant 125mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
How Fos-Aprepitant Tablet works
Fos-Aprepitant 125mg Tablet is an antiemetic medication. It works by blocking the action of a chemical messenger (neurokinin) in the brain that may cause nausea and vomiting during anti-cancer treatment (chemotherapy).
Quick tips
- Fos-Aprepitant 125mg Tablet helps prevent nausea and vomiting caused by certain chemotherapy medicines.
- It will not help if you already have nausea and vomiting.
- Do not use it continuously for a long time.
- It is recommended to take Fos-Aprepitant 125mg Tablet 1 hour before chemotherapy treatment (Day 1) and in the morning on Days 2 and 3.
- It may damage sperms and may harm the baby if used during pregnancy or breastfeeding.
Safety advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Fos-Aprepitant 125mg Tablet. Please consult your doctor.

Pregnancy
CONSULT YOUR DOCTOR
Fos-Aprepitant 125mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding
CONSULT YOUR DOCTOR
Fos-Aprepitant 125mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving
UNSAFE
Fos-Aprepitant 125mg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney
SAFE IF PRESCRIBED
Fos-Aprepitant 125mg Tablet is safe to use in patients with kidney disease. No dose adjustment of Fos-Aprepitant 125mg Tablet is recommended.

Liver
SAFE IF PRESCRIBED
Fos-Aprepitant 125mg Tablet is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Fos-Aprepitant 125mg Tablet may not be needed in these patients. Please consult your doctor.
Frequently asked questions
Fos-Aprepitant 125mg Tablet is used in adults in combination with other medicines to prevent nausea and vomiting caused by chemotherapy (cancer treatment) or in some cases after a surgery
Fos-Aprepitant 125mg Tablet is an antiemetic that works by blocking the action of neurokinin, a natural substance in the brain that causes nausea and vomiting.
Fact Box
Chemical Class
Phenylmorpholine Derivative
Habit Forming
No
Therapeutic Class
GASTRO INTESTINAL
Action Class
Neurokinin-1 (NK1) Receptor Antagonists
References
- McQuaid KR. Drugs Used in the Treatment of Gastrointestinal Diseases. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 1086.
- Aprepitant. [Accessed 28 Mar. 2019] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 28 Mar. 2019] (online) Available from:

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
Marketer details
Name: Fulford India Ltd
Address: Plot No. -810, Sector - 3 , Industrial Area , Pthampur Dist. Dhar - 454 775 (M.P.) India
Address: Plot No. -810, Sector - 3 , Industrial Area , Pthampur Dist. Dhar - 454 775 (M.P.) India
Vendor Details
Country of origin: India
A licensed vendor partner from your nearest location will deliver Fos-Aprepitant 125mg Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
A licensed vendor partner from your nearest location will deliver Fos-Aprepitant 125mg Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
In case of any issues, contact us
Email ID: [email protected]Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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