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Fostirel 300IU Injection

Written By Dr. Betina Chandolia, MDS, BDS
Reviewed By Dr. Lalit Kanodia, MBA, MD Pharmacology
Last updated on 11 Nov 2024 | 01:01 AM (IST)
Fostirel 300IU Injection is used in the treatment of infertility in women. It is also helpful in the treatment of male hypogonadism (delayed puberty, and low sperm count). It works by releasing the eggs from the ovary in women and by increasing the testosterone level in men.
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General Information

Contains

Recombinant follicle stimulating hormone (300IU)

Marketer

Reliance Life Sciences

Storage

Store in a refrigerator (2 - 8°C). Do not freeze.
The content is shown in English
Fostirel 300IU Injection image

Product introduction

Fostirel 300IU Injection is given as an injection under the supervision of a doctor. Your doctor will decide the right time to take the injection, so always follow your doctor's advice. The dose and how often you take it depends on what you are taking it for. You should take this medicine for as long as it is prescribed for you.

The most common side effects of this medicine include allergic reactions, headache, swelling of the breast in males, and acne. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them.

Before taking this medicine, tell your doctor if you have ever had heart disease, or had an ovarian cyst, or had thyroid gland disorder. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Tell your doctor if you are pregnant or breastfeeding. You should avoid alcohol or have to follow doctor advice related to diet while taking this medicine.

Uses of Fostirel Injection

Benefits of Fostirel Injection

Female infertility
Fostirel 300IU Injection helps in normal development of an egg in a woman's ovary (female reproductive organ), and stimulates the release of a healthy, matured egg. This helps to treat infertility in women and increases the chance of a successful pregnancy. It is given as an injection by a doctor or nurse and should not be self-administered. You should use the medicine as prescribed for it to be effective.
Male hypogonadism
Male Hypogonadism is the improper functioning of reproductive organs, that is, testes in males, which causes failure to produce sex hormones required for fertility. Fostirel 300IU Injection acts as the male sex hormone, testosterone and therefore, improves sperm production in males. This can reduce infertility and helps to treat hypogonadism in males. Follow your doctor’s instructions carefully to get the most benefit.

Side effects of Fostirel Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Fostirel
  • Injection site allergic reaction
  • Headache
  • Acne
  • Swelling of breast in male
  • Abdominal pain
  • Gastrointestinal discomfort
  • Ovarian cysts
  • Rash

How to use Fostirel Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Fostirel Injection works

Fostirel 300IU Injection is a hormone. In females, it works by stimulating the release of estrogen which helps in the growth and development of the egg before release. In males, it helps in the production of sperms.

Quick tips

  • It may also be used to stimulate sperm formation in men.
  • The injection is administered under the skin. Follow the recommended dosage and monitoring schedules to minimise the possibility of ovarian hyperstimulation.
  • Inform your doctor immediately if you have severe pelvic pain, nausea, vomiting, diarrhea, sudden weight gain, trouble breathing, or decreased or no urination during treatment, as these could be symptoms of ovarian hyperstimulation syndrome (OHSS).
  • Do not use Fostirel 300IU Injection if you are already pregnant or breastfeeding.
  • Fostirel 300IU Injection stimulates the production of eggs in women undergoing treatment for infertility.
  • Your doctor may prescribe more than one medicine as part of your suggested pregnancy plan.
  • Pregnancy following treatment with Fostirel 300IU Injection is more likely to result in a multiple pregnancy (twins or more).

Safety advice

Alcohol

Alcohol

CAUTION
Caution is advised when consuming alcohol with Fostirel 300IU Injection. Please consult your doctor.
Pregnancy

Pregnancy

UNSAFE
Fostirel 300IU Injection is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Information regarding the use of Fostirel 300IU Injection during breastfeeding is not available. Please consult your doctor.
Driving

Driving

SAFE
Fostirel 300IU Injection does not usually affect your ability to drive.
Kidney

Kidney

CONSULT YOUR DOCTOR
There is limited information available on the use of Fostirel 300IU Injection in patients with kidney disease. Please consult your doctor.
Liver

Liver

CONSULT YOUR DOCTOR
There is limited information available on the use of Fostirel 300IU Injection in patients with liver disease. Please consult your doctor.
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Frequently asked questions

Fostirel 300IU Injection contains Follitropin alfa which is a type of Follicle Stimulating Hormone produced naturally by the body. It is used in women who are unable to ovulate. It works by stimulating the growth of follicles (which contain eggs) in the ovary. This helps in the release of a properly developed egg at the time of ovulation. It is also used in assisted reproductive technology (ART) procedures such as in-vitro fertilization (IVF), which help women to become pregnant. It may also be used in adult men who are infertile due to lack of certain hormones and inability to produce enough sperm cells.
Fostirel 300IU Injection is an injection given subcutaneously (just under the skin). The dose and treatment duration depend on the ovarian response of the patient.
Ideally, you should try not to miss a dose of Fostirel 300IU Injection. However, please talk to your doctor as soon as you remember that you have missed a dose.
The most common side effect is a local site reaction at the injection site (pain, redness, swelling, and irritation). The other common side effects are a headache, ovarian cysts, abdominal pain or cramping, nausea, vomiting, diarrhea and bloating. If any of these side effects bother you, please consult with your doctor. In addition, this medicine may increase the likelihood of conditions like ovarian hyperstimulation syndrome (OHSS), multiple pregnancy or miscarriage.

Fact Box

Chemical Class

Gonadotropins

Habit Forming

No

Therapeutic Class

GYNAECOLOGICAL

Action Class

Gonadotropins

References

  1. Parker KL, Schimmer BP. Introduction To Endocrinology: The Hypothalamic-Pituitary Axis. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1117-120.
  2. Masters SB. Hypothalamic & Pituitary Hormones. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 650-53.
  3. Mayo Clinic. Follitropin alfa. [Accessed 03 Apr. 2019] (online) Available from:
  4. OLLISTIM AQ Cartridge (follitropin beta injection). Ravensburg, Germany: Vetter Pharma-Fertigung GmbH & Co. KG; 1997 [revised Jun. 2010]. [Accessed 28 Jan. 2019] (online) Available from:
  5. Follitropin alfa. Rockland, Massachusetts: SERONO, INC. [Accessed 03 Apr. 2019] (online) Available from:
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Patient concerns

Treatment for male infertility

Dr. Asmita Kaundal
Dr. Asmita Kaundal
Obstetrics and Gynaecology
its a vast topic treatment depends on the cause . kindly see an andrologist for detailed evaluation

Male infertility-low sperm motility

Dr. Saurav Arora
Dr. Saurav Arora
Homeopathy
Dear sir for this condition you need to visit a sexologist
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Reliance Life Sciences
Address: Dhirubhai Ambani Life Sciences Centre, R-282, TTC Area of MIDC, Thane-Belapur Road, Rabale, Navi Mumbai 400 701

Vendor Details

Country of origin: India
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