Frisium 2.5mg Syrup
Written By Dr. Swati Mishra, BDS
Reviewed By Dr. Khushbu Goel, DM, MD
Last updated on 12 Nov 2024 | 01:12 AM (IST)
Frisium 2.5mg Syrup belongs to a class of medicines known as benzodiazepines. It is used to treat epilepsy (seizures) and severe anxiety. It works by suppressing the abnormal and excessive activity of the nerve cells in the brain.
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General Information
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Product introduction
Frisium 2.5mg Syrup may be taken with or without food. However, it is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration as advised by your doctor as it has a high potential of habit-forming.
If you have missed a dose, take it as soon as you remember and finish the full course of treatment even if you feel better. It is important that this medication is not stopped suddenly without talking to your doctor as it may increase seizure frequency.
Some common side effects of this medicine include tiredness, slurred speech, fever, cough, drooling, constipation, and difficulty in passing urine. It may cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. It is important to consult the doctor if you notice blisters on the skin or inside your mouth. If you have been taking this medicine for a long time then regular monitoring of blood and liver functions may be required.
If you have missed a dose, take it as soon as you remember and finish the full course of treatment even if you feel better. It is important that this medication is not stopped suddenly without talking to your doctor as it may increase seizure frequency.
Some common side effects of this medicine include tiredness, slurred speech, fever, cough, drooling, constipation, and difficulty in passing urine. It may cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. It is important to consult the doctor if you notice blisters on the skin or inside your mouth. If you have been taking this medicine for a long time then regular monitoring of blood and liver functions may be required.
Uses of Frisium Syrup
Benefits of Frisium Syrup
Treatment of Epilepsy/Seizures
Frisium 2.5mg Syrup slows down electrical signals in the brain that cause seizures (fits). It can also help reduce symptoms of seizures, such as confusion, uncontrollable jerking movements, loss of awareness, and fear or anxiety. This medicine can allow you to do some activities that you would otherwise be forbidden or scared to do (such as swimming and driving). It can take a few weeks for this medicine to work (because the dose has to be increased slowly) and during this time you may still have seizures. Therefore, do not stop using this medicine even if you feel well, until your doctor advises you to. Missing doses may trigger a seizure.
Frisium 2.5mg Syrup slows down electrical signals in the brain that cause seizures (fits). It can also help reduce symptoms of seizures, such as confusion, uncontrollable jerking movements, loss of awareness, and fear or anxiety. This medicine can allow you to do some activities that you would otherwise be forbidden or scared to do (such as swimming and driving). It can take a few weeks for this medicine to work (because the dose has to be increased slowly) and during this time you may still have seizures. Therefore, do not stop using this medicine even if you feel well, until your doctor advises you to. Missing doses may trigger a seizure.
Treatment of Severe anxiety
Frisium 2.5mg Syrup reduces the symptoms of excessive anxiety and worry. It can also reduce feelings of restlessness, tiredness, difficulty concentrating, and irritability. Therefore, it helps one to go about their daily activities more easily and be more productive. Keep taking this medicine even if you feel well. Stopping it suddenly can cause serious problems; so, do not stop taking it without discussing with the doctor.
Frisium 2.5mg Syrup reduces the symptoms of excessive anxiety and worry. It can also reduce feelings of restlessness, tiredness, difficulty concentrating, and irritability. Therefore, it helps one to go about their daily activities more easily and be more productive. Keep taking this medicine even if you feel well. Stopping it suddenly can cause serious problems; so, do not stop taking it without discussing with the doctor.
Side effects of Frisium Syrup
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Frisium
- Constipation
- Sleepiness
- Depression
- Dizziness
- Dryness in mouth
- Fatigue
- Headache
- Nausea
- Sedation
- Speech disorder
- Decreased appetite
- Irritability
- Aggression
- Restlessness
- Drug tolerance
- Difficulty in paying attention
- Tremors
- Abnormality of voluntary movements
How to use Frisium Syrup
Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. Frisium 2.5mg Syrup may be taken with or without food, but it is better to take it at a fixed time.
How Frisium Syrup works
Frisium 2.5mg Syrup is a benzodiazepine. It works by increasing the action of a chemical messenger (GABA) which suppresses the abnormal and excessive activity of the nerve cells in the brain.
Quick tips
- The addiction / habit-forming potential of this medicine is very high. Take it only as per the dose and duration advised by your doctor
- It may cause dizziness. Do not drive or do anything that requires mental focus until you know how this medicine affects you.
- Avoid consuming alcohol as it may increase dizziness and drowsiness.
- Inform your doctor if you are pregnant, planning to conceive or breastfeeding.
- Inform your doctor if you notice sores or blisters on your skin, lips, or inside your mouth.
- Do not stop taking medication suddenly without talking to your doctor as that may lead to nausea, anxiety, agitation, flu-like symptoms, sweating, tremor, and confusion.
Safety advice

Alcohol
UNSAFE
Frisium 2.5mg Syrup may cause excessive drowsiness with alcohol.

Pregnancy
CONSULT YOUR DOCTOR
Frisium 2.5mg Syrup may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding
CONSULT YOUR DOCTOR
Frisium 2.5mg Syrup is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Short-term use is not expected to cause any adverse effects in the breastfed baby, especially if the baby is older than 2 months. During long-term use, monitor for possible sleepiness.
Short-term use is not expected to cause any adverse effects in the breastfed baby, especially if the baby is older than 2 months. During long-term use, monitor for possible sleepiness.

Driving
UNSAFE
Frisium 2.5mg Syrup may cause side effects which could affect your ability to drive.
You may feel sleepy or have concentration or memory problems after taking Frisium 2.5mg Syrup and this may affect your ability to drive.
You may feel sleepy or have concentration or memory problems after taking Frisium 2.5mg Syrup and this may affect your ability to drive.

Kidney
CAUTION
Frisium 2.5mg Syrup should be used with caution in patients with kidney disease. Dose adjustment of Frisium 2.5mg Syrup may be needed. Please consult your doctor.
Limited information is available on the use of Frisium 2.5mg Syrup in these patients. No dose adjustment is recommended in patients with mild to moderate kidney disease.
Limited information is available on the use of Frisium 2.5mg Syrup in these patients. No dose adjustment is recommended in patients with mild to moderate kidney disease.

Liver
CAUTION
Frisium 2.5mg Syrup should be used with caution in patients with liver disease. Dose adjustment of Frisium 2.5mg Syrup may be needed. Please consult your doctor.
Limited information is available on use of Frisium 2.5mg Syrup in patients with severe liver disease.
Limited information is available on use of Frisium 2.5mg Syrup in patients with severe liver disease.
Frequently asked questions
Yes, Frisium 2.5mg Syrup can be habit forming if used for a long time. The risk of dependence increases with dose and duration of treatment; it is also greater in patients with a history of alcohol or drug abuse. Therefore, the duration of treatment is generally as short as possible.
Yes, Frisium 2.5mg Syrup can make you sleepy. It usually begins within the first month of treatment and may diminish with continued treatment.
Frisium 2.5mg Syrup is a fast-acting medicine, which means that it quickly gets absorbed from the bloodstream. Frisium 2.5mg Syrup reaches its highest blood levels within half an hour to 4 hours after the dose is taken.
No, Frisium 2.5mg Syrup and clonazepam are not the same medicines but belong to the same class of drugs known as benzodiazepines.
Withdrawal syndrome may develop at any time up to 3 weeks after stopping Frisium 2.5mg Syrup. Withdrawal signs may last anywhere from 4 weeks to a year or more.
No, do not stop taking Frisium 2.5mg Syrup even if you are feeling well, unless your doctor tells you to. Suddenly stopping Frisium 2.5mg Syrup may cause unwanted effects known as withdrawal symptoms. To prevent this, the dose of clobazam needs to be reduced gradually before completely stopping it. Therefore, it is important that you consult your doctor first.
Taking more than the recommended doses of Frisium 2.5mg Syrup can affect in different ways, and the patient should seek immediate medical help. In mild cases, it may cause symptoms such as drowsiness, mental confusion, and tiredness. Whereas, in more serious cases, the symptoms may include the complete loss of control of bodily movements, decreased muscle tone, low blood pressure, respiratory depression, coma in rare cases, and death in very rare cases.
Generally, the use of Frisium 2.5mg Syrup does not cause a decrease in the blood pressure, but taking more than the recommended doses of Frisium 2.5mg Syrup may cause a fall in the blood pressure
Frisium 2.5mg Syrup may cause tiredness along with muscle weakness. In case you experience tiredness or if tiredness persists for a long time, then you should consult your doctor.
No, Frisium 2.5mg Syrup dose not cause depression, but it can cause recurrence of pre-existing depression.
Fact Box
Chemical Class
Benzodiazepines Derivative
Habit Forming
Yes
Therapeutic Class
NEURO CNS
Action Class
Benzodiazepines
References
- Porters RJ, Meldrum BS. Antiseizure Drugs. Sedative-Hypnotic Drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 415.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 293-94.
- Clobazam. Winchester, Kentucky: Catalent Pharma Solutions, LLC; 2011 [revised Jun. 2018]. [Accessed 19 Jun. 2019] (online) Available from:
- Drugs.com. Clobazam Pregnancy and Breastfeeding Warnings. [Accessed 22 Mar. 2019] (online) Available from:
- Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Clobazam. [Updated 2019 Oct 23]. [Accessed 20 Feb. 2020] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 20 Mar. 2019] (online) Available from:
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Patient concerns
Epilepsy disorder for the past 7-8 years. Are contraceptive pills safe for epileptic patients Lamitor 25,50 and 100 epilive 500 Frisium 20 and frisium 5
Dr. Vikas Sharma
Neurology
per se epileptic ptinets can take contrcep pillswith these medicines; interaction is unlukelystill better talk to the gynec for other optionswheteher u hav epilepsy or not, pills are effective but can sometimes cause side effects due to hormonal effcets; personally i wud suggest barrier methods
My father got paralysis stroke in april 2016 Now am giving him ecosprin av 150 telsarton 80 frisium 10 levera 150 eptoin 100 I feel doses going to much . In the morning 4 tablet and in the evening 5 tablets
Dr. Vikas Sharma
Neurology
Frisium can be withdrawn Show to neurologist
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