Graincide Tablet SR
Written By Dr. Betina Chandolia, MDS, BDS
Reviewed By Dr. Shilpa Garcha, MD (Pharmacology), MBBS
Last updated on 12 Nov 2024 | 01:11 AM (IST)
Graincide Tablet SR is a combination of two medicines that helps in preventing migraine. This medicine is not used for treatment of acute migraine attack.
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1/2
10 tablet sr
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General Information
Contains
Propranolol (40mg)+ Flunarizine (10mg)
Marketer
Synovia Life Sciences Pvt Ltd
Storage
Store below 30°C
The content is shown in English



Product introduction
Graincide Tablet SR should be taken on empty stomach, but try to have it same time regularly at a fixed time preferably at night. The dose and how often you take it depends on what you are taking it for. Your doctor will decide how much you need to improve your symptoms. You should take this medicine for as long as it is prescribed for you. Lifestyle modifications like avoiding stress, smoking, and processed food items may help this medicine work better.
Few common side effects of this medicine include weight gain, slow heart rate, tiredness, depression, drowsiness and cold extremities. It may cause sleepiness so try not to drive or do anything that requires mental focus or rise slowly while from sitting position. The drug has the ability to hide the symptoms of the blood sugar level, hence monitor your blood sugar level regularly as well as blood pressure while taking this medicine.
Before taking this medicine, let your doctor know if you have liver or kidney, or depression disease, or if you are pregnant or breastfeeding. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works.
Few common side effects of this medicine include weight gain, slow heart rate, tiredness, depression, drowsiness and cold extremities. It may cause sleepiness so try not to drive or do anything that requires mental focus or rise slowly while from sitting position. The drug has the ability to hide the symptoms of the blood sugar level, hence monitor your blood sugar level regularly as well as blood pressure while taking this medicine.
Before taking this medicine, let your doctor know if you have liver or kidney, or depression disease, or if you are pregnant or breastfeeding. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works.
Uses of Graincide Tablet SR
Benefits of Graincide Tablet SR
Prevention of Migraine
Graincide Tablet SR helps improve the flow of blood in your brain and prevents abnormal activity of muscles that triggers migraines. It is a very effective medicine for preventing migraine attacks, however, it does not treat an attack that has already started. By preventing and reducing the frequency migraine attacks, the medicine can help you carry out your daily activities and improve your quality of life.
Graincide Tablet SR helps improve the flow of blood in your brain and prevents abnormal activity of muscles that triggers migraines. It is a very effective medicine for preventing migraine attacks, however, it does not treat an attack that has already started. By preventing and reducing the frequency migraine attacks, the medicine can help you carry out your daily activities and improve your quality of life.
Side effects of Graincide Tablet SR
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Graincide
- Weight gain
- Slow heart rate
- Tiredness
- Depression
- Drowsiness
- Abnormal dreams
- Cold extremities
How to use Graincide Tablet SR
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Graincide Tablet SR is to be taken empty stomach.
How Graincide Tablet SR works
Graincide Tablet SR is a combination of two medicines: Propranolol and Flunarizine, which prevents migraine. Propranolol is a beta blocker and Flunarizine is a calcium channel blocker. They work by stabilizing the reactive nerve cells and increasing the threshold to migraine activation. They also inhibit cortical spreading depression (CSD- electric waves that move across the brain and cause pain and inflammation).
All substitutes for Graincide Tablet SR
For information purposes only. Consult a doctor before taking any medicine.
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Quick tips
- You have been prescribed Graincide Tablet SR for prevention of migraine headaches.
- Do not take it to treat an acute attack of migraine.
- Some tips that may help avoid a migraine attack:
- Have your meals at the same time everyday
- Avoid bright lights and extreme temperatures
- Avoid loud music and noisy places
- Avoid chocolates, cheese, processed food, alcohol and smoking
- Get sufficient sleep and avoid stress
- It should be taken at night-time before going to bed.
- It may cause sleepiness. Don't drive or do anything that requires mental focus until you know how Graincide Tablet SR affects you.
- keep taking it regularly every day, even if you don't have any symptoms.
Safety advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Graincide Tablet SR.

Pregnancy
CONSULT YOUR DOCTOR
Graincide Tablet SR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Graincide Tablet SR during breastfeeding is not available. Please consult your doctor.

Driving
UNSAFE
Graincide Tablet SR may cause side effects which could affect your ability to drive.
Graincide Tablet SR may cause visual disturbances, hallucinations, fatigue, mental confusion, dizziness or tiredness. This may affect your driving ability.
Graincide Tablet SR may cause visual disturbances, hallucinations, fatigue, mental confusion, dizziness or tiredness. This may affect your driving ability.

Kidney
SAFE IF PRESCRIBED
Graincide Tablet SR is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Graincide Tablet SR may not be needed in these patients. Please consult your doctor.

Liver
CAUTION
Graincide Tablet SR should be used with caution in patients with liver disease. Dose adjustment of Graincide Tablet SR may be needed. Please consult your doctor.
Regular monitoring of blood pressure is advisable for dose adjustment.
Regular monitoring of blood pressure is advisable for dose adjustment.

Frequently asked questions
Use of Graincide Tablet SR is considered to be harmful for patients with allergy to any of the ingredients or excipients of this medicine. This medicine contains propranolol, so its use should be avoided in patients with asthma, slow heart rate, abnormal heart rhythms, or heart conditions like AV block or sick sinus syndrome. Since this medicine also contains flunarizine, the use of this medicine should be avoided in patients with the history of depression or Parkinson's disease.
Keep Graincide Tablet SR in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
Graincide Tablet SR is given as a prophylactic treatment for the prevention of migraine headaches. Do not stop taking this medicine until advised by your doctor as it may cause your migraine episodes to return. This medicine contains propranolol and a sudden withdrawal of propranolol may cause sweating, shaking, irregular or fast heartbeat, worsening of underlying angina or heart attack. You must take Graincide Tablet SR exactly as advised by your doctor.
No, Graincide Tablet SR does not help in relieving a migraine headache that has already started. It can only be used for preventing any new episode of migraine headaches.
Fact Box
Habit Forming
No
Therapeutic Class
CARDIAC
References
- Drugs.com. Flunarizine. [Accessed 25 Mar. 2019] (online) Available from:
- Drugs.com. Propranolol Pregnancy and Breastfeeding Warnings. [Accessed 20 Mar. 2019] (online) Available from:
- Flunarizine. High Wycombe, Buckinghamshire: Janssen Cilag Ltd.; 2009 [revised Feb. 2014]. [Accessed 11 Apr. 2019] (online) Available from:

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Patient concerns
I am facing issue of headache from last 3-4 years.i have consulted allopathy and they have given me sibelum 10 for migrane and asked to take metopar(paracetamol) when ever pain is too much.i am nit taking sibelum now but i am taking metopar when ever required.so i want a homeopathy consultatation if it can be cured by homeopathy or the level of headache can be lowered. Currently i face headache once in a week and i had to take metopar. Kindly suggest. My weight 80 kg And i am taking some neuro medicines ( stalopam 10, amitone 10) I also have cholesterol and taking (atorec 20)
Dr. Faran Siddiqui
Homeopathy
Migraine and headache are two different things migraine is primarily headache of one side in symmetrically
I am suffering migraine. That time i'm suffer heavy headache, vomiting, over sweating What can i do? Please suggest a solution for that
Dr. Richa Jain
Ophthalmology
Consult physician for migraine
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
Marketer details
Name: Synovia Life Sciences Pvt Ltd
Address: F-1D-2D, BALAJI TOWER FIRST, FIRST FLOOR, VIDHYADHAR NAGAR JAIPUR Jaipur RJ 302023 IN
Address: F-1D-2D, BALAJI TOWER FIRST, FIRST FLOOR, VIDHYADHAR NAGAR JAIPUR Jaipur RJ 302023 IN
Vendor Details
Country of origin: India
A licensed vendor partner from your nearest location will deliver Graincide Tablet SR. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
A licensed vendor partner from your nearest location will deliver Graincide Tablet SR. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
In case of any issues, contact us
Email ID: [email protected]Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
Lab tests offered by us
- CBC (Complete Blood Count)
- FBS (Fasting Blood Sugar)
- Thyroid Profile Total (T3, T4 & TSH)
- HbA1c (Glycosylated Hemoglobin)
- Glucose - Postprandial
- Lipid Profile
- Vitamin D (25-Hydroxy)
- Urine R/M (Urine Routine & Microscopy)
- Coronavirus Covid-19 Test (RT-PCR technique)
- LFT (Liver Function Test)
- Kidney Function Test
- TSH (Thyroid Stimulating Hormone) Ultrasensitive
- ESR (Erythrocyte Sedimentation Rate)
- Uric Acid
- Vitamin B12
- C- Reactive Protein Quantitative
- Urine Culture and Sensitivity
- Serum Electrolyte
- Serum Calcium
- Creatinine
- Diabetes Screening
- KFT with Electrolytes (Kidney Function Test with Electrolytes)
- Cholesterol - Total
- Hemoglobin
- Complete Haemogram
Why we need a prescription?
Provide right medicines
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