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Guficap Injection

Caspofungin (70mg)
Genuine
Authenticity Assured
Prescription
required
Cold stored
Stored between 2-8°C
Guficap Injection is an antifungal medication. It is used in the treatment of severe fungal infections. It kills the fungi that cause these infections and thus provides relief.

Written By Dr. Betina Chandolia, MDS, BDS,
Reviewed By Dr. Lalit Kanodia, MBA, MD Pharmacology,
Last updated on 12 Nov 2024 | 01:05 AM (IST)
₹3937 MRP ₹40593% off 
 
 
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General Information

Contains

Caspofungin (70mg)

Marketer

Gufic Bioscience Ltd

Storage

Store in a refrigerator (2 - 8°C). Do not freeze.
The content is shown in English
Guficap Injection image
Guficap Injection image
Guficap Injection image
Guficap Injection image

Product introduction

Guficap Injection is administered as an injection by a healthcare professional. Kindly do not self-administer. Do not skip any doses and finish the full course of treatment even if you feel better. Your doctor may monitor your liver function regularly during treatment.

Guficap Injection may lead to a few common side effects like rash, decreased potassium level in the blood, fever, increased liver enzymes, chills, and diarrhea. You may also notice some injection site reactions like pain, swelling, or redness. Inform your doctor if these side effects persist for a longer duration. Please consult your doctor if you are pregnant, planning to conceive, or breastfeeding.

Uses of Guficap Injection

  • Severe fungal infections

Side effects of Guficap Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Guficap
  • Chills
  • Decreased potassium level in blood
  • Diarrhea
  • Fever
  • Increased alkaline phosphatase level in blood
  • Increased liver enzymes
  • Rash

How to use Guficap Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Guficap Injection works

Guficap Injection kills fungus by preventing them from making their protective covering.

Quick tips

  • Guficap Injection is given as a slow drip into vein (IV infusion) under the supervision of a doctor.
  • Do not skip any doses and finish the full course of treatment even if you feel better.
  • Your doctor may check your liver function regularly. Inform your doctor if you develop abdominal pain, loss of appetite, darkened urine or yellowing of the eyes or skin (jaundice).
  • Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
  • Guficap Injection is given as a slow drip into vein (IV infusion) under the supervision of a doctor.
  • Do not skip any doses and finish the full course of treatment even if you feel better.
  • Your doctor may check your liver function regularly. Inform your doctor if you develop abdominal pain, loss of appetite, darkened urine or yellowing of the eyes or skin (jaundice).
  • Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Guficap Injection. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Guficap Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding

Breast feeding

SAFE IF PRESCRIBED
Guficap Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving

Driving

CONSULT YOUR DOCTOR
It is not known whether Guficap Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney

Kidney

SAFE IF PRESCRIBED
Guficap Injection is safe to use in patients with kidney disease. No dose adjustment of Guficap Injection is recommended.
Liver

Liver

CAUTION
Guficap Injection should be used with caution in patients with liver disease. Dose adjustment of Guficap Injection may be needed. Please consult your doctor.
Limited information is available on the use of Guficap Injection in patients with the severe liver disease.

Frequently asked questions

Guficap Injection is used to treat serious fungal as well as yeast infections in the blood, stomach, lungs, and food pipe (esophagus).
Yes, Guficap Injection is an antifungal antibiotic. It kills the fungi and yeast causing serious infections and helps in clearing the infection.
Guficap Injection should be administered as an injection into a vein under the supervision of a trained healthcare professional or a doctor only usually once a day. It should be injected slowly over 1 hour and should not be self-administered. The dose will depend on the condition you are being treated for and will be decided by your doctor. Follow your doctor’s instructions carefully to get maximum benefit from Guficap Injection.
Guficap Injection targets an essential component of the outermost layer (cell wall) of the fungus, called beta-(1,3)-D-glucan. This component is present in the Aspergillus species and Candida species but not present in mammalian cells. Guficap Injection stops the synthesis of this component and this kills the fungus, inhibits further growth, thereby clearing the infection.
Guficap Injection is effective if used in the dose and duration advised by your doctor. Do not stop taking it even if you see improvement in your condition. If you stop using Guficap Injection too early, the symptoms may return or worsen.

Fact Box

Chemical Class

Echinocandins

Habit Forming

No

Therapeutic Class

ANTI INFECTIVES

Action Class

Fungal cell wall synthesis inhibitor (Echiocandins)

References

  1. Bennett JE. Antifungal Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. pp. 1583-84.
  2. Sheppard D, Lampiris HW. Antifungal Agents. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 841.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 216-17.
  4. Caspofungin acetate. Hoddesdon, Hertfordshire: Merck Sharp & Dohme Limited; 2001 [revised 08 Aug. 2018]. [Accessed 29 Mar. 2019] (online) Available from:
  5. Caspofungin. White House Station, New Jersey: Merck & Co.; 2001. [Accessed 29 Mar. 2019] (online) Available from:
  6. Central Drugs Standard Control Organisation (CDSCO). [Accessed 29 Mar. 2019] (online) Available from:
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User feedback

Serious fungal infections
75%
Others
25%
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Gufic Bioscience Ltd
Address: 37,1st Floor, Kamala Bhavan II, Swami Nityanand Road, Andheri (East), Mumbai - 400 069. (INDIA)

Vendor Details

Country of origin: India
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