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Hydrogem 500mg Capsule

Written By Dr. Anuj Saini, MMST, MBBS
Reviewed By Dr. Lalit Kanodia, MBA, MD Pharmacology
Last updated on 12 Nov 2024 | 01:01 AM (IST)
Hydrogem 500mg Capsule is used in the treatment of some kinds of cancer and to prevent painful episodes associated with sickle cell anemia. It may be also used to treat some other conditions. It is sometimes used with certain other medicines as part of combination chemotherapy.
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General Information

The content is shown in English
Hydrogem 500mg Capsule image
Hydrogem 500mg Capsule image
Hydrogem 500mg Capsule image
Hydrogem 500mg Capsule image
Hydrogem 500mg Capsule image
Hydrogem 500mg Capsule image

Product introduction

Hydrogem 500mg Capsule can be taken with or without food, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

The most common side effects of this medicine include hematological disorders, gastrointestinal symptoms, eating disorders, and weight loss. This medicine may reduce the number of blood cells in your blood thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with kidney, liver and heart function during treatment with this medicine.

Before taking it, tell your doctor if you have bleeding, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Uses of Hydrogem Capsule

Side effects of Hydrogem Capsule

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Hydrogem
  • Skin cancer
  • Azoospermia (absence of sperms)
  • Decreased appetite
  • Fever
  • Oligospermia (low sperm count)
  • Bone marrow suppression
  • Hallucination
  • Convulsion
  • Peripheral neuropathy (tingling and numbness of feet and hand)
  • Pulmonary fibrosis
  • Pulmonary edema
  • Pancreatic inflammation
  • Liver toxicity
  • Cutaneous vasculitis
  • Increased uric acid level in blood
  • Hematological disorder
  • Gastrointestinal disorder
  • Eating disorder

How to use Hydrogem Capsule

Take this medicine in the dose and duration as advised by your doctor. Hydrogem 500mg Capsule may be taken with or without food, but it is better to take it at a fixed time.

How Hydrogem Capsule works

In cancer, Hydrogem 500mg Capsule works by blocking an enzyme (ribonucleotide reductase) which is required for synthesis of DNA. This prevents the cancer cells from growing and multiplying. In sickle cell disease, it works by increasing fetal haemoglobin (HbF) levels in red blood cells (RBCs). This helps the RBCs assume a normal shape, improves blood flow and protects against complications such as painful sickle cell episodes.

Quick tips

  • Take it at the same time every day, either with or without food.
  • It is advisable to stay hydrated and drink plenty of fluids while taking Hydrogem 500mg Capsule.
  • Do not skip any dose and complete the course as suggested by your doctor.
  • Use an effective method of birth control to avoid pregnancy while taking this medication.
  • Your doctor may get regular blood tests done to monitor your electrolyte levels, liver function, blood cell count in your blood.
  • Take it at the same time every day, either with or without food.
  • It is advisable to stay hydrated and drink plenty of fluids while taking Hydrogem 500mg Capsule.
  • Do not skip any dose and complete the course as suggested by your doctor.
  • Use an effective method of birth control to avoid pregnancy while taking this medication.
  • Your doctor may get regular blood tests done to monitor your electrolyte levels, liver function, blood cell count in your blood.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Hydrogem 500mg Capsule. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Hydrogem 500mg Capsule is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Hydrogem 500mg Capsule is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving

Driving

UNSAFE
Hydrogem 500mg Capsule may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney

Kidney

CAUTION
Hydrogem 500mg Capsule should be used with caution in patients with kidney disease. Dose adjustment of Hydrogem 500mg Capsule may be needed. Please consult your doctor.
Regular monitoring of kidney function test and some blood tests may be advised while you are taking this medicine.
Liver

Liver

CAUTION
Hydrogem 500mg Capsule should be used with caution in patients with liver disease. Dose adjustment of Hydrogem 500mg Capsule may be needed. Please consult your doctor.
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Frequently asked questions

Food items with soluble fiber can help relieve diarrhea as they help absorb excess fluid from the body. These food items include bananas (ripe), oranges, boiled potatoes, white rice, curd, and oatmeal. Diarrhea can cause dehydration in the body, so drink 8-10 glasses of water to avoid dehydration. You can also have soups and juice frequently to hydrate yourself.
You can continue with your normal diet unless your doctor tells you otherwise. However, it is advisable to sip water regularly to prevent you from becoming dehydrated, eat small, simple but nourishing snacks every few hours rather than large meals, and suck on hard candy or popsicles to prevent nausea and vomiting.
Various things can help you to reduce tiredness and cope with it, for example, gentle exercise. Always consult your doctor before doing any kind of exercise.
This treatment may harm a baby developing in the womb. It is important not to become pregnant or father a child while you are having treatment and for at least 6 months afterward. Talk to your doctor about effective contraception before starting the treatment.
Yes, while taking this medicine, your hair may become brittle and break. You may also experience patchy hair loss or thinning. These conditions tend to resolve once treatment is stopped. Be gentle when brushing and washing hair to manage hair loss.
Use a moisturizer to get relief from rashes, and dry and itchy skin. Avoid direct sunlight, wear protective clothing, and use sunscreen (SPF of more than 15) whenever you step outdoors. Do not go swimming if you have a rash because the chlorine in the water can make it worse. Avoid hot water baths and wear loose and cotton fabric clothes. Your skin will tend to become better once treatment is stopped.
To relieve constipation, include fiber in your diet (fruits and vegetables), drink 8-10 glasses of fluids a day, and keep active. A stool softener (with a doctor's prescription) once or twice a day may prevent constipation. If you do not have a bowel movement for 2-3 days, consult your doctor.
Since Hydrogem 500mg Capsule lowers the number of white blood cells and platelets in your blood, it puts you at a risk of getting an infection. In order to prevent, avoid people who have infections. Check with your doctor immediately if you think you may be getting an infection, or if you get a fever, or chills.

Fact Box

Chemical Class

Anti Metabolites, {Urea}

Habit Forming

No

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Anticancer-others

References

  1. Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1721-22.
  2. Masters SB. Agents Used in Anemias; Hematopoetic Growth Factors. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 578.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 672-75.
  4. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Hydroxyurea. [Updated 2020 Jan 20]. [Accessed 18 Feb. 2020] (online) Available from:
  5. Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:
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User feedback

Once A Day
44%
Thrice A Day
30%
Twice A Day
26%
Others
67%
Sickle cell anemia
33%
Excellent
67%
Average
33%
No Side Effect
100%
Empty stomach
100%
Expensive
67%
Average
33%

Patient concerns

I'm sickle cell patient now strong pain occurs what i can do ,my MRI report uploaded

Dr. Kamal Rijhwani
Dr. Kamal Rijhwani
Physician
There is sickle cell society in NagpurFind on net and consult

the injection said is Haemaz fort Injection of 5 ml, total 4 nos. injection is injected to sickle cell disease patient, if Hb is 7 gram, what will be the effect to patient?

Dr. Pushkar Mani
Dr. Pushkar Mani
Physician
we dont treat sickle cell anaemia online, u need to consult hematologist
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Neon Laboratories Ltd
Address: 140, Damji Samji Industrial Complex, Mahakali Caves Rd., Andheri(East), Mumbai-93.

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Hydrogem 500mg Capsule. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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