INSTREL GEL
Written By Dr. Swati Mishra, BDS
Reviewed By Dr. Ashish Ranjan, MD (Pharmacology), MBBS
Last updated on 12 Nov 2024 | 01:00 AM (IST)
INSTREL GEL is a pain relieving medicine. It is used in the treatment of pain and inflammation. It helps relieve pain and swelling in postoperative wounds and other inflammatory diseases.
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General Information
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Product introduction
INSTREL GEL is for external use only. It may be prescribed alone or in combination with other medicines. You should use it as advised by your doctor. You should not use it on skin which is broken, bruised, or blistered. If it gets into your eyes, nose, or mouth, vagina, immediately rinse with plenty of water.
The medicine is well-tolerated with little or no side effects. However, if you experience any side effects which you feel is caused by the medicine, let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the symptoms.
Although medicines used on the skin are not normally affected by other medicines you should let your doctor know if you are taking any other medicine to be safe. Ask your doctor for advice if you are pregnant or breastfeeding.
The medicine is well-tolerated with little or no side effects. However, if you experience any side effects which you feel is caused by the medicine, let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the symptoms.
Although medicines used on the skin are not normally affected by other medicines you should let your doctor know if you are taking any other medicine to be safe. Ask your doctor for advice if you are pregnant or breastfeeding.
Uses of Instrel Gel
Benefits of Instrel Gel
Pain relief
INSTREL GEL gives relief in inflammatory conditions that affect muscles and joints such as rheumatoid arthritis and osteoarthritis. It also helps reduce pain and swelling after surgery. It blocks chemical messengers in the brain that are responsible for pain sensation. Along with painkillers, this medicine also contains an active ingredient called Serratiopeptidase, which is an enzyme that promotes the overall healing process and speeds up recovery. Apply INSTREL GEL 2-3 times in a day or as prescribed by the doctor. Once you see some improvement, you can start doing therapy exercises (such as walking or breathing exercises) that will help you get your strength back more quickly.
INSTREL GEL gives relief in inflammatory conditions that affect muscles and joints such as rheumatoid arthritis and osteoarthritis. It also helps reduce pain and swelling after surgery. It blocks chemical messengers in the brain that are responsible for pain sensation. Along with painkillers, this medicine also contains an active ingredient called Serratiopeptidase, which is an enzyme that promotes the overall healing process and speeds up recovery. Apply INSTREL GEL 2-3 times in a day or as prescribed by the doctor. Once you see some improvement, you can start doing therapy exercises (such as walking or breathing exercises) that will help you get your strength back more quickly.
Side effects of Instrel Gel
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Instrel
- No common side effects seen
How to use Instrel Gel
This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the gel. Wash your hands after applying, unless hands are the affected area.
How Instrel Gel works
INSTREL GEL is a combination of three medicines: Tramadol, Paracetamol and Serratiopeptidase. Tramadol is an opoid analgesic (pain reliever) which works by blocking transmission of pain signals to the brain to lower pain perception. Paracetamol is an analgesic and anti-pyretic (fever reducer) which works by blocking the release of certain chemical messengers that cause pain and fever. Serratiopeptidase is an enzyme which works by breaking down abnormal proteins at the site of inflammation, and promotes healing.
Quick tips
- INSTREL GEL is prescribed to get relief from pain.
- Apply 2-3 times daily or as prescribed by the doctor.
- Do not apply this medicine to large areas of skin or near sensitive areas such as private parts or on broken or injured skin.
- Avoid using INSTREL GEL right after bathing or shaving. Using this medication on freshly shaved skin areas can cause severe skin irritation.
- Consult your doctor if you get excessive skin irritation or other unwanted effects.
Safety advice

Alcohol
No interaction found/established

Pregnancy
CONSULT YOUR DOCTOR
INSTREL GEL may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of INSTREL GEL during breastfeeding is not available. Please consult your doctor.

Driving
No interaction found/established

Kidney
No interaction found/established

Liver
No interaction found/established

Fact Box
Habit Forming
No
Therapeutic Class
PAIN ANALGESICS
References
- Schumacher MA, Basbaum AI, Way WL. Opioid Analgesics & Antagonists. In: Katzung BG, Masters SB, Trevor AJ (Editors). Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 531-552.
- Grosser T, Smyth EM, FitzGerald GA. Pharmacotherapy of Inflammation, Fever, Pain, and Gout. In: Brunton LL, Hilal-Dandan R, Knollmann BC (Editors). Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 13th ed. New York, NY: McGraw-Hill Education; 2018. pp. 685-709.
- Yaksh T, Wallace M. Opioids, Analgesia, and Pain Management. In: Brunton LL, Hilal-Dandan R, Knollmann BC (Editors). Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 13th ed. New York, NY: McGraw-Hill Education; 2018. pp. 355-387.

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Patient concerns
One of my teeth is sensitive. It some times pains
Dr. Abhijit Gambhir
Dental Surgery
sensitivity has many causative factors for relief of pain you can take pain killers it will give temporary relief
fever and 2 months pregnant can take combiflan
Dr. Sonu Balhara Ahlawat
Obstetrics and Gynaecology
No take Crocin for pain relief
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Marketer details
Name: Dr Reddy's Laboratories Ltd
Address: Dr. Reddy's Laboratories Ltd., Village Malpur, P.O.Bhud, Baddi, Dist. Solan, H.P.
Address: Dr. Reddy's Laboratories Ltd., Village Malpur, P.O.Bhud, Baddi, Dist. Solan, H.P.
Vendor Details
Country of origin: India
Lab tests offered by us
- CBC (Complete Blood Count)
- FBS (Fasting Blood Sugar)
- Thyroid Profile Total (T3, T4 & TSH)
- HbA1c (Glycosylated Hemoglobin)
- Glucose - Postprandial
- Lipid Profile
- Vitamin D (25-Hydroxy)
- Urine R/M (Urine Routine & Microscopy)
- Coronavirus Covid-19 Test (RT-PCR technique)
- LFT (Liver Function Test)
- Kidney Function Test
- TSH (Thyroid Stimulating Hormone) Ultrasensitive
- ESR (Erythrocyte Sedimentation Rate)
- Uric Acid
- Vitamin B12
- C- Reactive Protein Quantitative
- Urine Culture and Sensitivity
- Serum Electrolyte
- Serum Calcium
- Creatinine
- Diabetes Screening
- KFT with Electrolytes (Kidney Function Test with Electrolytes)
- Cholesterol - Total
- Hemoglobin
- Complete Haemogram
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