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Japiref Plus 100mg/325mg Tablet

Written By Dr. Anuj Saini, MMST, MBBS
Reviewed By Dr. Ashish Ranjan, MD (Pharmacology), MBBS
Last updated on 05 Sep 2024 | 01:15 AM (IST)
Japiref Plus 100mg/325mg Tablet is a pain relieving medicine. It is used to treat pain and inflammation in conditions like rheumatoid arthritis, ankylosing spondylitis, and osteoarthritis. It is also used to relieve muscle pain, back pain, toothache, or pain in the ear and throat.
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General Information

Contains

Flupirtine (100mg)+ Paracetamol (325mg)

Marketer

Kiama Lifesciences

Storage

Store below 30°C
The content is shown in English
Japiref Plus 100mg/325mg Tablet image

Product introduction

Japiref Plus 100mg/325mg Tablet should be taken with food. This will prevent you from getting an upset stomach. The dose will depend on what you are taking it for and how well it helps your symptoms. You should take it as advised by your doctor. Do not take more or use it for a longer duration than recommended by the doctor.

The most common side effects of this medicine include nausea, vomiting, constipation, dryness in mouth, dizziness, headache, and sleepiness. If any of these side effects bother you or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the side effects.

Before taking it, you should let your doctor know if you have a history of ulcer or bleeding in your stomach, high blood pressure, or have any trouble with your heart, kidneys, or liver. Let your doctor also know about all the other medicines you are taking because they may affect, or be affected by, this medicine. Pregnant or breastfeeding women should consult their doctor before starting treatment. You should also avoid drinking alcohol while you are taking this medicine, as alcohol can cause excessive drowsiness.

Uses of Japiref Plus Tablet

Benefits of Japiref Plus Tablet

Pain relief
Japiref Plus 100mg/325mg Tablet is used to treat pain associated with muscles, joints, cancer, dysmenorrhoea (severe abdominal pain during menstruation), tension headache and pain following orthopaedic surgery or injuries. It works by reducing substances in the body that cause pain. Take Japiref Plus 100mg/325mg Tablet as prescribed by the doctor.

Side effects of Japiref Plus Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Japiref Plus
  • Nausea
  • Vomiting
  • Constipation
  • Dryness in mouth
  • Dizziness
  • Headache
  • Sleepiness

How to use Japiref Plus Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Japiref Plus 100mg/325mg Tablet is to be taken with food.

How Japiref Plus Tablet works

Japiref Plus 100mg/325mg Tablet is a combination of two medicines: Flupirtine and Paracetamol, which relieves pain. Flupirtine is an analgesic (pain reliever) which works by blocking transmission of pain signals to the brain to lower pain perception. Paracetamol is an analgesic (pain reliever) and an anti-pyretic (fever reducer) which works by blocking the release of certain chemical messengers that cause fever and pain.

All substitutes for Japiref Plus 100mg/325mg Tablet

For information purposes only. Consult a doctor before taking any medicine.

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Quick tips

  • You have been prescribed this combination medicine for relieving pain and inflammation.
  • Take it with food to avoid getting an upset stomach.
  • Do not take indigestion remedies (antacids) within two hours of taking Japiref Plus 100mg/325mg Tablet.
  • Do not take it with any other pain medicine without asking your doctor first.

Safety advice

Alcohol

Alcohol

UNSAFE
It is unsafe to consume alcohol with Japiref Plus 100mg/325mg Tablet.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Japiref Plus 100mg/325mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Information regarding the use of Japiref Plus 100mg/325mg Tablet during breastfeeding is not available. Please consult your doctor.
Driving

Driving

CONSULT YOUR DOCTOR
It is not known whether Japiref Plus 100mg/325mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney

Kidney

CAUTION
Japiref Plus 100mg/325mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Japiref Plus 100mg/325mg Tablet may be needed. Please consult your doctor.
Liver

Liver

CAUTION
Japiref Plus 100mg/325mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Japiref Plus 100mg/325mg Tablet may be needed. Please consult your doctor.
However, the use of Japiref Plus 100mg/325mg Tablet is not recommended in patients with severe liver disease and active liver disease.

Frequently asked questions

Japiref Plus 100mg/325mg Tablet is usually used for short term and can be discontinued when your pain is relieved. However, Japiref Plus 100mg/325mg Tablet should be continued if you are advised by your doctor to do so.
Japiref Plus 100mg/325mg Tablet contains Paracetamol, which is known to cause liver damage. Also, avoid drinking alcohol while taking this medicine, as it may further increase your risk of liver damage. Use of this medicine should preferably be avoided in patients with underlying liver disease.
No, taking a higher than the recommended dose of Japiref Plus 100mg/325mg Tablet can lead to increased chances of side effects. If the recommended doses do not relieve your symptoms of if you experience increased severity of pain, please consult your doctor for re-evaluation.
Keep this medicine in the packet or the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Fact Box

Habit Forming

No

Therapeutic Class

PAIN ANALGESICS

References

  1. Harish S, Bhuvana K, Bengalorkar GM, et al. Flupirtine: Clinical pharmacology. J Anaesthesiol Clin Pharmacol. 2012;28(2):172-7. [Accessed 24 Jan. 2019] (online) Available from:
  2. ScienceDirect. Flupirtine. [Accessed 02 Apr. 2019] (online) Available from:
  3. ScienceDirect. Paracetamol. [Accessed 02 Apr. 2019] (online) Available from:
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Patient concerns

One of my teeth is sensitive. It some times pains

Dr. Abhijit Gambhir
Dr. Abhijit Gambhir
Dental Surgery
sensitivity has many causative factors for relief of pain you can take pain killers it will give temporary relief

fever and 2 months pregnant can take combiflan

Dr. Sonu Balhara Ahlawat
Dr. Sonu Balhara Ahlawat
Obstetrics and Gynaecology
No take Crocin for pain relief
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Kiama Lifesciences
Address: Scf. No. 4 Second Floor, Sector 2, Panchkula, Haryana 134112

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Japiref Plus 100mg/325mg Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's â„ž and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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Why we need a prescription?
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Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945
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