Joclab Injection
Written By Dr. Anuj Saini, MMST, MBBS
Reviewed By Dr. Varun Gupta, MD Pharmacology, MBBS
Last updated on 12 Nov 2024 | 01:03 AM (IST)
Joclab Injection is used in the treatment of hairy cell leukemia, a cancer of the blood and bone marrow. It may be also used to treat other conditions, as determined by the doctor. It is used alone or in combination with some other medicines as a part of the combination therapy.
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General Information
Contains
Cladribine (1mg/ml)
Marketer
Jodas Expoim
Storage
Store in a refrigerator (2 - 8°C). Do not freeze.
The content is shown in English




Product introduction
Joclab Injection is given as an injection into the vein under the supervision of a doctor. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
The most common side effects of this medicine include nausea, fatigue, headache, and rash. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections or bleeding. Inform your doctor if you notice chills, unusual bleeding or bruising and black and tarry stools. Regular blood tests are required to check your blood cells along with heart, liver, and blood uric acid levels.
Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
The most common side effects of this medicine include nausea, fatigue, headache, and rash. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections or bleeding. Inform your doctor if you notice chills, unusual bleeding or bruising and black and tarry stools. Regular blood tests are required to check your blood cells along with heart, liver, and blood uric acid levels.
Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
Uses of Joclab Injection
Benefits of Joclab Injection
Hairy cell leukemia
Hairy cell leukemia is a kind of blood cancer in which there is excessive production of specific white blood cells (that fight infections) and they resemble hairy-shape when seen under a microscope. Joclab Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is an effective medicine but you should discuss the side effects and benefits of this medicine with your doctor. You should avoid drinking alcohol and smoking while having this treatment and drink plenty of water to stay hydrated.
Hairy cell leukemia is a kind of blood cancer in which there is excessive production of specific white blood cells (that fight infections) and they resemble hairy-shape when seen under a microscope. Joclab Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is an effective medicine but you should discuss the side effects and benefits of this medicine with your doctor. You should avoid drinking alcohol and smoking while having this treatment and drink plenty of water to stay hydrated.
Side effects of Joclab Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Joclab
- Nausea
- Fatigue
- Headache
- Rash
- Fever
- Injection site allergic reaction
How to use Joclab Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Joclab Injection works
Joclab Injection interferes with the growth of DNA and RNA of the cancer cells by substituting their building blocks. It prevents the cancer cells from growing and multiplying.
Quick tips
- Joclab Injection helps treat hairy cell leukaemia.
- It is given by a drip into a vein.
- Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine.
- Inform your doctor immediately if you notice any signs of infection such as fever, sore throat, rash or severe diarrhea.
Safety advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Joclab Injection. Please consult your doctor.

Pregnancy
CONSULT YOUR DOCTOR
Joclab Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding
CONSULT YOUR DOCTOR
Joclab Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving
UNSAFE
Joclab Injection may cause side effects which could affect your ability to drive.

Kidney
CAUTION
Joclab Injection should be used with caution in patients with kidney disease. Dose adjustment of Joclab Injection may be needed. Please consult your doctor.

Liver
CAUTION
Joclab Injection should be used with caution in patients with liver disease. Dose adjustment of Joclab Injection may be needed. Please consult your doctor.

Frequently asked questions
No, Joclab Injection is not a vesicant (a chemical compound that causes severe skin, eye and mucosal pain and irritation).
No, Joclab Injection does not cause hair loss.
Fact Box
Chemical Class
Purine 2'-deoxyribonucleosides Derivative
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Antimetabolites
Related lab tests
References
- Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1703-704.
- Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 948-49.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 286-87.
- Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Cetuximab. [Updated 2018 Dec 3]. [Accessed 18 Feb. 2020] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:

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Patient concerns
How to grow beard faster Please suggest how to fill patchy beard too
Dr. Souvik Sardar
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use tugain gel 5% - once daily for 3months only over hairy areas
Suffering from skin whitening leukemia
Dr. Deepak Kumar Soni
Ayurveda
Hi Kindly consult to Ayurvedic doctor at your local city area , face to face consult is needed.
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
Marketer details
Name: Jodas Expoim
Address: Survey No.376/A, Rajeev Gandhi Nagar ,IE,Plot no. 40, houseNo:5-9-262/40, Ground, 1st &2nd Floor, Medchal -Malkajgiri,Telanagan 500072
Address: Survey No.376/A, Rajeev Gandhi Nagar ,IE,Plot no. 40, houseNo:5-9-262/40, Ground, 1st &2nd Floor, Medchal -Malkajgiri,Telanagan 500072
Vendor Details
Country of origin: India
Lab tests offered by us
- CBC (Complete Blood Count)
- FBS (Fasting Blood Sugar)
- Thyroid Profile Total (T3, T4 & TSH)
- HbA1c (Glycosylated Hemoglobin)
- Glucose - Postprandial
- Lipid Profile
- Vitamin D (25-Hydroxy)
- Urine R/M (Urine Routine & Microscopy)
- Coronavirus Covid-19 Test (RT-PCR technique)
- LFT (Liver Function Test)
- Kidney Function Test
- TSH (Thyroid Stimulating Hormone) Ultrasensitive
- ESR (Erythrocyte Sedimentation Rate)
- Uric Acid
- Vitamin B12
- C- Reactive Protein Quantitative
- Urine Culture and Sensitivity
- Serum Electrolyte
- Serum Calcium
- Creatinine
- Diabetes Screening
- KFT with Electrolytes (Kidney Function Test with Electrolytes)
- Cholesterol - Total
- Hemoglobin
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