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Justyl Injection

Written By Dr. Radhika Dua, MDS, BDS
Reviewed By Dr. Shilpa Garcha, MD (Pharmacology), MBBS
Last updated on 15 Oct 2024 | 11:47 AM (IST)
Justyl Injection is an antidote medication. It is used in the treatment of paracetamol overdose (when you may have taken too much paracetamol medicine). It protects your liver and helps to reduce the extent of the injury.
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5 ml Injection
 
 
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General Information

The content is shown in English
Justyl Injection image
Justyl Injection image
Justyl Injection image

Product introduction

Justyl Injection is given as an injection under the supervision of a doctor. It must be injected within 8 hours of paracetamol overdose. It can be given up to 24 hours, but medicine effective slow down when given after 24 hours of dosage overdose. Your doctor will decide how much you need to improve your symptoms. Always follow your doctor's advice while taking this medicine.

The most common side effects of this medicine include rash, urticaria, flushing, and itching. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them.

Before taking this medicine let your doctor know if you suffer from asthma, as close monitoring is required while taking this medicine. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding.

Uses of Justyl Injection

  • Treatment of Paracetamol toxicity

Benefits of Justyl Injection

Treatment of Paracetamol toxicity
Justyl Injection is an antidote medicine that prevents serious side effects if a person has taken more than the normal or recommended amount of a medicine called paracetamol which leads to an overdose. Initially, there may be mild gastrointestinal symptoms like nausea, vomiting, stomach pain, irritability, etc. But, if left untreated, paracetamol overdose may cause serious liver damage, which may even lead to liver failure. Rarely, an excessive overdose may lead to a coma. It is given as an injection by a doctor or nurse and should not be self-administered. Follow your doctor’s instructions carefully to get the most benefit from this medication.

Side effects of Justyl Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Justyl
  • Rash
  • Red spots or bumps
  • Flushing (sense of warmth in the face, ears, neck and trunk)
  • Itching

How to use Justyl Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Justyl Injection works

Justyl Injection is an antidote for paracetamol poisoning. It works by increasing the level of glutathione, an antioxidant that neutralises the toxic products of paracetamol.

Quick tips

  • Justyl Injection is used for the treatment of paracetamol overdose (when you may have taken too much paracetamol).
  • It protects the liver from damage by the high levels of paracetamol.
  • It is very effective when given during the first 8 hours following paracetamol overdose. The effectiveness is reduced with time but it can still help when given within 24 hours. 

Safety advice

Alcohol

Alcohol

SAFE
Consuming alcohol with Justyl Injection does not cause any harmful side effects.
Pregnancy

Pregnancy

SAFE IF PRESCRIBED
Justyl Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Breast feeding

Breast feeding

SAFE IF PRESCRIBED
Justyl Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving

Driving

SAFE
Justyl Injection does not usually affect your ability to drive.
Kidney

Kidney

SAFE IF PRESCRIBED
Justyl Injection is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Justyl Injection may not be needed in these patients. Please consult your doctor.
Liver

Liver

SAFE IF PRESCRIBED
Justyl Injection is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Justyl Injection may not be needed in these patients. Please consult your doctor.

Frequently asked questions

Yes, Justyl Injection is good for the liver. It improves liver function and activity in patients with non-alcoholic fatty liver disease. It also prevents liver from toxic agents which can damage the liver. Additionally, it also prevents liver from damage in cases of drug overdose like paracetamol, etc.
Yes, Justyl Injection by acting through various mechanism prevents the rise of blood pressure and maintains the normal functioning of the body. There are reports which show that Justyl Injection can prevent damage to the inner lining of the blood vessels of the body, which will maintain the elasticity and vitality of the blood vessels. It also increases the antioxidants levels in the body hence preventing the body from oxidative damage.
There is no concrete evidence that Justyl Injection can be used alone in the treatment of anxiety disorder. However, in some reports, it is shown that Justyl Injection provides benefit by acting as an antioxidant. This property prove to be beneficial in psychiatric and neurological conditions when added to the normal treatment of the particular disorder. Do not take this medication without consulting your doctor. Contact the doctor for any query if you feel anxious.
Yes, Justyl Injection is beneficial when used in patients with impaired kidney functions. It is also used to prevent or minimize the damage caused by the use of contrast during investigations like CT scan or other body scans.
Unopened vials of Justyl Injection should be stored at room temperature. Once the medicine is opened and diluted it should be used within 3 hours as per the directions of the physician. It should not be stored above 25ÂșC. Once opened, the vials should be stored in refrigeration and if unused then should be discarded after 96 hours.

Fact Box

Chemical Class

N-Acylated Alpha Amino Acids

Habit Forming

No

Therapeutic Class

OTHERS

Action Class

Acetylcysteine -Mucolytic

References

  1. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 13-15.
  2. Acetylcysteine (N-Acetylcysteine). In: Hitchings A, Lonsdale D, Burrage D, et al., editors. The Top 100 Drugs: Clinical Pharmacology and Practical Pescribng. Churchil Livingstone Elsevier; 2015.
  3. Acetylcysteine. Romford, Essex: Martindale Pharma; 2004 [revised 23 Feb. 2017]. [Accessed 01 Apr. 2019] (online) Available from:
  4. Acetylcysteine. Nashville, Tennessee: Cumberland Pharmaceuticals Inc.; 2004 [revised Jun. 2013]. [Accessed 31 Jan. 2019] (online) Available from:
  5. Acetylcysteine Injection [Prescribing Information]. Lake Zurich, IL: Fresenius Kabi; 2018. [Accessed 09 Jun, 2023] (online) Available from:
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Patient concerns

Is there any toxic effect for the drug garoin(phenobarbitone and phenytoin) in constipation child If the child doesnot having epilepsy also??

Dr. Gopal Samdani
Dr. Gopal Samdani
Paediatrics
Toxicity is dose dependent

Ferrous sulphate tablets toxicity

Dr. Megha Gupta
Dr. Megha Gupta
Obstetrics and Gynaecology
There is no toxicity as such. Please be specific in what respect are you asking.
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Human Biolife India Pvt Ltd
Address: Plot No 303, Industrial Area Phase -2, Panchkula (Haryana)-134109

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Justyl Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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