


Kadcyla 100mg Injection
Written By Dr. Anuj Saini, MMST, MBBS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 12 Nov 2024 | 01:10 AM (IST)
General Information



Product introduction
Kadcyla 100mg Injection is administered through an intravenous (IV) infusion under the supervision of a doctor or a nurse, typically in a clinic or hospital setting. It is given once every three weeks, and each infusion session may take around 30–90 minutes, depending on individual treatment needs. Attend all scheduled infusion sessions to maintain consistent drug levels for maximum benefits.
Common side effects of Kadcyla 100mg Injection include fatigue, nausea, vomiting, headache, constipation, mild liver enzyme changes, and muscle or joint pain. If you experience nausea, try eating small, frequent meals and avoid heavy or greasy foods. Fatigue can be managed by resting when needed and pacing activities. Let your doctor know if any of these side effects persist or worsen. They may be able to help ways to reduce or prevent the side effects.
Before receiving this medicine, inform your doctor if you have a history of liver or heart issues, as this medication can affect these organs. This treatment is not recommended for pregnant women, as it may harm the unborn baby; women of childbearing age should use effective contraception during treatment and for several months after. Additionally, avoid breastfeeding during and after treatment, as the drug may pass into breast milk.
There is a Patient Support Program/Patient Assistance Program available in India for this medicine, being managed by Tata 1mg. Please contact your prescribing doctor to know more about the same. You may also call on (1800-102-1618) for more details.
Uses of Kadcyla Injection
- Treatment of Metastatic breast cancer
Benefits of Kadcyla Injection
In the treatment of metastatic breast cancer, Kadcyla 100mg Injection targets cancer and minimizes damage to healthy cells. This targeted mechanism helps slow tumor growth, reduce cancer spread, and result in fewer side effects than traditional chemotherapy. Kadcyla 100mg Injection helps improve treatment outcomes and enhance the quality of life for patients with advanced breast cancer.
Side effects of Kadcyla Injection
- Nausea
- Diarrhea
- Headache
- Vomiting
- Constipation
- Dryness in mouth
- Abdominal pain
- Fatigue
- Fever
- Weakness
- Urinary tract infection
- Low blood platelets
- Anemia (low number of red blood cells)
- Insomnia (difficulty in sleeping)
- Peripheral neuropathy (tingling and numbness of feet and hand)
- Hemorrhage
- Nosebleeds
- Cough
- Breathlessness
- Stomatitis (Inflammation of the mouth)
- Increased transaminase level in blood
- Musculoskeletal (bone, muscle or joint) pain
- Joint pain
- Muscle pain
How to use Kadcyla Injection
How Kadcyla Injection works
Quick tips
- Make sure to attend all scheduled infusion sessions for maximum benefits.
- If you experience side effects like fatigue, nausea, or muscle pain, report them to your doctor. Early management can keep you comfortable throughout treatment.
- Staying hydrated and eating a balanced diet can help you manage side effects such as nausea and fatigue. Opt for light, nutritious meals and avoid greasy or heavy foods.
- This treatment is not safe during pregnancy, so women of childbearing age should use effective contraception during and for several months after treatment. Consult your doctor for guidance on safe contraceptive options.
- Fatigue is a common side effect, so prioritize rest and pace your daily activities. Gentle exercise, such as walking or stretching, may help boost energy levels without overexerting yourself.
Safety advice

Alcohol

Pregnancy

Breast feeding

Driving
Do not drive and use machines if you experience fatigue, headache, dizziness, and blurred vision on receiving the injection.

Kidney

Liver
Frequently asked questions
Fact Box
Chemical Class
Habit Forming
Therapeutic Class
Action Class
References
- Trastuzumab Emtansine [Summary of Product Characteristics]. Grenzach-Wyhlen, Germany: Roche Pharma AG; 2018. [Accessed 30 Oct. 2024] (online) Available from:
- Trastuzumab Emtansine [Package Insert]. Dee Why, NSW: Roche Products Pty Limited; 2014. [Accessed 30 Oct. 2024] (online) Available from:
- Trastuzumab emtansine [Product Monograph]. Mississauga, Ontario: Hoffmann-La Roche Limited; 2022. [Accessed 30 Oct. 2024] (online) Available from:




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