Kyfil 10mg Injection

Reviewed By Dr. Ashish Ranjan, MD (Pharmacology), MBBS

Last updated on 12 Nov 2024 | 01:07 AM (IST)

Kyfil 10mg Injection is used in the treatment of multiple myeloma. It shows its working by stopping or slowing down the growth of cancer cells.

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Cold stored

Stored between 2-8°C

₹2900

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₹2610

on orders above ₹150

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₹2668

on orders above ₹200

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1/2

1 Injection

General Information

Contains

Carfilzomib (10mg)

Marketer

MSN Laboratories

Storage

Store in a refrigerator (2 - 8°C). Do not freeze.

The content is shown in English

Product introduction

Kyfil 10mg Injection is given as an injection by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

Fatigue, nausea, and fever are some common side effects of this medicine. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. Hence, inform your doctor if you notice fever, chills, joint or muscle pain, flushing or swelling of the face, and chest pain. You are advised to drink plenty of fluids while taking this medicine.

Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Uses of Kyfil Injection

Multiple myeloma

Benefits of Kyfil Injection

Multiple myeloma
If you have multiple myeloma, your body is destroying bone faster than it is being replaced. This makes bones weak and painful and more likely to break. Kyfil 10mg Injection may be prescribed along with other cancer treatments such as chemotherapy. It is an important part of your treatment and increases the survival rate of people with multiple myeloma. This medicine will kill the cancerous cells and prevent their further growth as well as spread to other parts of the body. Follow your doctor’s instructions carefully to get the most benefit. Supplements of calcium and Vitamin D3 are also effective and may be prescribed if you do not have high blood calcium levels.

Side effects of Kyfil Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Kyfil

Fatigue
Anemia (low number of red blood cells)
Nausea
Low blood platelets
Fever

How to use Kyfil Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Kyfil Injection works

Kyfil 10mg Injection is an anti-cancer medication. It works by blocking or slowing the breakdown of proteins in cells. As a result, there is an increase in a number of proteins in the cancer cells leading to their death.

Quick tips

Kyfil 10mg Injection is given as an infusion into the vein ( IV infusion) under the supervision of a doctor only.
Do not skip any dose and complete the course as suggested by your doctor.
Use an effective method of birth control to avoid pregnancy while taking this medication.
You may need to have blood tests to monitor your blood cells, platelets count, liver function and kidney function during treatment.
Inform your doctor immediately if you notice unusual bruising or bleeding or if you have dark, tarry, or bloody stools and sore throat.
Let your doctor know if you notice chest pains, shortness of breath, difficulty breathing, dizziness and swelling of feet.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Kyfil 10mg Injection. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Kyfil 10mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding

UNSAFE

Kyfil 10mg Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving

UNSAFE

Kyfil 10mg Injection may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Kyfil 10mg Injection should be used with caution in patients with kidney disease. Dose adjustment of Kyfil 10mg Injection may be needed. Please consult your doctor.

Liver

CAUTION

Kyfil 10mg Injection should be used with caution in patients with liver disease. Dose adjustment of Kyfil 10mg Injection may be needed. Please consult your doctor.

Frequently asked questions

Is Kyfil 10mg Injection right for me?

Kyfil 10mg Injection in combination with other medications is for patients with relapsed multiple myeloma (multiple myeloma that has returned) and for refractory multiple myeloma (multiple myeloma that no longer responds to treatment). talk to your doctor in case of any doubts.

How is Kyfil 10mg Injection administered?

Kyfil 10mg Injection is given as an intravenous (IV) infusion. This is a way to put fluids, including medicine, into your bloodstream through a vein.

How often will I be given Kyfil 10mg Injection?

You may receive this injection in treatment cycles. Each cycle lasts 4 weeks. The cycle includes days when you are given treatment and days when you do not have treatment (rest periods). You will usually have Kyfil 10mg Injection 2 days a week for 3 weeks. In week 4 you do not have treatment. Your doctor will decide your treatment plan depending on what will work best for you.

I am experiencing nausea and extreme tiredness. Is this due to Kyfil 10mg Injection?

Nausea and fatigue or tiredness are some of the common side-effects of this medicine. Eat smaller, more frequent meals to reduce the feeling of nausea. Avoid food that is salty, spicy, fried, or fatty. Take plenty of rest and do light exercise daily to keep yourself active and reduce fatigue.

Does Kyfil 10mg Injection reduce immunity?

After the start of the treatment with this medicine, your platelet count might become low. As a result, you may be at risk of infection. It is therefore advisable to avoid crowds or people with colds and infections. Wash your hands often and always after using the bathroom.

When should I seek a doctor’s advice?

You should contact your doctor immediately if you develop shortness of breath, prolonged, unusual, or excessive bleeding, yellowing of the skin and/or eyes (jaundice), severe headache, confusion, seizures, or loss of sight.

Can Kyfil 10mg Injection be used during pregnancy?

Kyfil 10mg Injection can cause harm to the unborn baby when given to a pregnant woman. Women should use effective contraception during treatment with this medicine and for 6 months following the final dose. Men should use effective contraception during treatment and for 3 months following the final dose.

Can Kyfil 10mg Injection be used during breastfeeding?

This medicine may pass into breastmilk and harm the baby. Therefore it is advisable not to breastfeed during the treatment and for 2 weeks after the final dose.

What are some of the precautions to be taken while on treatment with Kyfil 10mg Injection?

You might get dehydrated while on treatment with Kyfil 10mg Injection, so it is advisable to increase your fluid intake. This medicine might make you feel dizzy so it is advisable not to drive or operate any machinery. Avoid sun exposure and wear SPF 15 (or higher) sunblock and protective clothing in order to prevent rashes.

Fact Box

Chemical Class

Epoxomicin Derivate

Habit Forming

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Proteasome inhibitor

Related lab tests

Albumin/Globulin Ratio, Serum

Calcium

Complete Blood Count

Kidney Function Test

References

Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 209.
Carfilzomib. Netherlands: Amgen Europe B.V.; 2015 [revised Sep. 2018]. [Accessed 26 Mar. 2019] (online) Available from:
Carfilzomib. South San Francisco, California: Onyx Pharmaceuticals; 2012. [Accessed 26 Mar. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:

Patient concerns

Please tell me the interpretation of the attach report, if possible. Also guide for further treatment process.

Dr. Sanjay Singh Rai

Medical Oncology and Hematology

U r having multiple myeloma

Multiple myeloma can be cured or not

Dr. Rohan Khandelwal

Surgical Oncology

Yes, if diagnosed at the right stage

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: MSN Laboratories
Address: MSN House, Plot No: C-24, Industrial Estate, Sanathnagar, Hyderabad - 18 Telangana, INDIA

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Kyfil 10mg Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

Lab tests offered by us

Why we need a prescription?

Provide right medicines

Prescriptions are complex documents. We proof read and recheck at various steps to provide you the right medication in the correct form and dose

In accordance with the law

Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945