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Lodiric-SR 250mg Capsule

Written By Dr. Betina Chandolia, MDS, BDS
Reviewed By Dr. Lalit Kanodia, MBA, MD Pharmacology
Last updated on 12 Nov 2024 | 01:08 AM (IST)
Lodiric-SR 250mg Capsule is a medicine used to treat and prevent gout. Gout happens when there is too much uric acid in your body and it forms into crystals that can appear around your joints and kidneys and cause pain. This medicine helps to keep uric acid levels low.
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General Information

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Product introduction

Lodiric-SR 250mg Capsule should be taken after food. You should keep taking it as recommended by your doctor even when you are not having a gout attack. If you stop, your symptoms may get worse because more crystals form in your joints and kidneys. You can help yourself by making some changes to your diet and drinking plenty of fluids.

Some of the common side effects of this medicine are nausea, diarrhea, increased serum glutamic oxaloacetic transaminase and serum glutamate pyruvate transaminase, and increased alkaline phosphatase. Your doctor may help with ways to reduce or prevent these symptoms. Some people may get a severe allergic reaction that needs urgent medical attention. Talk to your doctor straight away if you get symptoms of liver disease including nausea that does not stop, yellowing skin or eyes, or dark urine.

To make sure it is safe for you, before taking this medicine, let your doctor know if you have or have had heart failure, heart problems, stroke, kidney or liver disease, or thyroid problems. Do not use this medicine if you are pregnant or breastfeeding. Check with your doctor. You will be asked for regular blood tests to check that your liver is working properly.

Uses of Lodiric Capsule SR

Benefits of Lodiric Capsule SR

Treatment of Gout
Lodiric-SR 250mg Capsule is used to prevent and treat gout. Gout is caused by too much uric acid in your body. When the level becomes too high, crystals may form in and around certain joints and your kidneys. This can cause sudden and severe pain, redness, warmth, and swelling. This medicine works by preventing crystals from forming and reducing the levels of uric acid in your blood. This makes it less likely that you will suffer the symptoms and make them milder if you do have them. It is usually for long-term treatment and should be taken regularly until the dose is completed.

Side effects of Lodiric Capsule SR

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Lodiric
  • Diarrhea
  • Nausea
  • Elevated serum glutamic oxaloacetic transaminase
  • Elevated serum glutamic pyruvic transaminase
  • Increased alkaline phosphatase level in blood

How to use Lodiric Capsule SR

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Lodiric-SR 250mg Capsule is to be taken with food.

How Lodiric Capsule SR works

Lodiric-SR 250mg Capsule is a xanthine oxidase inhibitor. It works by decreasing blood uric acid, which is the chemical that causes gout.

All substitutes for Lodiric-SR 250mg Capsule

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

  • Your doctor has prescribed Lodiric-SR 250mg Capsule to reduce episodes of gout attack.
  • Take Lodiric-SR 250mg Capsule with food to avoid stomach upset.
  • Take plenty of fluids (2-3 litres) daily while on Lodiric-SR 250mg Capsule.
  • Notify your doctor if you develop a rash. This could be a sign of allergy and should go away on discontinuing Lodiric-SR 250mg Capsule.
  • When you first start taking this medicine, you might have more gout attacks. Do not stop Lodiric-SR 250mg Capsule on having an acute attack of gout as that could make an attack worse.
  • Your doctor may check your liver function before starting treatment and regularly thereafter. Inform your doctor if you notice yellowing of eyes or skin, dark urine, or stomach pain.
  • Do not consume alcohol while taking this medicine as it may cause your gout to flare up.

Safety advice

Alcohol

Alcohol

CAUTION
Caution is advised when consuming alcohol with Lodiric-SR 250mg Capsule. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Lodiric-SR 250mg Capsule may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Lodiric-SR 250mg Capsule is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving

Driving

UNSAFE
Lodiric-SR 250mg Capsule may cause side effects which could affect your ability to drive.
Occasionally drowsiness, dizziness or vertigo, ataxia and visual disturbances, may occur when taking Lodiric-SR 250mg Capsule. This may affect your driving ability.
Kidney

Kidney

CAUTION
Lodiric-SR 250mg Capsule should be used with caution in patients with kidney disease. Dose adjustment of Lodiric-SR 250mg Capsule may be needed. Please consult your doctor.
Liver

Liver

CAUTION
Lodiric-SR 250mg Capsule should be used with caution in patients with liver disease. Dose adjustment of Lodiric-SR 250mg Capsule may be needed. Please consult your doctor.

Frequently asked questions

Lodiric-SR 250mg Capsule can be taken at anytime of the day but preferably should be taken at the same time each day so that you remember to take it. It is usually prescribed once daily and should be taken after meals. If the dose exceeds 300 mg or if your stomach is upset, you can take it in divided doses as advised by your doctor.
If you have started taking Lodiric-SR 250mg Capsule, you may experience an increase in attacks of gout (severe pain, swelling, and redness). However, these attacks usually become shorter and less severe after several months of therapy. The possible reason for increased attacks could be gradual breakdown of uric acid crystals, causing fluctuations in uric acid levels in the blood. To prevent such painful events, your doctor may advise to take colchicine with Lodiric-SR 250mg Capsule, as it can suppress the gouty attacks.
It may take several months before you start feeling better or notice any significant reduction in attacks of gout (severe pain, swelling, and redness). Initially after starting Lodiric-SR 250mg Capsule you may experience gouty attacks. Continue taking Lodiric-SR 250mg Capsule even if you do not experience any considerable relief from the attacks. Do not stop taking Lodiric-SR 250mg Capsule without consulting your doctor. Your doctor will prescribe you another medicine along with Lodiric-SR 250mg Capsule to prevent the initial attacks. It may take up to years for the body to completely get rid of all uric acid crystals.
You should refrain yourself from consuming alcohol while taking Lodiric-SR 250mg Capsule as this could make your condition worse. Also, you should avoid all foods that are rich source of proteins as it will help to prevent attacks of gout. Consult your doctor for a detailed list of food items which need to be avoided. It is also recommended that you drink at least 8 glasses of water or other fluids while taking Lodiric-SR 250mg Capsule, unless your doctor has advised otherwise.
Yes, Lodiric-SR 250mg Capsule may cause drowsiness in some people. It can even make you feel giddy (dizzy) or you may have problems with coordination. It would be best to avoid driving or operating machinery if you experience these side effects. However, if it is unavoidable then extreme caution should be exercised while performing such tasks.

Fact Box

Chemical Class

Pyrazolo Pyrimidine Derivative

Habit Forming

No

Therapeutic Class

PAIN ANALGESICS

Action Class

Xanthine oxidase Inhibitors-gout

References

  1. Furst DE, Ulrich RW, Varkey-Altamirano C. Nonsteroidal Anti-Inflammatory Drugs, Disease Modifying Antirheumatic Drugs, Nonopioids Analgesics, & Drugs Used in Gout. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 638-39.
  2. Grosser T, Smyth E, FitzGerald GA. Anti-Inflammatory, Antipyretic, and Analgesic Agents; Pharmacotherapy of Gout. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 996-97.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 40-42.
  4. Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 02 Apr. 2019] (online) Available from:
  5. CiplaMed. Allopurinol [Prescribing Information]. [Accessed 20 Feb. 2024] (online) Available from:
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User feedback

Once A Day
86%
Twice A Day
14%
Gout
100%
Poor
67%
Average
33%
No Side Effect
100%
Expensive
67%
Average
33%

Patient concerns

I have a uric acid problem i have been taking lodiric sr 250 mg for 4 years is zifi 200 ok for me to cure my throat infection

Dr. Anshul Varshney
Dr. Anshul Varshney
Physician
Hello, Welcome to 1mg. I am Anshul Varshney for your help. Yes, it is safe for short use in people having hyperuricemia.

Pain and swelling in toe since a week now it turns reddish,ice and hot water therapy done with pain killer

Dr. Vipul Aggarwal
Dr. Vipul Aggarwal
Orthopaedics
please get uric acid done probably gout attack as per ur history
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Novartis India Ltd
Address: Sandoz House, Shiv Sagar Estate, Worli Mumbai -400 018, India

Vendor Details

Country of origin: India
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